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Updated November 2019
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Protein Info
Short Name:
KIAA1614
Full Name:
Uncharacterized protein KIAA1614
Alias:
Type:
Mass (Da):
126604
Number AA:
1190
UniProt ID:
Q5VZ46
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
A
A
K
P
A
G
G
S
P
Q
G
P
K
T
G
Site 2
T21
G
S
P
Q
G
P
K
T
G
S
G
T
A
S
P
Site 3
S23
P
Q
G
P
K
T
G
S
G
T
A
S
P
V
E
Site 4
T25
G
P
K
T
G
S
G
T
A
S
P
V
E
G
T
Site 5
S27
K
T
G
S
G
T
A
S
P
V
E
G
T
S
A
Site 6
S33
A
S
P
V
E
G
T
S
A
V
E
W
S
G
P
Site 7
T61
P
C
P
Q
E
N
R
T
S
S
P
M
A
P
Q
Site 8
S62
C
P
Q
E
N
R
T
S
S
P
M
A
P
Q
P
Site 9
S63
P
Q
E
N
R
T
S
S
P
M
A
P
Q
P
P
Site 10
S81
G
V
Q
L
Q
G
P
S
V
L
E
S
K
V
R
Site 11
S85
Q
G
P
S
V
L
E
S
K
V
R
A
L
K
E
Site 12
T95
R
A
L
K
E
K
M
T
V
A
K
Q
G
V
S
Site 13
S102
T
V
A
K
Q
G
V
S
P
C
S
A
S
Q
E
Site 14
S105
K
Q
G
V
S
P
C
S
A
S
Q
E
W
S
S
Site 15
S107
G
V
S
P
C
S
A
S
Q
E
W
S
S
P
K
Site 16
S111
C
S
A
S
Q
E
W
S
S
P
K
K
P
Q
C
Site 17
S112
S
A
S
Q
E
W
S
S
P
K
K
P
Q
C
R
Site 18
T128
G
K
A
G
R
A
G
T
P
S
E
G
S
F
L
Site 19
S130
A
G
R
A
G
T
P
S
E
G
S
F
L
P
G
Site 20
S155
P
D
G
Q
L
D
G
S
I
N
E
E
Q
P
A
Site 21
Y179
P
P
A
P
G
R
E
Y
C
N
R
G
S
P
W
Site 22
S184
R
E
Y
C
N
R
G
S
P
W
P
P
E
A
E
Site 23
T193
W
P
P
E
A
E
W
T
L
P
D
H
D
R
G
Site 24
S206
R
G
P
L
L
G
P
S
S
L
Q
Q
S
P
I
Site 25
S207
G
P
L
L
G
P
S
S
L
Q
Q
S
P
I
H
Site 26
S211
G
P
S
S
L
Q
Q
S
P
I
H
G
V
T
P
Site 27
T217
Q
S
P
I
H
G
V
T
P
G
R
P
G
G
P
Site 28
S235
N
K
I
I
H
I
P
S
P
R
T
G
R
S
Y
Site 29
T238
I
H
I
P
S
P
R
T
G
R
S
Y
P
F
P
Site 30
S241
P
S
P
R
T
G
R
S
Y
P
F
P
D
G
V
Site 31
Y242
S
P
R
T
G
R
S
Y
P
F
P
D
G
V
V
Site 32
S256
V
T
E
A
D
L
D
S
T
S
L
T
S
E
E
Site 33
S258
E
A
D
L
D
S
T
S
L
T
S
E
E
V
F
Site 34
T260
D
L
D
S
T
S
L
T
S
E
E
V
F
V
P
Site 35
S289
E
A
L
G
A
G
S
S
V
L
S
L
S
D
R
Site 36
S292
G
A
G
S
S
V
L
S
L
S
D
R
V
E
R
Site 37
S294
G
S
S
V
L
S
L
S
D
R
V
E
R
N
R
Site 38
S314
M
L
N
V
S
G
Q
S
P
R
K
V
G
T
P
Site 39
T320
Q
S
P
R
K
V
G
T
P
A
W
T
P
S
W
Site 40
T324
K
V
G
T
P
A
W
T
P
S
W
D
T
A
A
Site 41
T329
A
W
T
P
S
W
D
T
A
A
P
E
R
P
V
Site 42
S343
V
G
D
V
D
W
A
S
G
T
S
L
Q
D
S
Site 43
S346
V
D
W
A
S
G
T
S
L
Q
D
S
G
Q
N
Site 44
S350
S
G
T
S
L
Q
D
S
G
Q
N
R
T
V
G
Site 45
T355
Q
D
S
G
Q
N
R
T
V
G
P
N
P
E
P
Site 46
S365
P
N
P
E
P
V
L
S
P
R
H
E
E
A
T
Site 47
T372
S
P
R
H
E
E
A
T
H
L
L
Q
R
A
R
Site 48
T384
R
A
R
M
K
A
R
T
R
P
L
R
A
S
H
Site 49
S390
R
T
R
P
L
R
A
S
H
D
I
V
P
T
I
Site 50
S407
G
S
R
D
G
H
R
S
P
A
R
D
P
R
T
Site 51
T414
S
P
A
R
D
P
R
T
T
P
A
C
R
D
S
Site 52
T415
P
A
R
D
P
R
T
T
P
A
C
R
D
S
L
Site 53
S421
T
T
P
A
C
R
D
S
L
Q
N
G
H
T
S
Site 54
T427
D
S
L
Q
N
G
H
T
S
D
S
S
S
G
E
Site 55
S428
S
L
Q
N
G
H
T
S
D
S
S
S
G
E
S
Site 56
S430
Q
N
G
H
T
S
D
S
S
S
G
E
S
S
G
Site 57
S431
N
G
H
T
S
D
S
S
S
G
E
S
S
G
G
Site 58
S432
G
H
T
S
D
S
S
S
G
E
S
S
G
G
H
Site 59
S435
S
D
S
S
S
G
E
S
S
G
G
H
R
P
R
Site 60
S436
D
S
S
S
G
E
S
S
G
G
H
R
P
R
R
Site 61
S446
H
R
P
R
R
G
P
S
P
S
H
V
R
F
E
Site 62
S448
P
R
R
G
P
S
P
S
H
V
R
F
E
D
E
Site 63
S456
H
V
R
F
E
D
E
S
A
R
E
A
E
F
R
Site 64
S477
Q
R
Q
R
Q
V
L
S
T
V
L
Q
A
A
D
Site 65
T478
R
Q
R
Q
V
L
S
T
V
L
Q
A
A
D
Q
Site 66
S490
A
D
Q
G
P
L
R
S
K
P
D
L
A
D
Y
Site 67
Y497
S
K
P
D
L
A
D
Y
I
N
G
A
P
R
L
Site 68
T511
L
R
D
A
G
Q
G
T
F
H
R
L
V
G
S
Site 69
S518
T
F
H
R
L
V
G
S
L
D
R
R
G
H
P
Site 70
S532
P
A
P
P
A
P
G
S
E
R
R
C
Q
A
C
Site 71
T559
K
A
P
P
V
P
R
T
L
Q
E
L
Q
A
A
Site 72
T602
R
E
T
H
I
G
D
T
V
C
P
A
E
V
D
Site 73
S610
V
C
P
A
E
V
D
S
A
L
D
S
T
D
N
Site 74
S614
E
V
D
S
A
L
D
S
T
D
N
S
D
N
C
Site 75
T615
V
D
S
A
L
D
S
T
D
N
S
D
N
C
R
Site 76
S618
A
L
D
S
T
D
N
S
D
N
C
R
T
D
S
Site 77
S625
S
D
N
C
R
T
D
S
E
E
A
G
T
S
Q
Site 78
T630
T
D
S
E
E
A
G
T
S
Q
A
G
W
A
C
Site 79
S631
D
S
E
E
A
G
T
S
Q
A
G
W
A
C
G
Site 80
T640
A
G
W
A
C
G
R
T
Q
G
S
S
P
R
L
Site 81
S643
A
C
G
R
T
Q
G
S
S
P
R
L
R
L
R
Site 82
S644
C
G
R
T
Q
G
S
S
P
R
L
R
L
R
G
Site 83
S652
P
R
L
R
L
R
G
S
R
P
R
G
H
R
W
Site 84
S660
R
P
R
G
H
R
W
S
K
K
A
E
A
E
L
Site 85
T696
V
K
E
G
R
G
H
T
P
E
G
T
L
F
L
Site 86
S718
D
L
E
L
K
R
V
S
L
G
P
Q
W
Q
P
Site 87
S731
Q
P
G
P
G
L
G
S
H
Q
P
H
P
L
D
Site 88
S739
H
Q
P
H
P
L
D
S
R
T
P
C
R
T
A
Site 89
T741
P
H
P
L
D
S
R
T
P
C
R
T
A
Y
A
Site 90
T745
D
S
R
T
P
C
R
T
A
Y
A
T
T
A
P
Site 91
Y747
R
T
P
C
R
T
A
Y
A
T
T
A
P
M
T
Site 92
T749
P
C
R
T
A
Y
A
T
T
A
P
M
T
P
E
Site 93
T754
Y
A
T
T
A
P
M
T
P
E
S
S
G
P
G
Site 94
S757
T
A
P
M
T
P
E
S
S
G
P
G
G
Q
A
Site 95
S758
A
P
M
T
P
E
S
S
G
P
G
G
Q
A
Q
Site 96
T767
P
G
G
Q
A
Q
V
T
E
S
H
E
S
L
E
Site 97
S769
G
Q
A
Q
V
T
E
S
H
E
S
L
E
I
V
Site 98
S772
Q
V
T
E
S
H
E
S
L
E
I
V
S
P
S
Site 99
S777
H
E
S
L
E
I
V
S
P
S
S
L
Q
Q
S
Site 100
S779
S
L
E
I
V
S
P
S
S
L
Q
Q
S
H
A
Site 101
S780
L
E
I
V
S
P
S
S
L
Q
Q
S
H
A
E
Site 102
S784
S
P
S
S
L
Q
Q
S
H
A
E
P
S
A
P
Site 103
T809
C
P
E
G
W
A
P
T
P
P
P
S
R
K
T
Site 104
S813
W
A
P
T
P
P
P
S
R
K
T
T
S
P
V
Site 105
T816
T
P
P
P
S
R
K
T
T
S
P
V
S
H
R
Site 106
T817
P
P
P
S
R
K
T
T
S
P
V
S
H
R
K
Site 107
S818
P
P
S
R
K
T
T
S
P
V
S
H
R
K
A
Site 108
S821
R
K
T
T
S
P
V
S
H
R
K
A
A
L
A
Site 109
T837
L
L
R
L
G
D
Q
T
E
P
V
G
I
P
R
Site 110
S847
V
G
I
P
R
P
P
S
R
S
A
V
L
R
T
Site 111
S849
I
P
R
P
P
S
R
S
A
V
L
R
T
C
E
Site 112
T854
S
R
S
A
V
L
R
T
C
E
L
P
P
S
Q
Site 113
S860
R
T
C
E
L
P
P
S
Q
T
Q
P
S
R
P
Site 114
T862
C
E
L
P
P
S
Q
T
Q
P
S
R
P
Q
V
Site 115
S865
P
P
S
Q
T
Q
P
S
R
P
Q
V
R
H
P
Site 116
S877
R
H
P
L
L
A
L
S
T
N
N
C
N
N
S
Site 117
S884
S
T
N
N
C
N
N
S
A
P
R
G
L
Q
E
Site 118
S908
R
V
E
R
G
P
C
S
R
E
P
E
P
P
L
Site 119
S918
P
E
P
P
L
E
N
S
R
D
G
G
P
Q
G
Site 120
T941
T
I
N
S
T
G
I
T
L
S
L
S
S
E
E
Site 121
S943
N
S
T
G
I
T
L
S
L
S
S
E
E
S
E
Site 122
S945
T
G
I
T
L
S
L
S
S
E
E
S
E
S
S
Site 123
S946
G
I
T
L
S
L
S
S
E
E
S
E
S
S
K
Site 124
S949
L
S
L
S
S
E
E
S
E
S
S
K
E
S
E
Site 125
S951
L
S
S
E
E
S
E
S
S
K
E
S
E
G
S
Site 126
S952
S
S
E
E
S
E
S
S
K
E
S
E
G
S
L
Site 127
S955
E
S
E
S
S
K
E
S
E
G
S
L
Q
R
T
Site 128
S958
S
S
K
E
S
E
G
S
L
Q
R
T
G
S
G
Site 129
T962
S
E
G
S
L
Q
R
T
G
S
G
S
G
G
H
Site 130
S964
G
S
L
Q
R
T
G
S
G
S
G
G
H
V
L
Site 131
S966
L
Q
R
T
G
S
G
S
G
G
H
V
L
S
R
Site 132
S972
G
S
G
G
H
V
L
S
R
A
S
A
G
A
G
Site 133
S975
G
H
V
L
S
R
A
S
A
G
A
G
T
G
P
Site 134
T980
R
A
S
A
G
A
G
T
G
P
G
S
P
S
A
Site 135
S984
G
A
G
T
G
P
G
S
P
S
A
A
P
L
D
Site 136
S986
G
T
G
P
G
S
P
S
A
A
P
L
D
Q
N
Site 137
S997
L
D
Q
N
K
K
R
S
S
S
I
A
S
T
L
Site 138
S998
D
Q
N
K
K
R
S
S
S
I
A
S
T
L
G
Site 139
S999
Q
N
K
K
R
S
S
S
I
A
S
T
L
G
L
Site 140
S1002
K
R
S
S
S
I
A
S
T
L
G
L
K
K
L
Site 141
S1011
L
G
L
K
K
L
F
S
A
L
G
Q
S
S
R
Site 142
S1016
L
F
S
A
L
G
Q
S
S
R
P
K
L
G
K
Site 143
S1017
F
S
A
L
G
Q
S
S
R
P
K
L
G
K
S
Site 144
S1024
S
R
P
K
L
G
K
S
R
S
Y
S
V
E
Q
Site 145
S1026
P
K
L
G
K
S
R
S
Y
S
V
E
Q
L
Q
Site 146
Y1027
K
L
G
K
S
R
S
Y
S
V
E
Q
L
Q
P
Site 147
S1028
L
G
K
S
R
S
Y
S
V
E
Q
L
Q
P
A
Site 148
S1041
P
A
P
P
G
L
T
S
Q
S
R
A
P
S
L
Site 149
S1043
P
P
G
L
T
S
Q
S
R
A
P
S
L
Q
S
Site 150
S1047
T
S
Q
S
R
A
P
S
L
Q
S
L
H
P
V
Site 151
S1050
S
R
A
P
S
L
Q
S
L
H
P
V
S
P
S
Site 152
S1055
L
Q
S
L
H
P
V
S
P
S
H
Q
R
R
K
Site 153
S1065
H
Q
R
R
K
A
A
S
F
Q
N
L
H
S
L
Site 154
S1071
A
S
F
Q
N
L
H
S
L
L
S
S
K
G
D
Site 155
S1074
Q
N
L
H
S
L
L
S
S
K
G
D
R
S
S
Site 156
S1075
N
L
H
S
L
L
S
S
K
G
D
R
S
S
L
Site 157
S1080
L
S
S
K
G
D
R
S
S
L
Y
L
V
A
G
Site 158
S1081
S
S
K
G
D
R
S
S
L
Y
L
V
A
G
P
Site 159
Y1083
K
G
D
R
S
S
L
Y
L
V
A
G
P
G
D
Site 160
S1092
V
A
G
P
G
D
H
S
A
A
G
R
P
A
K
Site 161
T1100
A
A
G
R
P
A
K
T
S
P
R
R
A
L
S
Site 162
S1101
A
G
R
P
A
K
T
S
P
R
R
A
L
S
V
Site 163
S1107
T
S
P
R
R
A
L
S
V
E
D
V
G
A
P
Site 164
S1115
V
E
D
V
G
A
P
S
L
A
R
T
V
G
R
Site 165
S1132
E
V
F
P
D
G
T
S
Q
L
Q
L
Q
R
S
Site 166
S1139
S
Q
L
Q
L
Q
R
S
P
G
G
T
F
G
F
Site 167
S1150
T
F
G
F
C
V
A
S
G
N
G
R
P
D
S
Site 168
S1157
S
G
N
G
R
P
D
S
G
M
P
S
P
L
P
Site 169
S1161
R
P
D
S
G
M
P
S
P
L
P
Q
P
H
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation