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Updated November 2019
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Protein Info
Short Name:
FOXB2
Full Name:
Forkhead box protein B2
Alias:
Type:
Mass (Da):
45581
Number AA:
432
UniProt ID:
Q5VYV0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
P
R
P
G
K
S
S
Y
S
D
Q
K
P
P
Site 2
Y9
P
R
P
G
K
S
S
Y
S
D
Q
K
P
P
Y
Site 3
S10
R
P
G
K
S
S
Y
S
D
Q
K
P
P
Y
S
Site 4
Y16
Y
S
D
Q
K
P
P
Y
S
Y
I
S
L
T
A
Site 5
S17
S
D
Q
K
P
P
Y
S
Y
I
S
L
T
A
M
Site 6
Y49
F
I
M
E
R
F
P
Y
Y
R
E
H
T
Q
R
Site 7
Y50
I
M
E
R
F
P
Y
Y
R
E
H
T
Q
R
W
Site 8
S85
P
D
Q
P
G
K
G
S
F
W
A
L
H
P
D
Site 9
S101
G
D
M
F
E
N
G
S
F
L
R
R
R
K
R
Site 10
T117
K
V
L
R
A
D
H
T
H
L
H
A
G
S
T
Site 11
S126
L
H
A
G
S
T
K
S
A
P
G
A
G
P
G
Site 12
T186
Y
F
H
Q
Q
P
P
T
A
P
Q
P
P
P
H
Site 13
S196
Q
P
P
P
H
L
P
S
Q
P
P
Q
Q
P
P
Site 14
S206
P
Q
Q
P
P
Q
Q
S
Q
P
Q
Q
P
S
H
Site 15
S212
Q
S
Q
P
Q
Q
P
S
H
P
G
K
M
Q
E
Site 16
Y247
R
L
S
Q
F
P
P
Y
G
L
G
S
A
A
A
Site 17
Y280
E
N
I
I
G
R
D
Y
K
G
V
L
Q
A
G
Site 18
S354
P
V
K
S
L
C
H
S
A
S
Q
S
L
P
A
Site 19
S356
K
S
L
C
H
S
A
S
Q
S
L
P
A
M
P
Site 20
T383
S
A
L
Q
P
G
L
T
V
P
A
A
S
Q
Q
Site 21
S388
G
L
T
V
P
A
A
S
Q
Q
P
P
A
P
S
Site 22
S395
S
Q
Q
P
P
A
P
S
T
V
C
S
A
A
A
Site 23
T396
Q
Q
P
P
A
P
S
T
V
C
S
A
A
A
A
Site 24
S417
L
E
P
T
A
P
T
S
A
E
S
K
G
G
S
Site 25
S420
T
A
P
T
S
A
E
S
K
G
G
S
L
H
S
Site 26
S424
S
A
E
S
K
G
G
S
L
H
S
V
L
V
H
Site 27
S427
S
K
G
G
S
L
H
S
V
L
V
H
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation