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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TAF3
Full Name:
Transcription initiation factor TFIID subunit 3
Alias:
TAF140; TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAFII140; TBP-associated factor 3; Transcription initiation factor TFIID 140 kDa; Transcription initiation factor TFIID 3
Type:
Transcription initiation complex
Mass (Da):
103582
Number AA:
929
UniProt ID:
Q5VWG9
International Prot ID:
IPI00735878
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005669
GO:0005667
GO:0005669
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0051457
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y41
L
T
D
V
L
Q
R
Y
L
Q
Q
L
G
R
G
Site 2
Y52
L
G
R
G
C
H
R
Y
S
E
L
Y
G
R
T
Site 3
S53
G
R
G
C
H
R
Y
S
E
L
Y
G
R
T
D
Site 4
Y56
C
H
R
Y
S
E
L
Y
G
R
T
D
P
I
L
Site 5
Y83
S
L
H
E
L
E
D
Y
I
H
N
I
E
P
V
Site 6
T91
I
H
N
I
E
P
V
T
F
P
H
Q
I
P
S
Site 7
S98
T
F
P
H
Q
I
P
S
F
P
V
S
K
N
N
Site 8
S102
Q
I
P
S
F
P
V
S
K
N
N
V
L
Q
F
Site 9
S114
L
Q
F
P
Q
P
G
S
K
D
A
E
E
R
K
Site 10
Y123
D
A
E
E
R
K
E
Y
I
P
D
Y
L
P
P
Site 11
Y127
R
K
E
Y
I
P
D
Y
L
P
P
I
V
S
S
Site 12
T145
E
E
E
E
Q
V
P
T
D
G
G
T
S
A
E
Site 13
S183
L
G
K
R
P
L
D
S
P
E
A
E
E
L
P
Site 14
S199
M
K
R
P
R
L
L
S
T
K
G
D
T
L
D
Site 15
T200
K
R
P
R
L
L
S
T
K
G
D
T
L
D
V
Site 16
T204
L
L
S
T
K
G
D
T
L
D
V
V
L
L
E
Site 17
S217
L
E
A
R
E
P
L
S
S
I
N
T
Q
K
I
Site 18
S218
E
A
R
E
P
L
S
S
I
N
T
Q
K
I
P
Site 19
T221
E
P
L
S
S
I
N
T
Q
K
I
P
P
M
L
Site 20
S229
Q
K
I
P
P
M
L
S
P
V
H
V
Q
D
S
Site 21
S236
S
P
V
H
V
Q
D
S
T
D
L
A
P
P
S
Site 22
T237
P
V
H
V
Q
D
S
T
D
L
A
P
P
S
P
Site 23
S243
S
T
D
L
A
P
P
S
P
E
P
P
M
L
A
Site 24
S255
M
L
A
P
V
A
K
S
Q
M
P
T
A
K
P
Site 25
T259
V
A
K
S
Q
M
P
T
A
K
P
L
E
T
K
Site 26
S267
A
K
P
L
E
T
K
S
F
T
P
K
T
K
T
Site 27
T269
P
L
E
T
K
S
F
T
P
K
T
K
T
K
T
Site 28
T272
T
K
S
F
T
P
K
T
K
T
K
T
S
S
P
Site 29
T274
S
F
T
P
K
T
K
T
K
T
S
S
P
G
Q
Site 30
S278
K
T
K
T
K
T
S
S
P
G
Q
K
T
K
S
Site 31
T283
T
S
S
P
G
Q
K
T
K
S
P
K
T
A
Q
Site 32
S285
S
P
G
Q
K
T
K
S
P
K
T
A
Q
S
P
Site 33
T288
Q
K
T
K
S
P
K
T
A
Q
S
P
A
M
V
Site 34
S291
K
S
P
K
T
A
Q
S
P
A
M
V
G
S
P
Site 35
S297
Q
S
P
A
M
V
G
S
P
I
R
S
P
K
T
Site 36
S301
M
V
G
S
P
I
R
S
P
K
T
V
S
K
E
Site 37
T304
S
P
I
R
S
P
K
T
V
S
K
E
K
K
S
Site 38
S306
I
R
S
P
K
T
V
S
K
E
K
K
S
P
G
Site 39
S311
T
V
S
K
E
K
K
S
P
G
R
S
K
S
P
Site 40
S315
E
K
K
S
P
G
R
S
K
S
P
K
S
P
K
Site 41
S317
K
S
P
G
R
S
K
S
P
K
S
P
K
S
P
Site 42
S320
G
R
S
K
S
P
K
S
P
K
S
P
K
V
T
Site 43
S323
K
S
P
K
S
P
K
S
P
K
V
T
T
H
I
Site 44
T327
S
P
K
S
P
K
V
T
T
H
I
P
Q
T
P
Site 45
T328
P
K
S
P
K
V
T
T
H
I
P
Q
T
P
V
Site 46
T333
V
T
T
H
I
P
Q
T
P
V
R
P
E
T
P
Site 47
T339
Q
T
P
V
R
P
E
T
P
N
R
T
P
S
A
Site 48
T343
R
P
E
T
P
N
R
T
P
S
A
T
L
S
E
Site 49
S345
E
T
P
N
R
T
P
S
A
T
L
S
E
K
I
Site 50
T347
P
N
R
T
P
S
A
T
L
S
E
K
I
S
K
Site 51
S349
R
T
P
S
A
T
L
S
E
K
I
S
K
E
T
Site 52
S353
A
T
L
S
E
K
I
S
K
E
T
I
Q
V
K
Site 53
T364
I
Q
V
K
Q
I
Q
T
P
P
D
A
G
K
L
Site 54
S373
P
D
A
G
K
L
N
S
E
N
Q
P
K
K
A
Site 55
S410
E
P
D
P
F
E
F
S
S
G
S
E
S
E
G
Site 56
S411
P
D
P
F
E
F
S
S
G
S
E
S
E
G
D
Site 57
S413
P
F
E
F
S
S
G
S
E
S
E
G
D
I
F
Site 58
S415
E
F
S
S
G
S
E
S
E
G
D
I
F
T
S
Site 59
T421
E
S
E
G
D
I
F
T
S
P
K
R
I
S
G
Site 60
S422
S
E
G
D
I
F
T
S
P
K
R
I
S
G
P
Site 61
S427
F
T
S
P
K
R
I
S
G
P
E
C
T
T
P
Site 62
T432
R
I
S
G
P
E
C
T
T
P
K
A
S
T
S
Site 63
T433
I
S
G
P
E
C
T
T
P
K
A
S
T
S
A
Site 64
S439
T
T
P
K
A
S
T
S
A
N
N
F
T
K
S
Site 65
T444
S
T
S
A
N
N
F
T
K
S
G
S
T
P
L
Site 66
S446
S
A
N
N
F
T
K
S
G
S
T
P
L
P
L
Site 67
S448
N
N
F
T
K
S
G
S
T
P
L
P
L
S
G
Site 68
T449
N
F
T
K
S
G
S
T
P
L
P
L
S
G
G
Site 69
S454
G
S
T
P
L
P
L
S
G
G
T
S
S
S
D
Site 70
S458
L
P
L
S
G
G
T
S
S
S
D
N
S
W
T
Site 71
S459
P
L
S
G
G
T
S
S
S
D
N
S
W
T
M
Site 72
S460
L
S
G
G
T
S
S
S
D
N
S
W
T
M
D
Site 73
S463
G
T
S
S
S
D
N
S
W
T
M
D
A
S
I
Site 74
T465
S
S
S
D
N
S
W
T
M
D
A
S
I
D
E
Site 75
S469
N
S
W
T
M
D
A
S
I
D
E
V
V
R
K
Site 76
T481
V
R
K
A
K
L
G
T
P
S
N
M
P
P
N
Site 77
S483
K
A
K
L
G
T
P
S
N
M
P
P
N
F
P
Site 78
Y491
N
M
P
P
N
F
P
Y
I
S
S
P
S
V
S
Site 79
S493
P
P
N
F
P
Y
I
S
S
P
S
V
S
P
P
Site 80
S494
P
N
F
P
Y
I
S
S
P
S
V
S
P
P
T
Site 81
S496
F
P
Y
I
S
S
P
S
V
S
P
P
T
P
E
Site 82
S498
Y
I
S
S
P
S
V
S
P
P
T
P
E
P
L
Site 83
T501
S
P
S
V
S
P
P
T
P
E
P
L
H
K
V
Site 84
T513
H
K
V
Y
E
E
K
T
K
L
P
S
S
V
E
Site 85
S518
E
K
T
K
L
P
S
S
V
E
V
K
K
K
L
Site 86
S553
K
D
K
N
K
D
K
S
K
E
K
D
K
V
K
Site 87
T568
E
K
E
K
D
K
E
T
G
R
E
T
K
Y
P
Site 88
T572
D
K
E
T
G
R
E
T
K
Y
P
W
K
E
F
Site 89
Y574
E
T
G
R
E
T
K
Y
P
W
K
E
F
L
K
Site 90
Y588
K
E
E
E
A
D
P
Y
K
F
K
I
K
E
F
Site 91
S667
E
L
A
L
P
L
F
S
P
A
T
A
S
R
V
Site 92
S755
E
P
V
A
L
A
P
S
P
V
I
P
R
L
T
Site 93
S788
P
E
A
K
P
A
P
S
Q
N
R
P
K
T
P
Site 94
T794
P
S
Q
N
R
P
K
T
P
P
P
A
P
A
P
Site 95
S836
P
S
P
G
P
A
A
S
G
A
S
A
K
A
P
Site 96
T854
V
V
T
E
T
V
S
T
Y
V
I
R
D
E
W
Site 97
Y855
V
T
E
T
V
S
T
Y
V
I
R
D
E
W
G
Site 98
S878
C
N
K
P
D
D
G
S
P
M
I
G
C
D
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation