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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM154B
Full Name:
Protein FAM154B
Alias:
Type:
Mass (Da):
45933
Number AA:
398
UniProt ID:
Q658L1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y24
C
G
S
D
Y
C
P
Y
E
I
V
K
Q
P
R
Site 2
Y37
P
R
H
V
P
E
E
Y
K
P
K
Q
G
K
I
Site 3
T48
Q
G
K
I
D
L
G
T
T
Y
K
R
D
L
N
Site 4
Y50
K
I
D
L
G
T
T
Y
K
R
D
L
N
S
Y
Site 5
S56
T
Y
K
R
D
L
N
S
Y
K
V
Q
P
V
A
Site 6
Y57
Y
K
R
D
L
N
S
Y
K
V
Q
P
V
A
I
Site 7
T79
V
K
K
G
K
L
D
T
V
P
T
Y
K
D
D
Site 8
T82
G
K
L
D
T
V
P
T
Y
K
D
D
Y
R
A
Site 9
Y83
K
L
D
T
V
P
T
Y
K
D
D
Y
R
A
W
Site 10
Y87
V
P
T
Y
K
D
D
Y
R
A
W
D
L
H
K
Site 11
S95
R
A
W
D
L
H
K
S
E
L
Y
K
P
E
Q
Site 12
Y104
L
Y
K
P
E
Q
T
Y
H
P
P
T
V
K
F
Site 13
T108
E
Q
T
Y
H
P
P
T
V
K
F
G
N
S
T
Site 14
T116
V
K
F
G
N
S
T
T
F
Q
D
D
F
V
P
Site 15
S131
Q
E
I
K
P
R
Q
S
F
K
P
S
S
V
V
Site 16
S135
P
R
Q
S
F
K
P
S
S
V
V
K
R
S
T
Site 17
S136
R
Q
S
F
K
P
S
S
V
V
K
R
S
T
A
Site 18
S141
P
S
S
V
V
K
R
S
T
A
P
F
N
G
I
Site 19
T142
S
S
V
V
K
R
S
T
A
P
F
N
G
I
T
Site 20
S150
A
P
F
N
G
I
T
S
H
R
L
D
Y
I
P
Site 21
Y155
I
T
S
H
R
L
D
Y
I
P
H
Q
L
E
L
Site 22
Y171
F
E
R
P
K
E
V
Y
K
P
T
D
Q
R
F
Site 23
T183
Q
R
F
E
D
L
T
T
H
R
C
D
F
Q
G
Site 24
T207
R
P
V
H
T
R
V
T
Q
N
A
L
F
E
G
Site 25
T216
N
A
L
F
E
G
S
T
E
F
R
E
S
F
Q
Site 26
S221
G
S
T
E
F
R
E
S
F
Q
P
W
E
I
P
Site 27
Y238
E
V
K
K
V
P
E
Y
V
P
P
T
G
S
M
Site 28
T242
V
P
E
Y
V
P
P
T
G
S
M
L
L
N
S
Site 29
S249
T
G
S
M
L
L
N
S
T
S
H
L
D
Y
V
Site 30
S251
S
M
L
L
N
S
T
S
H
L
D
Y
V
P
Y
Site 31
Y255
N
S
T
S
H
L
D
Y
V
P
Y
Q
A
N
H
Site 32
Y258
S
H
L
D
Y
V
P
Y
Q
A
N
H
V
V
P
Site 33
S270
V
V
P
I
R
P
V
S
Q
K
R
S
N
N
F
Site 34
S274
R
P
V
S
Q
K
R
S
N
N
F
P
F
Q
G
Site 35
S317
S
G
K
F
D
G
L
S
T
F
R
S
H
Y
V
Site 36
T318
G
K
F
D
G
L
S
T
F
R
S
H
Y
V
P
Site 37
S321
D
G
L
S
T
F
R
S
H
Y
V
P
H
E
L
Site 38
Y323
L
S
T
F
R
S
H
Y
V
P
H
E
L
I
P
Site 39
T331
V
P
H
E
L
I
P
T
E
S
C
K
P
L
N
Site 40
S333
H
E
L
I
P
T
E
S
C
K
P
L
N
I
A
Site 41
T351
S
V
P
F
D
D
V
T
M
Y
S
V
E
Y
T
Site 42
Y353
P
F
D
D
V
T
M
Y
S
V
E
Y
T
P
K
Site 43
S354
F
D
D
V
T
M
Y
S
V
E
Y
T
P
K
R
Site 44
Y357
V
T
M
Y
S
V
E
Y
T
P
K
R
Q
E
I
Site 45
T358
T
M
Y
S
V
E
Y
T
P
K
R
Q
E
I
C
Site 46
S368
R
Q
E
I
C
P
A
S
Y
P
S
P
P
G
Y
Site 47
Y369
Q
E
I
C
P
A
S
Y
P
S
P
P
G
Y
I
Site 48
S371
I
C
P
A
S
Y
P
S
P
P
G
Y
I
F
D
Site 49
Y375
S
Y
P
S
P
P
G
Y
I
F
D
N
T
N
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation