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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LIPK
Full Name:
Lipase member K
Alias:
Lipase-like abhydrolase domain-containing protein 2
Type:
Mass (Da):
45563
Number AA:
399
UniProt ID:
Q5VXJ0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y18
M
L
L
L
G
S
M
Y
G
Y
D
K
K
G
N
Site 2
Y20
L
L
G
S
M
Y
G
Y
D
K
K
G
N
N
A
Site 3
Y44
Q
I
I
S
Y
W
G
Y
P
Y
E
E
Y
D
V
Site 4
Y49
W
G
Y
P
Y
E
E
Y
D
V
T
T
K
D
G
Site 5
T52
P
Y
E
E
Y
D
V
T
T
K
D
G
Y
I
L
Site 6
Y62
D
G
Y
I
L
G
I
Y
R
I
P
H
G
R
G
Site 7
T122
L
G
N
S
R
G
N
T
W
S
R
K
H
L
K
Site 8
S124
N
S
R
G
N
T
W
S
R
K
H
L
K
L
S
Site 9
S131
S
R
K
H
L
K
L
S
P
K
S
P
E
Y
W
Site 10
S134
H
L
K
L
S
P
K
S
P
E
Y
W
A
F
S
Site 11
Y137
L
S
P
K
S
P
E
Y
W
A
F
S
L
D
E
Site 12
S141
S
P
E
Y
W
A
F
S
L
D
E
M
A
K
Y
Site 13
Y148
S
L
D
E
M
A
K
Y
D
L
P
A
T
I
N
Site 14
T161
I
N
F
I
I
E
K
T
G
Q
K
R
L
Y
Y
Site 15
Y167
K
T
G
Q
K
R
L
Y
Y
V
G
H
S
Q
G
Site 16
Y168
T
G
Q
K
R
L
Y
Y
V
G
H
S
Q
G
T
Site 17
S172
R
L
Y
Y
V
G
H
S
Q
G
T
T
I
A
F
Site 18
Y206
A
P
V
V
T
V
K
Y
T
Q
S
P
M
K
K
Site 19
T207
P
V
V
T
V
K
Y
T
Q
S
P
M
K
K
L
Site 20
S209
V
T
V
K
Y
T
Q
S
P
M
K
K
L
T
T
Site 21
T216
S
P
M
K
K
L
T
T
L
S
R
R
V
V
K
Site 22
S263
S
N
F
L
F
T
L
S
G
F
D
P
Q
N
L
Site 23
S273
D
P
Q
N
L
N
M
S
R
L
D
V
Y
L
S
Site 24
Y278
N
M
S
R
L
D
V
Y
L
S
H
N
P
A
G
Site 25
S280
S
R
L
D
V
Y
L
S
H
N
P
A
G
T
S
Site 26
T322
M
M
H
F
H
Q
L
T
P
P
L
Y
N
I
T
Site 27
Y326
H
Q
L
T
P
P
L
Y
N
I
T
K
M
E
V
Site 28
Y364
Q
I
A
N
L
I
Y
Y
K
L
I
P
H
Y
N
Site 29
Y370
Y
Y
K
L
I
P
H
Y
N
H
V
D
F
Y
L
Site 30
Y376
H
Y
N
H
V
D
F
Y
L
G
E
D
A
P
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation