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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C1orf58
Full Name:
BRO1 domain-containing protein BROX
Alias:
Bro1-domain-containing protein; Brox; Chromosome 1 open reading frame 58; FLJ32421; Loc148362
Type:
Uncharacterized protein
Mass (Da):
46476
Number AA:
411
UniProt ID:
Q5VW32
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031225
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
H
R
N
P
L
K
A
T
A
P
V
S
F
N
Y
Site 2
Y20
T
A
P
V
S
F
N
Y
Y
G
V
V
T
G
P
Site 3
S38
K
I
C
N
D
L
R
S
S
R
A
R
L
L
E
Site 4
S39
I
C
N
D
L
R
S
S
R
A
R
L
L
E
L
Site 5
S51
L
E
L
F
T
D
L
S
C
N
P
E
M
M
K
Site 6
S63
M
M
K
N
A
A
D
S
Y
F
S
L
L
Q
G
Site 7
Y64
M
K
N
A
A
D
S
Y
F
S
L
L
Q
G
F
Site 8
S74
L
L
Q
G
F
I
N
S
L
D
E
S
T
Q
E
Site 9
S78
F
I
N
S
L
D
E
S
T
Q
E
S
K
L
R
Site 10
T79
I
N
S
L
D
E
S
T
Q
E
S
K
L
R
Y
Site 11
S82
L
D
E
S
T
Q
E
S
K
L
R
Y
I
Q
N
Site 12
Y86
T
Q
E
S
K
L
R
Y
I
Q
N
F
K
W
T
Site 13
T95
Q
N
F
K
W
T
D
T
L
Q
G
Q
V
P
S
Site 14
Y125
V
A
L
W
Y
T
K
Y
A
S
R
L
A
G
K
Site 15
S146
E
A
K
E
V
H
R
S
L
K
I
A
A
G
I
Site 16
S160
I
F
K
H
L
K
E
S
H
L
P
K
L
I
T
Site 17
T167
S
H
L
P
K
L
I
T
P
A
E
K
G
R
D
Site 18
S177
E
K
G
R
D
L
E
S
R
L
I
E
A
Y
V
Site 19
Y183
E
S
R
L
I
E
A
Y
V
I
Q
C
Q
A
E
Site 20
T226
F
Y
Q
K
A
D
H
T
L
S
S
L
E
P
A
Site 21
S228
Q
K
A
D
H
T
L
S
S
L
E
P
A
Y
S
Site 22
S229
K
A
D
H
T
L
S
S
L
E
P
A
Y
S
A
Site 23
Y234
L
S
S
L
E
P
A
Y
S
A
K
W
R
K
Y
Site 24
S235
S
S
L
E
P
A
Y
S
A
K
W
R
K
Y
L
Site 25
S264
H
G
E
T
L
L
A
S
D
K
C
G
E
A
I
Site 26
S273
K
C
G
E
A
I
R
S
L
Q
E
A
E
K
L
Site 27
Y281
L
Q
E
A
E
K
L
Y
A
K
A
E
A
L
C
Site 28
T294
L
C
K
E
Y
G
E
T
K
G
P
G
P
T
V
Site 29
T300
E
T
K
G
P
G
P
T
V
K
P
S
G
H
L
Site 30
Y331
Q
R
E
N
G
F
I
Y
F
Q
K
I
P
T
E
Site 31
Y348
Q
L
E
L
K
A
N
Y
G
L
V
E
P
I
P
Site 32
T361
I
P
F
E
F
P
P
T
S
V
Q
W
T
P
E
Site 33
S362
P
F
E
F
P
P
T
S
V
Q
W
T
P
E
T
Site 34
T366
P
P
T
S
V
Q
W
T
P
E
T
L
A
A
F
Site 35
T376
T
L
A
A
F
D
L
T
K
R
P
K
D
D
S
Site 36
S383
T
K
R
P
K
D
D
S
T
K
P
K
P
E
E
Site 37
T384
K
R
P
K
D
D
S
T
K
P
K
P
E
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation