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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LIPN
Full Name:
Lipase member N
Alias:
Lipase-like abhydrolase domain-containing protein 4
Type:
Mass (Da):
45534
Number AA:
398
UniProt ID:
Q5VXI9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y42
N
T
S
E
I
I
I
Y
N
G
Y
P
S
E
E
Site 2
Y45
E
I
I
I
Y
N
G
Y
P
S
E
E
Y
E
V
Site 3
Y50
N
G
Y
P
S
E
E
Y
E
V
T
T
E
D
G
Site 4
T53
P
S
E
E
Y
E
V
T
T
E
D
G
Y
I
L
Site 5
Y67
L
L
V
N
R
I
P
Y
G
R
T
H
A
R
S
Site 6
S74
Y
G
R
T
H
A
R
S
T
G
P
R
P
V
V
Site 7
T75
G
R
T
H
A
R
S
T
G
P
R
P
V
V
Y
Site 8
Y93
A
L
F
A
D
N
A
Y
W
L
E
N
Y
A
N
Site 9
Y98
N
A
Y
W
L
E
N
Y
A
N
G
S
L
G
F
Site 10
T123
M
G
N
S
R
G
N
T
W
S
R
R
H
K
T
Site 11
S125
N
S
R
G
N
T
W
S
R
R
H
K
T
L
S
Site 12
T130
T
W
S
R
R
H
K
T
L
S
E
T
D
E
K
Site 13
S132
S
R
R
H
K
T
L
S
E
T
D
E
K
F
W
Site 14
T134
R
H
K
T
L
S
E
T
D
E
K
F
W
A
F
Site 15
Y149
S
F
D
E
M
A
K
Y
D
L
P
G
V
I
D
Site 16
T162
I
D
F
I
V
N
K
T
G
Q
E
K
L
Y
F
Site 17
Y168
K
T
G
Q
E
K
L
Y
F
I
G
H
S
L
G
Site 18
Y207
G
P
T
I
S
F
K
Y
P
T
G
I
F
T
R
Site 19
T239
F
F
L
E
D
K
K
T
K
I
A
S
T
K
I
Site 20
Y279
N
Q
S
R
M
D
V
Y
M
S
H
A
P
T
G
Site 21
S281
S
R
M
D
V
Y
M
S
H
A
P
T
G
S
S
Site 22
T285
V
Y
M
S
H
A
P
T
G
S
S
V
H
N
I
Site 23
S288
S
H
A
P
T
G
S
S
V
H
N
I
L
H
I
Site 24
Y299
I
L
H
I
K
Q
L
Y
H
S
D
E
F
R
A
Site 25
Y307
H
S
D
E
F
R
A
Y
D
W
G
N
D
A
D
Site 26
Y319
D
A
D
N
M
K
H
Y
N
Q
S
H
P
P
I
Site 27
Y327
N
Q
S
H
P
P
I
Y
D
L
T
A
M
K
V
Site 28
T330
H
P
P
I
Y
D
L
T
A
M
K
V
P
T
A
Site 29
Y364
P
Q
I
K
S
L
H
Y
F
K
L
L
P
D
W
Site 30
S388
D
A
P
Q
R
M
Y
S
E
I
I
A
L
M
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation