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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LARP2
Full Name:
La-related protein 1B
Alias:
DKFZp434K245; DKFZp686E0316; FLJ10378; La ribonucleoprotein domain family 2; La ribonucleoprotein domain family, member 1B
Type:
Uncharacterized protein. LARP family.
Mass (Da):
105322
Number AA:
914
UniProt ID:
Q659C4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
T
P
S
E
L
V
N
T
G
F
Q
S
V
L
S
Site 2
S17
L
V
N
T
G
F
Q
S
V
L
S
Q
G
N
K
Site 3
S20
T
G
F
Q
S
V
L
S
Q
G
N
K
K
P
Q
Site 4
S40
E
E
K
V
E
K
R
S
N
S
D
S
K
E
N
Site 5
S42
K
V
E
K
R
S
N
S
D
S
K
E
N
R
E
Site 6
S44
E
K
R
S
N
S
D
S
K
E
N
R
E
T
K
Site 7
T50
D
S
K
E
N
R
E
T
K
L
N
G
P
G
E
Site 8
S60
N
G
P
G
E
N
V
S
E
D
E
A
Q
S
S
Site 9
S67
S
E
D
E
A
Q
S
S
N
Q
R
K
R
A
N
Site 10
S88
L
H
L
D
V
V
R
S
E
S
Q
E
R
P
G
Site 11
S90
L
D
V
V
R
S
E
S
Q
E
R
P
G
S
R
Site 12
S96
E
S
Q
E
R
P
G
S
R
N
S
S
R
C
Q
Site 13
S99
E
R
P
G
S
R
N
S
S
R
C
Q
P
E
A
Site 14
S100
R
P
G
S
R
N
S
S
R
C
Q
P
E
A
N
Site 15
T118
H
N
N
R
R
N
D
T
R
S
W
K
R
D
R
Site 16
S120
N
R
R
N
D
T
R
S
W
K
R
D
R
E
K
Site 17
S135
R
D
D
Q
D
D
V
S
S
V
R
S
E
G
G
Site 18
S136
D
D
Q
D
D
V
S
S
V
R
S
E
G
G
N
Site 19
S139
D
D
V
S
S
V
R
S
E
G
G
N
I
R
G
Site 20
S147
E
G
G
N
I
R
G
S
F
R
G
R
G
R
G
Site 21
Y172
N
P
R
L
N
F
D
Y
S
Y
G
Y
Q
E
H
Site 22
Y174
R
L
N
F
D
Y
S
Y
G
Y
Q
E
H
G
E
Site 23
Y176
N
F
D
Y
S
Y
G
Y
Q
E
H
G
E
R
T
Site 24
T189
R
T
D
Q
P
F
Q
T
E
L
N
T
S
M
M
Site 25
S194
F
Q
T
E
L
N
T
S
M
M
Y
Y
Y
D
D
Site 26
Y197
E
L
N
T
S
M
M
Y
Y
Y
D
D
G
T
G
Site 27
Y198
L
N
T
S
M
M
Y
Y
Y
D
D
G
T
G
V
Site 28
Y199
N
T
S
M
M
Y
Y
Y
D
D
G
T
G
V
Q
Site 29
T203
M
Y
Y
Y
D
D
G
T
G
V
Q
V
Y
P
V
Site 30
Y226
I
K
R
Q
I
E
Y
Y
F
S
V
E
N
L
E
Site 31
S228
R
Q
I
E
Y
Y
F
S
V
E
N
L
E
R
D
Site 32
S304
I
P
G
P
P
P
R
S
V
P
P
T
D
F
S
Site 33
T308
P
P
R
S
V
P
P
T
D
F
S
Q
L
I
D
Site 34
S311
S
V
P
P
T
D
F
S
Q
L
I
D
C
P
E
Site 35
S327
V
P
G
Q
A
F
C
S
H
T
E
S
A
P
N
Site 36
T329
G
Q
A
F
C
S
H
T
E
S
A
P
N
S
P
Site 37
S331
A
F
C
S
H
T
E
S
A
P
N
S
P
R
I
Site 38
S335
H
T
E
S
A
P
N
S
P
R
I
G
S
P
L
Site 39
S340
P
N
S
P
R
I
G
S
P
L
S
P
K
K
N
Site 40
S343
P
R
I
G
S
P
L
S
P
K
K
N
S
E
T
Site 41
S348
P
L
S
P
K
K
N
S
E
T
S
I
L
Q
A
Site 42
T350
S
P
K
K
N
S
E
T
S
I
L
Q
A
M
S
Site 43
S361
Q
A
M
S
R
G
L
S
T
S
L
P
D
L
D
Site 44
S363
M
S
R
G
L
S
T
S
L
P
D
L
D
S
E
Site 45
S369
T
S
L
P
D
L
D
S
E
P
W
I
E
V
K
Site 46
S389
A
P
V
K
L
R
E
S
V
S
V
P
E
G
S
Site 47
S391
V
K
L
R
E
S
V
S
V
P
E
G
S
L
N
Site 48
S396
S
V
S
V
P
E
G
S
L
N
Q
L
C
S
S
Site 49
S402
G
S
L
N
Q
L
C
S
S
E
E
P
E
Q
E
Site 50
S403
S
L
N
Q
L
C
S
S
E
E
P
E
Q
E
E
Site 51
T427
E
Q
I
G
R
K
N
T
F
T
D
W
S
D
N
Site 52
T429
I
G
R
K
N
T
F
T
D
W
S
D
N
D
S
Site 53
S432
K
N
T
F
T
D
W
S
D
N
D
S
D
Y
E
Site 54
S436
T
D
W
S
D
N
D
S
D
Y
E
I
D
D
Q
Site 55
Y438
W
S
D
N
D
S
D
Y
E
I
D
D
Q
D
L
Site 56
T452
L
N
K
I
L
I
V
T
Q
T
P
P
Y
V
K
Site 57
T454
K
I
L
I
V
T
Q
T
P
P
Y
V
K
K
H
Site 58
Y457
I
V
T
Q
T
P
P
Y
V
K
K
H
P
G
G
Site 59
T467
K
H
P
G
G
D
R
T
G
T
H
M
S
R
A
Site 60
T469
P
G
G
D
R
T
G
T
H
M
S
R
A
K
I
Site 61
S472
D
R
T
G
T
H
M
S
R
A
K
I
T
S
E
Site 62
S478
M
S
R
A
K
I
T
S
E
L
A
K
V
I
N
Site 63
Y489
K
V
I
N
D
G
L
Y
Y
Y
E
Q
D
L
W
Site 64
Y490
V
I
N
D
G
L
Y
Y
Y
E
Q
D
L
W
M
Site 65
Y491
I
N
D
G
L
Y
Y
Y
E
Q
D
L
W
M
E
Site 66
T505
E
E
D
E
N
K
H
T
A
I
K
Q
E
V
E
Site 67
T529
K
E
Q
F
E
N
L
T
P
E
L
P
F
E
P
Site 68
S545
Q
E
V
P
V
A
P
S
Q
S
R
Q
G
G
V
Site 69
T564
H
I
P
K
K
D
L
T
D
E
L
A
Q
K
L
Site 70
S585
T
S
A
A
M
V
H
S
L
P
T
A
V
P
E
Site 71
T588
A
M
V
H
S
L
P
T
A
V
P
E
S
P
R
Site 72
S593
L
P
T
A
V
P
E
S
P
R
I
H
P
T
R
Site 73
T599
E
S
P
R
I
H
P
T
R
T
P
K
T
P
R
Site 74
T601
P
R
I
H
P
T
R
T
P
K
T
P
R
T
P
Site 75
T604
H
P
T
R
T
P
K
T
P
R
T
P
R
L
Q
Site 76
T607
R
T
P
K
T
P
R
T
P
R
L
Q
D
P
N
Site 77
T616
R
L
Q
D
P
N
K
T
P
R
F
Y
P
V
V
Site 78
Y620
P
N
K
T
P
R
F
Y
P
V
V
K
E
P
K
Site 79
S633
P
K
A
I
D
V
K
S
P
R
K
R
K
T
R
Site 80
T639
K
S
P
R
K
R
K
T
R
H
S
T
N
P
P
Site 81
S642
R
K
R
K
T
R
H
S
T
N
P
P
L
E
C
Site 82
T643
K
R
K
T
R
H
S
T
N
P
P
L
E
C
H
Site 83
S657
H
V
G
W
V
M
D
S
R
D
R
G
P
G
T
Site 84
T664
S
R
D
R
G
P
G
T
S
S
V
S
T
S
N
Site 85
S665
R
D
R
G
P
G
T
S
S
V
S
T
S
N
A
Site 86
S666
D
R
G
P
G
T
S
S
V
S
T
S
N
A
S
Site 87
S668
G
P
G
T
S
S
V
S
T
S
N
A
S
P
S
Site 88
T669
P
G
T
S
S
V
S
T
S
N
A
S
P
S
E
Site 89
S670
G
T
S
S
V
S
T
S
N
A
S
P
S
E
G
Site 90
S673
S
V
S
T
S
N
A
S
P
S
E
G
A
P
L
Site 91
S675
S
T
S
N
A
S
P
S
E
G
A
P
L
A
G
Site 92
S683
E
G
A
P
L
A
G
S
Y
G
C
T
P
H
S
Site 93
T687
L
A
G
S
Y
G
C
T
P
H
S
F
P
K
F
Site 94
T708
L
L
K
E
N
G
F
T
Q
Q
V
Y
H
K
Y
Site 95
Y712
N
G
F
T
Q
Q
V
Y
H
K
Y
R
R
R
C
Site 96
Y715
T
Q
Q
V
Y
H
K
Y
R
R
R
C
L
S
E
Site 97
S721
K
Y
R
R
R
C
L
S
E
R
K
R
L
G
I
Site 98
S731
K
R
L
G
I
G
Q
S
Q
E
M
N
T
L
F
Site 99
Y754
D
H
F
N
K
K
M
Y
E
E
F
R
Q
L
A
Site 100
Y771
D
A
K
E
N
Y
R
Y
G
L
E
C
L
F
R
Site 101
Y780
L
E
C
L
F
R
F
Y
S
Y
G
L
E
K
K
Site 102
S781
E
C
L
F
R
F
Y
S
Y
G
L
E
K
K
F
Site 103
Y804
Q
E
E
T
K
K
D
Y
E
S
G
Q
L
Y
G
Site 104
Y810
D
Y
E
S
G
Q
L
Y
G
L
E
K
F
W
A
Site 105
Y818
G
L
E
K
F
W
A
Y
L
K
Y
S
Q
S
K
Site 106
S822
F
W
A
Y
L
K
Y
S
Q
S
K
T
Q
S
I
Site 107
S824
A
Y
L
K
Y
S
Q
S
K
T
Q
S
I
D
P
Site 108
T826
L
K
Y
S
Q
S
K
T
Q
S
I
D
P
K
L
Site 109
S828
Y
S
Q
S
K
T
Q
S
I
D
P
K
L
Q
E
Site 110
Y836
I
D
P
K
L
Q
E
Y
L
C
S
F
K
R
L
Site 111
S839
K
L
Q
E
Y
L
C
S
F
K
R
L
E
D
F
Site 112
S853
F
R
V
D
P
P
I
S
D
E
F
G
R
K
R
Site 113
S862
E
F
G
R
K
R
H
S
S
T
S
G
E
E
S
Site 114
S863
F
G
R
K
R
H
S
S
T
S
G
E
E
S
N
Site 115
S865
R
K
R
H
S
S
T
S
G
E
E
S
N
R
H
Site 116
S869
S
S
T
S
G
E
E
S
N
R
H
R
L
P
P
Site 117
S878
R
H
R
L
P
P
N
S
S
T
K
P
P
N
A
Site 118
S879
H
R
L
P
P
N
S
S
T
K
P
P
N
A
A
Site 119
T880
R
L
P
P
N
S
S
T
K
P
P
N
A
A
K
Site 120
S890
P
N
A
A
K
P
T
S
T
S
E
L
Q
V
P
Site 121
S900
E
L
Q
V
P
I
N
S
P
R
R
N
I
S
P
Site 122
S906
N
S
P
R
R
N
I
S
P
E
S
S
D
N
S
Site 123
S909
R
R
N
I
S
P
E
S
S
D
N
S
H
_
_
Site 124
S910
R
N
I
S
P
E
S
S
D
N
S
H
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation