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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRAMEF16
Full Name:
PRAME family member 16
Alias:
Type:
Mass (Da):
54838
Number AA:
474
UniProt ID:
Q5VWM1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
S
L
Q
S
P
S
R
L
L
E
L
Site 2
T72
P
L
G
S
L
M
K
T
P
H
L
E
T
L
Q
Site 3
S123
W
S
G
A
R
A
L
S
C
S
P
E
A
M
R
Site 4
S125
G
A
R
A
L
S
C
S
P
E
A
M
R
K
R
Site 5
T134
E
A
M
R
K
R
Q
T
V
E
D
Y
P
R
T
Site 6
Y138
K
R
Q
T
V
E
D
Y
P
R
T
G
E
H
Q
Site 7
S158
I
D
L
C
Q
K
E
S
T
L
D
E
C
L
S
Site 8
T159
D
L
C
Q
K
E
S
T
L
D
E
C
L
S
Y
Site 9
Y166
T
L
D
E
C
L
S
Y
L
C
R
W
I
H
Y
Site 10
Y188
C
C
N
K
V
Q
N
Y
S
M
P
T
S
S
F
Site 11
S189
C
N
K
V
Q
N
Y
S
M
P
T
S
S
F
R
Site 12
S193
Q
N
Y
S
M
P
T
S
S
F
R
N
L
L
K
Site 13
S194
N
Y
S
M
P
T
S
S
F
R
N
L
L
K
R
Site 14
Y203
R
N
L
L
K
R
V
Y
P
D
S
I
Q
E
L
Site 15
S206
L
K
R
V
Y
P
D
S
I
Q
E
L
E
I
K
Site 16
S217
L
E
I
K
R
K
C
S
L
N
K
T
G
K
F
Site 17
T221
R
K
C
S
L
N
K
T
G
K
F
A
P
Y
L
Site 18
Y227
K
T
G
K
F
A
P
Y
L
S
Q
M
S
N
L
Site 19
S229
G
K
F
A
P
Y
L
S
Q
M
S
N
L
R
K
Site 20
S232
A
P
Y
L
S
Q
M
S
N
L
R
K
L
F
L
Site 21
Y248
F
G
Y
D
D
E
L
Y
V
S
G
Q
Q
Q
F
Site 22
S250
Y
D
D
E
L
Y
V
S
G
Q
Q
Q
F
V
P
Site 23
Y273
L
Y
Y
P
Q
M
L
Y
I
R
K
I
S
N
I
Site 24
S278
M
L
Y
I
R
K
I
S
N
I
K
E
H
L
E
Site 25
S314
D
Q
D
M
E
C
L
S
Q
Y
P
S
L
S
Q
Site 26
Y316
D
M
E
C
L
S
Q
Y
P
S
L
S
Q
L
K
Site 27
S318
E
C
L
S
Q
Y
P
S
L
S
Q
L
K
E
L
Site 28
S320
L
S
Q
Y
P
S
L
S
Q
L
K
E
L
H
L
Site 29
S364
K
D
C
Q
I
Q
D
S
Q
L
R
V
L
L
P
Site 30
T380
L
S
R
C
S
Q
L
T
T
F
Y
F
R
G
N
Site 31
T381
S
R
C
S
Q
L
T
T
F
Y
F
R
G
N
E
Site 32
Y383
C
S
Q
L
T
T
F
Y
F
R
G
N
E
T
S
Site 33
S390
Y
F
R
G
N
E
T
S
T
N
A
L
K
D
L
Site 34
T440
I
R
A
E
L
M
C
T
L
R
E
V
R
Q
P
Site 35
S459
F
G
P
I
P
C
P
S
C
G
S
W
P
S
E
Site 36
S462
I
P
C
P
S
C
G
S
W
P
S
E
K
V
D
Site 37
S465
P
S
C
G
S
W
P
S
E
K
V
D
F
H
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation