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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZKSCAN2
Full Name:
Zinc finger protein with KRAB and SCAN domains 2
Alias:
Zinc finger protein 694
Type:
Transcription factor
Mass (Da):
110910
Number AA:
967
UniProt ID:
Q63HK3
International Prot ID:
IPI00334638
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S38
S
E
P
I
L
E
G
S
D
S
S
E
T
F
R
Site 2
S40
P
I
L
E
G
S
D
S
S
E
T
F
R
K
C
Site 3
S41
I
L
E
G
S
D
S
S
E
T
F
R
K
C
F
Site 4
T43
E
G
S
D
S
S
E
T
F
R
K
C
F
R
Q
Site 5
Y53
K
C
F
R
Q
F
C
Y
E
D
V
T
G
P
H
Site 6
T57
Q
F
C
Y
E
D
V
T
G
P
H
E
A
F
S
Site 7
S112
A
Q
K
Q
C
P
Q
S
G
E
E
A
V
A
L
Site 8
S135
G
R
L
R
Q
Q
V
S
S
P
V
H
R
E
K
Site 9
S136
R
L
R
Q
Q
V
S
S
P
V
H
R
E
K
H
Site 10
S144
P
V
H
R
E
K
H
S
P
L
G
A
A
W
E
Site 11
T162
F
Q
P
E
Q
V
E
T
Q
P
R
A
V
S
R
Site 12
S168
E
T
Q
P
R
A
V
S
R
E
E
P
G
S
L
Site 13
S174
V
S
R
E
E
P
G
S
L
H
S
G
H
Q
E
Site 14
S199
L
P
K
N
A
R
P
S
P
W
V
P
A
L
A
Site 15
T217
N
T
L
D
Q
E
V
T
T
T
R
L
P
A
G
Site 16
T219
L
D
Q
E
V
T
T
T
R
L
P
A
G
S
Q
Site 17
S225
T
T
R
L
P
A
G
S
Q
E
P
V
K
D
V
Site 18
S239
V
H
V
A
R
G
F
S
Y
R
K
S
V
H
Q
Site 19
S243
R
G
F
S
Y
R
K
S
V
H
Q
I
P
A
Q
Site 20
Y254
I
P
A
Q
R
D
L
Y
R
D
F
R
K
E
N
Site 21
S270
G
N
V
V
S
L
G
S
A
V
S
T
S
N
K
Site 22
S273
V
S
L
G
S
A
V
S
T
S
N
K
I
T
R
Site 23
T274
S
L
G
S
A
V
S
T
S
N
K
I
T
R
L
Site 24
S275
L
G
S
A
V
S
T
S
N
K
I
T
R
L
E
Site 25
T289
E
Q
R
K
E
P
W
T
L
G
L
H
S
S
N
Site 26
S294
P
W
T
L
G
L
H
S
S
N
K
R
S
I
L
Site 27
S295
W
T
L
G
L
H
S
S
N
K
R
S
I
L
R
Site 28
S299
L
H
S
S
N
K
R
S
I
L
R
S
N
Y
V
Site 29
S303
N
K
R
S
I
L
R
S
N
Y
V
K
E
K
S
Site 30
Y305
R
S
I
L
R
S
N
Y
V
K
E
K
S
V
H
Site 31
S310
S
N
Y
V
K
E
K
S
V
H
A
I
Q
V
P
Site 32
T324
P
A
R
S
A
G
K
T
W
R
E
Q
Q
Q
W
Site 33
Y345
I
A
G
V
H
W
S
Y
E
E
T
K
T
F
L
Site 34
T350
W
S
Y
E
E
T
K
T
F
L
A
I
L
K
E
Site 35
Y361
I
L
K
E
S
R
F
Y
E
T
L
Q
A
C
P
Site 36
S371
L
Q
A
C
P
R
N
S
Q
V
Y
G
A
V
A
Site 37
Y374
C
P
R
N
S
Q
V
Y
G
A
V
A
E
W
L
Site 38
T389
R
E
C
G
F
L
R
T
P
E
Q
C
R
T
K
Site 39
T395
R
T
P
E
Q
C
R
T
K
F
K
S
L
Q
K
Site 40
S399
Q
C
R
T
K
F
K
S
L
Q
K
S
Y
R
K
Site 41
S403
K
F
K
S
L
Q
K
S
Y
R
K
V
R
N
G
Site 42
S434
N
P
A
A
R
A
P
S
T
D
K
P
K
E
M
Site 43
T435
P
A
A
R
A
P
S
T
D
K
P
K
E
M
I
Site 44
S459
I
S
A
K
E
H
I
S
L
V
E
E
E
E
A
Site 45
S470
E
E
E
A
A
E
D
S
D
D
D
E
I
G
I
Site 46
S483
G
I
E
F
I
R
K
S
E
I
H
G
A
P
V
Site 47
Y502
L
S
G
V
H
W
G
Y
E
E
T
K
T
F
L
Site 48
T507
W
G
Y
E
E
T
K
T
F
L
D
I
L
R
E
Site 49
T515
F
L
D
I
L
R
E
T
R
F
Y
E
A
L
Q
Site 50
Y518
I
L
R
E
T
R
F
Y
E
A
L
Q
A
C
H
Site 51
S528
L
Q
A
C
H
R
K
S
K
L
Y
G
A
V
A
Site 52
Y531
C
H
R
K
S
K
L
Y
G
A
V
A
E
Q
L
Site 53
S560
K
F
K
S
L
Q
K
S
Y
R
K
V
K
N
G
Site 54
S585
E
M
D
A
L
I
N
S
R
A
S
A
P
S
P
Site 55
S588
A
L
I
N
S
R
A
S
A
P
S
P
S
T
P
Site 56
S591
N
S
R
A
S
A
P
S
P
S
T
P
E
E
V
Site 57
S593
R
A
S
A
P
S
P
S
T
P
E
E
V
P
S
Site 58
T594
A
S
A
P
S
P
S
T
P
E
E
V
P
S
P
Site 59
S600
S
T
P
E
E
V
P
S
P
S
R
Q
E
R
G
Site 60
S602
P
E
E
V
P
S
P
S
R
Q
E
R
G
G
I
Site 61
T624
T
G
W
E
P
E
E
T
S
Q
E
A
V
I
E
Site 62
S633
Q
E
A
V
I
E
D
S
C
S
E
R
M
S
E
Site 63
S635
A
V
I
E
D
S
C
S
E
R
M
S
E
E
E
Site 64
S639
D
S
C
S
E
R
M
S
E
E
E
I
V
Q
E
Site 65
S658
G
P
P
G
L
L
Q
S
P
N
D
F
E
I
G
Site 66
T673
S
G
I
K
E
D
P
T
Q
I
V
Y
K
D
M
Site 67
Y677
E
D
P
T
Q
I
V
Y
K
D
M
E
Q
H
R
Site 68
S690
H
R
A
L
I
E
K
S
K
R
V
V
S
Q
S
Site 69
S695
E
K
S
K
R
V
V
S
Q
S
T
D
P
S
K
Site 70
S697
S
K
R
V
V
S
Q
S
T
D
P
S
K
Y
R
Site 71
S701
V
S
Q
S
T
D
P
S
K
Y
R
K
R
E
C
Site 72
Y703
Q
S
T
D
P
S
K
Y
R
K
R
E
C
I
S
Site 73
S727
I
R
Q
G
K
P
M
S
Q
P
R
D
L
G
K
Site 74
Y748
P
F
V
G
K
R
P
Y
R
L
L
K
Y
G
E
Site 75
Y753
R
P
Y
R
L
L
K
Y
G
E
S
F
G
R
S
Site 76
S756
R
L
L
K
Y
G
E
S
F
G
R
S
T
R
L
Site 77
T761
G
E
S
F
G
R
S
T
R
L
M
C
R
M
T
Site 78
Y775
T
H
H
K
E
N
P
Y
K
C
G
V
C
G
K
Site 79
S789
K
C
F
G
R
S
R
S
L
I
R
H
Q
R
I
Site 80
T798
I
R
H
Q
R
I
H
T
G
E
K
P
F
K
C
Site 81
S811
K
C
L
D
C
G
K
S
F
N
D
S
S
N
F
Site 82
S815
C
G
K
S
F
N
D
S
S
N
F
G
A
H
Q
Site 83
S816
G
K
S
F
N
D
S
S
N
F
G
A
H
Q
R
Site 84
T826
G
A
H
Q
R
I
H
T
G
E
K
P
Y
R
C
Site 85
Y831
I
H
T
G
E
K
P
Y
R
C
G
E
C
G
K
Site 86
S843
C
G
K
C
F
S
Q
S
S
S
L
I
I
H
Q
Site 87
S845
K
C
F
S
Q
S
S
S
L
I
I
H
Q
R
T
Site 88
T852
S
L
I
I
H
Q
R
T
H
T
G
E
K
P
Y
Site 89
T854
I
I
H
Q
R
T
H
T
G
E
K
P
Y
Q
C
Site 90
Y859
T
H
T
G
E
K
P
Y
Q
C
G
E
C
G
K
Site 91
T869
G
E
C
G
K
S
F
T
N
S
S
H
F
S
A
Site 92
S871
C
G
K
S
F
T
N
S
S
H
F
S
A
H
R
Site 93
S872
G
K
S
F
T
N
S
S
H
F
S
A
H
R
R
Site 94
S875
F
T
N
S
S
H
F
S
A
H
R
R
V
H
T
Site 95
T882
S
A
H
R
R
V
H
T
G
E
N
P
Y
K
C
Site 96
Y887
V
H
T
G
E
N
P
Y
K
C
V
D
C
E
K
Site 97
T910
R
E
H
R
R
I
H
T
G
E
K
P
Y
G
C
Site 98
S925
A
Q
C
G
K
R
F
S
K
S
S
V
L
T
K
Site 99
S927
C
G
K
R
F
S
K
S
S
V
L
T
K
H
R
Site 100
S928
G
K
R
F
S
K
S
S
V
L
T
K
H
R
E
Site 101
T931
F
S
K
S
S
V
L
T
K
H
R
E
V
H
V
Site 102
S948
K
P
L
P
H
P
P
S
L
Y
C
P
E
N
P
Site 103
Y950
L
P
H
P
P
S
L
Y
C
P
E
N
P
H
K
Site 104
T960
E
N
P
H
K
G
K
T
D
E
F
R
K
T
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation