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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KHDRBS2
Full Name:
KH domain-containing, RNA-binding, signal transduction-associated protein 2
Alias:
KHDR2; Sam68-like mammalian protein 1; SLM1; SLM-1
Type:
Cytoplasm, Nucleus protein
Mass (Da):
38927
Number AA:
349
UniProt ID:
Q5VWX1
International Prot ID:
IPI00166708
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003723
GO:0003727
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y6
_
_
M
E
E
E
K
Y
L
P
E
L
M
A
E
Site 2
S16
E
L
M
A
E
K
D
S
L
D
P
S
F
V
H
Site 3
S20
E
K
D
S
L
D
P
S
F
V
H
A
S
R
L
Site 4
S38
E
I
E
K
F
Q
G
S
D
G
K
K
E
D
E
Site 5
Y49
K
E
D
E
E
K
K
Y
L
D
V
I
S
N
K
Site 6
S54
K
K
Y
L
D
V
I
S
N
K
N
I
K
L
S
Site 7
S61
S
N
K
N
I
K
L
S
E
R
V
L
I
P
V
Site 8
S87
L
L
G
P
R
G
N
S
L
K
R
L
Q
E
E
Site 9
T95
L
K
R
L
Q
E
E
T
G
A
K
M
S
I
L
Site 10
S100
E
E
T
G
A
K
M
S
I
L
G
K
G
S
M
Site 11
S106
M
S
I
L
G
K
G
S
M
R
D
K
A
K
E
Site 12
S119
K
E
E
E
L
R
K
S
G
E
A
K
Y
A
H
Site 13
Y124
R
K
S
G
E
A
K
Y
A
H
L
S
D
E
L
Site 14
S128
E
A
K
Y
A
H
L
S
D
E
L
H
V
L
I
Site 15
Y145
F
A
P
P
G
E
A
Y
S
R
M
S
H
A
L
Site 16
S149
G
E
A
Y
S
R
M
S
H
A
L
E
E
I
K
Site 17
Y163
K
K
F
L
V
P
D
Y
N
D
E
I
R
Q
E
Site 18
S176
Q
E
Q
L
R
E
L
S
Y
L
N
G
S
E
D
Site 19
Y177
E
Q
L
R
E
L
S
Y
L
N
G
S
E
D
S
Site 20
S181
E
L
S
Y
L
N
G
S
E
D
S
G
R
G
R
Site 21
S184
Y
L
N
G
S
E
D
S
G
R
G
R
G
I
R
Site 22
T200
R
G
I
R
I
A
P
T
A
P
S
R
G
R
G
Site 23
S203
R
I
A
P
T
A
P
S
R
G
R
G
G
A
I
Site 24
T222
P
P
G
R
G
V
L
T
P
R
G
S
T
V
T
Site 25
T229
T
P
R
G
S
T
V
T
R
G
A
L
P
V
P
Site 26
T244
P
V
A
R
G
V
P
T
P
R
A
R
G
A
P
Site 27
T252
P
R
A
R
G
A
P
T
V
P
G
Y
R
A
P
Site 28
Y256
G
A
P
T
V
P
G
Y
R
A
P
P
P
P
A
Site 29
Y267
P
P
P
A
H
E
A
Y
E
E
Y
G
Y
D
D
Site 30
Y270
A
H
E
A
Y
E
E
Y
G
Y
D
D
G
Y
G
Site 31
Y272
E
A
Y
E
E
Y
G
Y
D
D
G
Y
G
G
E
Site 32
Y276
E
Y
G
Y
D
D
G
Y
G
G
E
Y
D
D
Q
Site 33
Y280
D
D
G
Y
G
G
E
Y
D
D
Q
T
Y
E
T
Site 34
T284
G
G
E
Y
D
D
Q
T
Y
E
T
Y
D
N
S
Site 35
Y285
G
E
Y
D
D
Q
T
Y
E
T
Y
D
N
S
Y
Site 36
Y292
Y
E
T
Y
D
N
S
Y
A
T
Q
T
Q
S
V
Site 37
T296
D
N
S
Y
A
T
Q
T
Q
S
V
P
E
Y
Y
Site 38
S298
S
Y
A
T
Q
T
Q
S
V
P
E
Y
Y
D
Y
Site 39
Y302
Q
T
Q
S
V
P
E
Y
Y
D
Y
G
H
G
V
Site 40
Y303
T
Q
S
V
P
E
Y
Y
D
Y
G
H
G
V
S
Site 41
Y305
S
V
P
E
Y
Y
D
Y
G
H
G
V
S
E
D
Site 42
Y314
H
G
V
S
E
D
A
Y
D
S
Y
A
P
E
E
Site 43
S316
V
S
E
D
A
Y
D
S
Y
A
P
E
E
W
A
Site 44
Y317
S
E
D
A
Y
D
S
Y
A
P
E
E
W
A
T
Site 45
T324
Y
A
P
E
E
W
A
T
T
R
S
S
L
K
A
Site 46
T325
A
P
E
E
W
A
T
T
R
S
S
L
K
A
P
Site 47
S328
E
W
A
T
T
R
S
S
L
K
A
P
P
Q
R
Site 48
S336
L
K
A
P
P
Q
R
S
A
R
G
G
Y
R
E
Site 49
Y341
Q
R
S
A
R
G
G
Y
R
E
H
P
Y
G
R
Site 50
Y346
G
G
Y
R
E
H
P
Y
G
R
Y
_
_
_
_
Site 51
Y349
R
E
H
P
Y
G
R
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation