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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LIPJ
Full Name:
Lipase member J
Alias:
Lipase-like abhydrolase domain-containing protein 1
Type:
Mass (Da):
42374
Number AA:
366
UniProt ID:
Q5W064
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
Q
I
I
S
Y
W
G
Y
P
D
E
E
Y
D
I
Site 2
Y17
W
G
Y
P
D
E
E
Y
D
I
V
T
E
D
G
Site 3
T21
D
E
E
Y
D
I
V
T
E
D
G
Y
I
L
G
Site 4
Y30
D
G
Y
I
L
G
L
Y
R
I
P
Y
W
R
T
Site 5
Y34
L
G
L
Y
R
I
P
Y
W
R
T
D
N
N
K
Site 6
S58
L
Q
H
G
L
L
T
S
A
S
S
W
I
S
N
Site 7
S64
T
S
A
S
S
W
I
S
N
L
P
N
N
S
L
Site 8
T91
M
G
N
S
R
G
N
T
W
S
R
K
H
L
Y
Site 9
S93
N
S
R
G
N
T
W
S
R
K
H
L
Y
L
E
Site 10
Y98
T
W
S
R
K
H
L
Y
L
E
T
S
S
K
E
Site 11
S102
K
H
L
Y
L
E
T
S
S
K
E
F
W
A
F
Site 12
Y117
S
F
D
E
M
A
K
Y
D
L
P
A
S
I
D
Site 13
S122
A
K
Y
D
L
P
A
S
I
D
F
T
V
K
Q
Site 14
T126
L
P
A
S
I
D
F
T
V
K
Q
T
R
Q
E
Site 15
Y137
T
R
Q
E
E
I
F
Y
V
G
H
S
Q
G
T
Site 16
Y175
A
P
V
F
S
T
K
Y
L
K
S
P
L
I
R
Site 17
S178
F
S
T
K
Y
L
K
S
P
L
I
R
M
T
Y
Site 18
T184
K
S
P
L
I
R
M
T
Y
K
W
K
S
I
V
Site 19
Y185
S
P
L
I
R
M
T
Y
K
W
K
S
I
V
M
Site 20
T204
N
K
D
F
L
P
K
T
S
F
K
K
F
V
G
Site 21
S205
K
D
F
L
P
K
T
S
F
K
K
F
V
G
S
Site 22
S242
D
P
K
N
L
N
M
S
R
L
D
V
Y
F
S
Site 23
Y247
N
M
S
R
L
D
V
Y
F
S
H
N
P
A
G
Site 24
S249
S
R
L
D
V
Y
F
S
H
N
P
A
G
T
S
Site 25
Y275
N
S
T
H
L
K
A
Y
D
W
G
S
P
D
L
Site 26
S279
L
K
A
Y
D
W
G
S
P
D
L
N
L
V
H
Site 27
Y287
P
D
L
N
L
V
H
Y
N
Q
T
T
S
P
L
Site 28
Y295
N
Q
T
T
S
P
L
Y
N
M
T
N
M
N
V
Site 29
S311
T
A
I
W
N
G
K
S
D
L
L
A
D
P
E
Site 30
Y332
S
E
I
T
N
H
I
Y
Y
K
T
I
S
Y
Y
Site 31
Y333
E
I
T
N
H
I
Y
Y
K
T
I
S
Y
Y
N
Site 32
Y338
I
Y
Y
K
T
I
S
Y
Y
N
H
I
D
S
L
Site 33
Y339
Y
Y
K
T
I
S
Y
Y
N
H
I
D
S
L
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation