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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FLJ32682
Full Name:
Protein FAM194B
Alias:
Family with sequence similarity 194, member B; LOC220081
Type:
Mass (Da):
81690
Number AA:
UniProt ID:
Q5W0A0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
S
A
E
N
N
Q
L
S
G
A
S
P
P
H
P
Site 2
S12
N
N
Q
L
S
G
A
S
P
P
H
P
P
T
T
Site 3
T18
A
S
P
P
H
P
P
T
T
P
Q
Y
S
T
Q
Site 4
T19
S
P
P
H
P
P
T
T
P
Q
Y
S
T
Q
N
Site 5
Y22
H
P
P
T
T
P
Q
Y
S
T
Q
N
L
P
S
Site 6
S23
P
P
T
T
P
Q
Y
S
T
Q
N
L
P
S
E
Site 7
T34
L
P
S
E
K
E
D
T
E
V
E
L
D
E
E
Site 8
S42
E
V
E
L
D
E
E
S
L
Q
D
E
S
P
F
Site 9
S47
E
E
S
L
Q
D
E
S
P
F
S
P
E
G
E
Site 10
S50
L
Q
D
E
S
P
F
S
P
E
G
E
S
L
E
Site 11
S55
P
F
S
P
E
G
E
S
L
E
D
K
E
Y
L
Site 12
Y61
E
S
L
E
D
K
E
Y
L
E
E
E
E
D
L
Site 13
Y73
E
D
L
E
E
E
E
Y
L
G
K
E
E
Y
L
Site 14
Y79
E
Y
L
G
K
E
E
Y
L
K
E
E
E
Y
L
Site 15
Y85
E
Y
L
K
E
E
E
Y
L
G
K
E
E
H
L
Site 16
Y97
E
H
L
E
E
E
E
Y
L
E
K
A
G
Y
L
Site 17
Y103
E
Y
L
E
K
A
G
Y
L
E
E
E
E
Y
I
Site 18
Y109
G
Y
L
E
E
E
E
Y
I
E
E
E
E
Y
L
Site 19
Y115
E
Y
I
E
E
E
E
Y
L
G
K
E
G
Y
L
Site 20
Y121
E
Y
L
G
K
E
G
Y
L
E
E
E
E
Y
L
Site 21
Y127
G
Y
L
E
E
E
E
Y
L
G
K
E
E
H
L
Site 22
Y139
E
H
L
E
E
E
E
Y
L
G
K
E
G
Y
L
Site 23
Y145
E
Y
L
G
K
E
G
Y
L
E
K
E
D
Y
I
Site 24
Y151
G
Y
L
E
K
E
D
Y
I
E
E
V
D
Y
L
Site 25
Y157
D
Y
I
E
E
V
D
Y
L
G
K
K
A
Y
L
Site 26
Y163
D
Y
L
G
K
K
A
Y
L
E
E
E
E
Y
L
Site 27
Y169
A
Y
L
E
E
E
E
Y
L
G
K
K
S
Y
L
Site 28
S174
E
E
Y
L
G
K
K
S
Y
L
E
E
E
K
A
Site 29
Y175
E
Y
L
G
K
K
S
Y
L
E
E
E
K
A
L
Site 30
S217
Y
L
K
E
P
K
A
S
Y
S
S
Q
T
M
L
Site 31
S220
E
P
K
A
S
Y
S
S
Q
T
M
L
L
R
D
Site 32
S230
M
L
L
R
D
A
R
S
P
D
A
G
P
S
Q
Site 33
S236
R
S
P
D
A
G
P
S
Q
V
T
T
F
L
T
Site 34
S252
P
L
T
F
A
T
P
S
P
V
S
E
S
A
T
Site 35
S255
F
A
T
P
S
P
V
S
E
S
A
T
E
S
S
Site 36
S257
T
P
S
P
V
S
E
S
A
T
E
S
S
E
L
Site 37
T259
S
P
V
S
E
S
A
T
E
S
S
E
L
L
L
Site 38
S262
S
E
S
A
T
E
S
S
E
L
L
L
T
L
Y
Site 39
T267
E
S
S
E
L
L
L
T
L
Y
R
R
S
Q
A
Site 40
Y269
S
E
L
L
L
T
L
Y
R
R
S
Q
A
S
Q
Site 41
S272
L
L
T
L
Y
R
R
S
Q
A
S
Q
T
D
W
Site 42
Y281
A
S
Q
T
D
W
C
Y
D
R
T
A
V
K
S
Site 43
T284
T
D
W
C
Y
D
R
T
A
V
K
S
L
K
S
Site 44
S288
Y
D
R
T
A
V
K
S
L
K
S
K
S
E
T
Site 45
S291
T
A
V
K
S
L
K
S
K
S
E
T
E
Q
E
Site 46
S293
V
K
S
L
K
S
K
S
E
T
E
Q
E
T
T
Site 47
T295
S
L
K
S
K
S
E
T
E
Q
E
T
T
T
K
Site 48
T300
S
E
T
E
Q
E
T
T
T
K
L
A
P
E
E
Site 49
T311
A
P
E
E
H
V
N
T
K
V
Q
Q
K
K
E
Site 50
T335
E
N
F
W
D
G
I
T
D
E
S
I
D
K
L
Site 51
S338
W
D
G
I
T
D
E
S
I
D
K
L
E
V
E
Site 52
Y356
E
N
F
L
N
S
S
Y
Q
T
V
F
K
T
I
Site 53
T382
E
D
F
D
I
P
L
T
K
L
L
E
S
E
N
Site 54
T421
R
R
E
A
Q
K
L
T
E
M
T
S
F
T
F
Site 55
S425
Q
K
L
T
E
M
T
S
F
T
F
H
L
M
S
Site 56
T427
L
T
E
M
T
S
F
T
F
H
L
M
S
K
P
Site 57
T435
F
H
L
M
S
K
P
T
P
E
K
P
E
T
E
Site 58
T441
P
T
P
E
K
P
E
T
E
E
I
Q
K
P
Q
Site 59
T468
K
E
W
I
Q
K
K
T
V
V
H
Q
G
D
G
Site 60
Y480
G
D
G
K
L
I
L
Y
P
N
K
N
V
Y
Q
Site 61
Y486
L
Y
P
N
K
N
V
Y
Q
I
L
F
P
D
G
Site 62
T494
Q
I
L
F
P
D
G
T
G
Q
I
H
Y
P
S
Site 63
Y499
D
G
T
G
Q
I
H
Y
P
S
G
N
L
A
M
Site 64
Y510
N
L
A
M
L
I
L
Y
A
K
M
K
K
F
T
Site 65
S524
T
Y
I
I
L
E
D
S
L
E
G
R
I
R
A
Site 66
T540
I
N
N
S
G
N
A
T
F
Y
D
E
N
S
D
Site 67
Y542
N
S
G
N
A
T
F
Y
D
E
N
S
D
I
W
Site 68
Y558
N
L
S
S
N
L
G
Y
Y
F
P
K
D
K
R
Site 69
Y559
L
S
S
N
L
G
Y
Y
F
P
K
D
K
R
Q
Site 70
Y593
I
S
L
K
I
N
E
Y
I
Q
V
Q
I
R
S
Site 71
T667
R
L
L
N
Y
A
T
T
P
D
L
E
N
F
I
Site 72
Y686
I
S
L
M
D
N
K
Y
L
K
K
M
L
S
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation