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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NARG2
Full Name:
NMDA receptor-regulated protein 2
Alias:
BRCC1
Type:
Nucleus protein
Mass (Da):
110011
Number AA:
982
UniProt ID:
Q659A1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
S
K
M
V
I
S
E
P
G
L
N
W
D
Site 2
S17
P
G
L
N
W
D
I
S
P
K
N
G
L
K
T
Site 3
T24
S
P
K
N
G
L
K
T
F
F
S
R
E
N
Y
Site 4
S27
N
G
L
K
T
F
F
S
R
E
N
Y
K
D
H
Site 5
Y31
T
F
F
S
R
E
N
Y
K
D
H
S
M
A
P
Site 6
S35
R
E
N
Y
K
D
H
S
M
A
P
S
L
K
E
Site 7
S39
K
D
H
S
M
A
P
S
L
K
E
L
R
V
L
Site 8
S47
L
K
E
L
R
V
L
S
N
R
R
I
G
E
N
Site 9
S58
I
G
E
N
L
N
A
S
A
S
S
V
E
N
E
Site 10
S60
E
N
L
N
A
S
A
S
S
V
E
N
E
P
A
Site 11
Y94
L
P
K
P
R
V
P
Y
P
R
F
S
R
F
S
Site 12
S98
R
V
P
Y
P
R
F
S
R
F
S
Q
R
E
Q
Site 13
S101
Y
P
R
F
S
R
F
S
Q
R
E
Q
R
S
Y
Site 14
S107
F
S
Q
R
E
Q
R
S
Y
V
D
L
L
V
K
Site 15
Y108
S
Q
R
E
Q
R
S
Y
V
D
L
L
V
K
Y
Site 16
Y115
Y
V
D
L
L
V
K
Y
A
K
I
P
A
N
S
Site 17
Y132
V
G
I
N
K
N
D
Y
L
Q
Y
L
D
M
K
Site 18
Y135
N
K
N
D
Y
L
Q
Y
L
D
M
K
K
H
V
Site 19
Y164
A
K
K
C
A
Q
D
Y
N
M
L
S
D
D
A
Site 20
S168
A
Q
D
Y
N
M
L
S
D
D
A
R
L
F
T
Site 21
T175
S
D
D
A
R
L
F
T
E
K
I
L
R
A
C
Site 22
Y189
C
I
E
Q
V
K
K
Y
S
E
F
Y
T
L
H
Site 23
T194
K
K
Y
S
E
F
Y
T
L
H
E
V
T
S
L
Site 24
T248
L
S
K
D
D
I
A
T
I
E
T
S
E
Q
T
Site 25
Y261
Q
T
A
E
A
M
H
Y
D
I
S
K
D
P
N
Site 26
S264
E
A
M
H
Y
D
I
S
K
D
P
N
A
E
K
Site 27
Y298
L
N
N
H
G
P
T
Y
K
E
Q
W
E
I
P
Site 28
Y323
S
K
P
V
K
V
I
Y
I
N
S
P
L
P
Q
Site 29
S326
V
K
V
I
Y
I
N
S
P
L
P
Q
K
K
M
Site 30
T334
P
L
P
Q
K
K
M
T
M
R
E
R
N
Q
I
Site 31
S360
K
N
T
S
V
P
V
S
A
V
F
M
D
K
P
Site 32
S372
D
K
P
E
E
F
I
S
E
M
D
M
S
C
E
Site 33
S388
N
E
C
R
K
I
E
S
L
E
N
L
Y
L
D
Site 34
T401
L
D
F
D
D
D
V
T
E
L
E
T
F
G
V
Site 35
T405
D
D
V
T
E
L
E
T
F
G
V
T
T
T
K
Site 36
T411
E
T
F
G
V
T
T
T
K
V
S
K
S
P
S
Site 37
S414
G
V
T
T
T
K
V
S
K
S
P
S
P
A
S
Site 38
S416
T
T
T
K
V
S
K
S
P
S
P
A
S
T
S
Site 39
S418
T
K
V
S
K
S
P
S
P
A
S
T
S
T
V
Site 40
S421
S
K
S
P
S
P
A
S
T
S
T
V
P
N
M
Site 41
T422
K
S
P
S
P
A
S
T
S
T
V
P
N
M
T
Site 42
S423
S
P
S
P
A
S
T
S
T
V
P
N
M
T
D
Site 43
T424
P
S
P
A
S
T
S
T
V
P
N
M
T
D
A
Site 44
T429
T
S
T
V
P
N
M
T
D
A
P
T
A
P
K
Site 45
T433
P
N
M
T
D
A
P
T
A
P
K
A
G
T
T
Site 46
T441
A
P
K
A
G
T
T
T
V
A
P
S
A
P
D
Site 47
S445
G
T
T
T
V
A
P
S
A
P
D
I
S
A
N
Site 48
S450
A
P
S
A
P
D
I
S
A
N
S
R
S
L
S
Site 49
S453
A
P
D
I
S
A
N
S
R
S
L
S
Q
I
L
Site 50
S455
D
I
S
A
N
S
R
S
L
S
Q
I
L
M
E
Site 51
S457
S
A
N
S
R
S
L
S
Q
I
L
M
E
Q
L
Site 52
S491
K
D
D
Q
G
F
E
S
C
E
K
V
S
N
S
Site 53
S496
F
E
S
C
E
K
V
S
N
S
D
K
P
L
I
Site 54
S498
S
C
E
K
V
S
N
S
D
K
P
L
I
Q
D
Site 55
S506
D
K
P
L
I
Q
D
S
D
L
K
T
S
D
A
Site 56
T510
I
Q
D
S
D
L
K
T
S
D
A
L
Q
L
E
Site 57
S511
Q
D
S
D
L
K
T
S
D
A
L
Q
L
E
N
Site 58
S519
D
A
L
Q
L
E
N
S
Q
E
I
E
T
S
N
Site 59
T531
T
S
N
K
N
D
M
T
I
D
I
L
H
A
D
Site 60
S551
V
L
E
N
L
D
N
S
K
E
K
T
V
G
S
Site 61
T555
L
D
N
S
K
E
K
T
V
G
S
E
A
A
K
Site 62
S558
S
K
E
K
T
V
G
S
E
A
A
K
T
E
D
Site 63
T563
V
G
S
E
A
A
K
T
E
D
T
V
L
C
S
Site 64
T566
E
A
A
K
T
E
D
T
V
L
C
S
S
D
T
Site 65
S571
E
D
T
V
L
C
S
S
D
T
D
E
E
C
L
Site 66
T573
T
V
L
C
S
S
D
T
D
E
E
C
L
I
I
Site 67
T582
E
E
C
L
I
I
D
T
E
C
K
N
N
S
D
Site 68
T592
K
N
N
S
D
G
K
T
A
V
V
G
S
N
L
Site 69
S600
A
V
V
G
S
N
L
S
S
R
P
A
S
P
N
Site 70
S601
V
V
G
S
N
L
S
S
R
P
A
S
P
N
S
Site 71
S605
N
L
S
S
R
P
A
S
P
N
S
S
S
G
Q
Site 72
S608
S
R
P
A
S
P
N
S
S
S
G
Q
A
S
V
Site 73
S609
R
P
A
S
P
N
S
S
S
G
Q
A
S
V
G
Site 74
S610
P
A
S
P
N
S
S
S
G
Q
A
S
V
G
N
Site 75
S614
N
S
S
S
G
Q
A
S
V
G
N
Q
T
N
T
Site 76
T621
S
V
G
N
Q
T
N
T
A
C
S
P
E
E
S
Site 77
S624
N
Q
T
N
T
A
C
S
P
E
E
S
C
V
L
Site 78
S628
T
A
C
S
P
E
E
S
C
V
L
K
K
P
I
Site 79
Y639
K
K
P
I
K
R
V
Y
K
K
F
D
P
V
G
Site 80
S660
D
E
L
L
K
P
I
S
R
K
V
P
E
L
P
Site 81
S674
P
L
M
N
L
E
N
S
K
Q
P
S
V
S
E
Site 82
S678
L
E
N
S
K
Q
P
S
V
S
E
Q
L
S
G
Site 83
S680
N
S
K
Q
P
S
V
S
E
Q
L
S
G
P
S
Site 84
S684
P
S
V
S
E
Q
L
S
G
P
S
D
S
S
S
Site 85
S687
S
E
Q
L
S
G
P
S
D
S
S
S
W
P
K
Site 86
S689
Q
L
S
G
P
S
D
S
S
S
W
P
K
S
G
Site 87
S690
L
S
G
P
S
D
S
S
S
W
P
K
S
G
W
Site 88
S691
S
G
P
S
D
S
S
S
W
P
K
S
G
W
P
Site 89
S695
D
S
S
S
W
P
K
S
G
W
P
S
A
F
Q
Site 90
S699
W
P
K
S
G
W
P
S
A
F
Q
K
P
K
G
Site 91
Y710
K
P
K
G
R
L
P
Y
E
L
Q
D
Y
V
E
Site 92
Y715
L
P
Y
E
L
Q
D
Y
V
E
D
T
S
E
Y
Site 93
S720
Q
D
Y
V
E
D
T
S
E
Y
L
A
P
Q
E
Site 94
Y722
Y
V
E
D
T
S
E
Y
L
A
P
Q
E
G
N
Site 95
Y732
P
Q
E
G
N
F
V
Y
K
L
F
S
L
Q
D
Site 96
T753
C
S
V
Q
R
I
E
T
R
P
R
S
K
K
R
Site 97
S757
R
I
E
T
R
P
R
S
K
K
R
K
K
I
R
Site 98
Y770
I
R
R
Q
F
P
V
Y
V
L
P
K
V
E
Y
Site 99
Y777
Y
V
L
P
K
V
E
Y
Q
A
C
Y
G
V
E
Site 100
T796
S
E
L
C
R
L
W
T
E
S
L
L
H
S
N
Site 101
S798
L
C
R
L
W
T
E
S
L
L
H
S
N
S
S
Site 102
S802
W
T
E
S
L
L
H
S
N
S
S
F
Y
V
G
Site 103
S804
E
S
L
L
H
S
N
S
S
F
Y
V
G
H
I
Site 104
S805
S
L
L
H
S
N
S
S
F
Y
V
G
H
I
D
Site 105
Y807
L
H
S
N
S
S
F
Y
V
G
H
I
D
A
F
Site 106
S826
F
L
L
E
E
I
T
S
E
E
L
K
E
K
L
Site 107
S834
E
E
L
K
E
K
L
S
A
L
K
I
S
N
L
Site 108
S854
H
I
L
K
K
L
S
S
L
Q
E
G
S
Y
L
Site 109
S859
L
S
S
L
Q
E
G
S
Y
L
L
S
H
A
A
Site 110
Y860
S
S
L
Q
E
G
S
Y
L
L
S
H
A
A
E
Site 111
S863
Q
E
G
S
Y
L
L
S
H
A
A
E
D
S
S
Site 112
S870
S
H
A
A
E
D
S
S
L
L
I
Y
K
A
S
Site 113
Y874
E
D
S
S
L
L
I
Y
K
A
S
D
G
K
V
Site 114
S877
S
L
L
I
Y
K
A
S
D
G
K
V
T
R
T
Site 115
Y886
G
K
V
T
R
T
A
Y
N
L
Y
K
T
H
C
Site 116
Y889
T
R
T
A
Y
N
L
Y
K
T
H
C
G
L
P
Site 117
T891
T
A
Y
N
L
Y
K
T
H
C
G
L
P
G
V
Site 118
Y917
D
P
S
L
L
L
P
Y
H
I
H
H
G
R
I
Site 119
T927
H
H
G
R
I
P
C
T
F
P
P
K
S
L
D
Site 120
S932
P
C
T
F
P
P
K
S
L
D
T
T
T
Q
Q
Site 121
T936
P
P
K
S
L
D
T
T
T
Q
Q
K
I
G
G
Site 122
T937
P
K
S
L
D
T
T
T
Q
Q
K
I
G
G
T
Site 123
T944
T
Q
Q
K
I
G
G
T
R
M
P
T
R
S
H
Site 124
T948
I
G
G
T
R
M
P
T
R
S
H
R
N
P
V
Site 125
S950
G
T
R
M
P
T
R
S
H
R
N
P
V
S
M
Site 126
S956
R
S
H
R
N
P
V
S
M
E
T
K
S
S
C
Site 127
S961
P
V
S
M
E
T
K
S
S
C
L
P
A
Q
Q
Site 128
S962
V
S
M
E
T
K
S
S
C
L
P
A
Q
Q
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation