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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C10orf112
Full Name:
MAM and LDL-receptor class A domain-containing protein C10orf112
Alias:
Type:
Mass (Da):
163994
Number AA:
1473
UniProt ID:
Q5VYJ5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
W
Q
V
A
K
L
Q
S
P
T
F
S
Q
T
G
Site 2
T20
V
A
K
L
Q
S
P
T
F
S
Q
T
G
P
G
Site 3
S22
K
L
Q
S
P
T
F
S
Q
T
G
P
G
C
I
Site 4
T57
M
E
N
S
H
D
S
T
V
I
W
R
V
L
Y
Site 5
Y64
T
V
I
W
R
V
L
Y
N
Q
G
K
Q
W
L
Site 6
T111
D
I
R
F
E
N
C
T
L
P
L
P
A
E
S
Site 7
S118
T
L
P
L
P
A
E
S
C
E
G
L
D
H
F
Site 8
T150
V
D
D
C
G
D
R
T
D
E
V
N
C
A
P
Site 9
T181
A
K
D
D
F
D
W
T
R
S
Q
G
P
T
P
Site 10
S183
D
D
F
D
W
T
R
S
Q
G
P
T
P
T
L
Site 11
T187
W
T
R
S
Q
G
P
T
P
T
L
N
T
G
P
Site 12
T189
R
S
Q
G
P
T
P
T
L
N
T
G
P
M
K
Site 13
T192
G
P
T
P
T
L
N
T
G
P
M
K
D
N
T
Site 14
T199
T
G
P
M
K
D
N
T
L
G
T
A
K
G
H
Site 15
Y207
L
G
T
A
K
G
H
Y
L
Y
I
E
S
S
E
Site 16
Y209
T
A
K
G
H
Y
L
Y
I
E
S
S
E
P
Q
Site 17
S213
H
Y
L
Y
I
E
S
S
E
P
Q
A
F
Q
D
Site 18
S221
E
P
Q
A
F
Q
D
S
A
A
L
L
S
P
I
Site 19
T234
P
I
L
N
A
T
D
T
K
G
C
T
F
R
F
Site 20
Y251
H
M
F
G
K
R
I
Y
R
L
A
I
Y
Q
R
Site 21
Y256
R
I
Y
R
L
A
I
Y
Q
R
I
W
S
D
S
Site 22
S261
A
I
Y
Q
R
I
W
S
D
S
R
G
Q
L
L
Site 23
S287
I
R
K
H
L
N
I
S
S
R
Q
P
F
Q
I
Site 24
S288
R
K
H
L
N
I
S
S
R
Q
P
F
Q
I
L
Site 25
Y321
S
F
M
D
C
T
L
Y
P
G
N
L
P
A
D
Site 26
T331
N
L
P
A
D
L
P
T
P
P
E
T
S
V
P
Site 27
T335
D
L
P
T
P
P
E
T
S
V
P
V
T
L
P
Site 28
S336
L
P
T
P
P
E
T
S
V
P
V
T
L
P
P
Site 29
T340
P
E
T
S
V
P
V
T
L
P
P
H
N
C
T
Site 30
Y370
M
Q
K
C
D
F
K
Y
D
C
P
D
K
S
D
Site 31
S380
P
D
K
S
D
E
A
S
C
V
M
E
V
C
S
Site 32
Y397
K
R
S
L
C
K
W
Y
Q
P
I
P
V
H
L
Site 33
S408
P
V
H
L
L
Q
D
S
N
T
F
R
W
G
L
Site 34
T410
H
L
L
Q
D
S
N
T
F
R
W
G
L
G
N
Site 35
S431
G
E
E
N
H
R
P
S
V
D
H
T
Q
N
T
Site 36
T435
H
R
P
S
V
D
H
T
Q
N
T
T
D
G
W
Site 37
Y443
Q
N
T
T
D
G
W
Y
L
Y
A
D
S
S
N
Site 38
Y445
T
T
D
G
W
Y
L
Y
A
D
S
S
N
G
K
Site 39
T456
S
N
G
K
F
G
D
T
A
D
I
L
T
P
I
Site 40
S551
D
I
S
F
Q
D
C
S
P
L
L
S
P
E
R
Site 41
S555
Q
D
C
S
P
L
L
S
P
E
R
K
C
T
D
Site 42
T593
A
D
N
S
D
E
T
T
F
I
C
R
T
S
S
Site 43
S599
T
T
F
I
C
R
T
S
S
G
R
C
D
F
E
Site 44
T641
T
E
P
A
A
D
H
T
L
G
N
S
S
G
H
Site 45
S667
P
M
R
A
A
R
I
S
S
P
V
I
S
K
R
Site 46
S668
M
R
A
A
R
I
S
S
P
V
I
S
K
R
S
Site 47
S672
R
I
S
S
P
V
I
S
K
R
S
K
N
C
K
Site 48
S725
F
W
R
R
E
E
L
S
L
F
G
D
E
D
F
Site 49
S761
V
L
T
E
N
C
L
S
L
H
D
S
V
Q
E
Site 50
S765
N
C
L
S
L
H
D
S
V
Q
E
E
L
A
V
Site 51
Y783
T
G
F
C
P
L
G
Y
R
E
C
H
N
G
K
Site 52
T808
V
D
N
C
G
D
N
T
D
E
N
E
C
G
S
Site 53
S845
L
G
V
G
S
H
Q
S
L
R
P
P
K
D
H
Site 54
T853
L
R
P
P
K
D
H
T
L
G
N
E
N
A
I
Site 55
Y868
L
L
M
R
R
H
K
Y
P
I
R
S
V
N
L
Site 56
T910
L
S
V
P
N
E
N
T
F
G
S
S
D
H
T
Site 57
T941
D
K
A
H
F
R
S
T
M
W
R
E
S
S
A
Site 58
S946
R
S
T
M
W
R
E
S
S
A
A
C
T
M
S
Site 59
S947
S
T
M
W
R
E
S
S
A
A
C
T
M
S
F
Site 60
S985
R
A
P
N
P
V
L
S
G
S
P
T
I
P
R
Site 61
S987
P
N
P
V
L
S
G
S
P
T
I
P
R
Q
G
Site 62
T989
P
V
L
S
G
S
P
T
I
P
R
Q
G
S
Q
Site 63
S995
P
T
I
P
R
Q
G
S
Q
Q
L
G
G
W
R
Site 64
S1005
L
G
G
W
R
G
G
S
A
R
H
R
A
R
A
Site 65
S1023
P
E
C
P
R
G
R
S
A
L
L
K
G
P
P
Site 66
S1038
Q
E
K
P
N
R
R
S
A
L
L
S
V
G
E
Site 67
S1042
N
R
R
S
A
L
L
S
V
G
E
I
S
E
L
Site 68
Y1072
A
S
H
L
L
C
D
Y
K
P
D
C
S
D
R
Site 69
S1077
C
D
Y
K
P
D
C
S
D
R
S
D
E
A
H
Site 70
S1080
K
P
D
C
S
D
R
S
D
E
A
H
C
A
H
Site 71
Y1088
D
E
A
H
C
A
H
Y
T
S
T
T
G
S
C
Site 72
S1094
H
Y
T
S
T
T
G
S
C
N
F
E
T
S
S
Site 73
T1105
E
T
S
S
G
N
W
T
T
A
C
S
L
T
Q
Site 74
S1109
G
N
W
T
T
A
C
S
L
T
Q
D
S
E
D
Site 75
S1135
A
K
A
L
I
P
D
S
D
H
T
P
G
S
G
Site 76
T1138
L
I
P
D
S
D
H
T
P
G
S
G
Q
H
F
Site 77
S1141
D
S
D
H
T
P
G
S
G
Q
H
F
L
Y
V
Site 78
Y1147
G
S
G
Q
H
F
L
Y
V
N
S
S
G
S
K
Site 79
S1151
H
F
L
Y
V
N
S
S
G
S
K
E
G
S
V
Site 80
S1153
L
Y
V
N
S
S
G
S
K
E
G
S
V
A
R
Site 81
S1157
S
S
G
S
K
E
G
S
V
A
R
I
T
T
S
Site 82
T1162
E
G
S
V
A
R
I
T
T
S
K
S
F
P
A
Site 83
T1163
G
S
V
A
R
I
T
T
S
K
S
F
P
A
S
Site 84
S1164
S
V
A
R
I
T
T
S
K
S
F
P
A
S
L
Site 85
S1166
A
R
I
T
T
S
K
S
F
P
A
S
L
G
M
Site 86
S1170
T
S
K
S
F
P
A
S
L
G
M
C
T
V
R
Site 87
Y1218
N
K
R
T
G
W
T
Y
G
S
V
P
L
S
S
Site 88
S1220
R
T
G
W
T
Y
G
S
V
P
L
S
S
N
S
Site 89
S1224
T
Y
G
S
V
P
L
S
S
N
S
P
F
K
V
Site 90
S1225
Y
G
S
V
P
L
S
S
N
S
P
F
K
V
A
Site 91
S1227
S
V
P
L
S
S
N
S
P
F
K
V
A
F
E
Site 92
S1267
G
P
V
P
V
Q
P
S
P
C
E
A
D
Q
F
Site 93
S1286
T
L
Q
C
V
P
L
S
G
K
C
D
G
H
E
Site 94
S1307
D
E
M
D
C
P
L
S
P
T
P
P
L
C
S
Site 95
T1309
M
D
C
P
L
S
P
T
P
P
L
C
S
N
M
Site 96
S1314
S
P
T
P
P
L
C
S
N
M
E
F
P
C
S
Site 97
S1321
S
N
M
E
F
P
C
S
T
D
E
C
I
P
S
Site 98
T1322
N
M
E
F
P
C
S
T
D
E
C
I
P
S
L
Site 99
S1348
N
E
D
E
L
I
C
S
N
K
S
C
S
N
G
Site 100
S1364
L
V
C
A
S
S
N
S
C
I
P
A
H
Q
R
Site 101
S1387
D
F
Q
L
D
E
S
S
C
S
D
T
W
T
L
Site 102
S1389
Q
L
D
E
S
S
C
S
D
T
W
T
L
L
G
Site 103
T1391
D
E
S
S
C
S
D
T
W
T
L
L
G
I
G
Site 104
T1424
R
K
V
P
I
R
K
T
E
G
S
G
N
C
A
Site 105
S1427
P
I
R
K
T
E
G
S
G
N
C
A
F
V
N
Site 106
Y1437
C
A
F
V
N
P
V
Y
G
N
W
S
N
P
E
Site 107
T1446
N
W
S
N
P
E
K
T
E
S
S
V
Y
S
F
Site 108
S1448
S
N
P
E
K
T
E
S
S
V
Y
S
F
S
N
Site 109
S1449
N
P
E
K
T
E
S
S
V
Y
S
F
S
N
P
Site 110
Y1451
E
K
T
E
S
S
V
Y
S
F
S
N
P
L
Y
Site 111
S1452
K
T
E
S
S
V
Y
S
F
S
N
P
L
Y
G
Site 112
S1454
E
S
S
V
Y
S
F
S
N
P
L
Y
G
T
T
Site 113
Y1458
Y
S
F
S
N
P
L
Y
G
T
T
S
G
S
L
Site 114
T1460
F
S
N
P
L
Y
G
T
T
S
G
S
L
E
T
Site 115
S1462
N
P
L
Y
G
T
T
S
G
S
L
E
T
L
S
Site 116
S1464
L
Y
G
T
T
S
G
S
L
E
T
L
S
H
H
Site 117
S1469
S
G
S
L
E
T
L
S
H
H
L
K
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation