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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LOC90379
Full Name:
DDB1- and CUL4-associated factor 15
Alias:
C19orf72; DCA15; DCAF15; DDB1 and CUL4 associated factor 15; MGC99481
Type:
Mass (Da):
66460
Number AA:
UniProt ID:
Q66K64
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
P
S
S
K
S
E
R
N
S
G
Site 2
S7
_
M
A
P
S
S
K
S
E
R
N
S
G
A
G
Site 3
S11
S
S
K
S
E
R
N
S
G
A
G
S
G
G
G
Site 4
S15
E
R
N
S
G
A
G
S
G
G
G
G
P
G
G
Site 5
S46
Q
L
E
R
V
K
I
S
G
Q
L
S
P
R
L
Site 6
S50
V
K
I
S
G
Q
L
S
P
R
L
F
R
K
L
Site 7
Y89
G
F
S
K
C
G
R
Y
V
L
S
Y
T
S
S
Site 8
S92
K
C
G
R
Y
V
L
S
Y
T
S
S
S
G
D
Site 9
Y93
C
G
R
Y
V
L
S
Y
T
S
S
S
G
D
D
Site 10
S96
Y
V
L
S
Y
T
S
S
S
G
D
D
D
F
S
Site 11
Y139
E
E
I
Y
S
D
L
Y
L
T
V
C
E
W
P
Site 12
Y181
D
E
N
H
R
D
I
Y
V
S
T
V
A
V
P
Site 13
S183
N
H
R
D
I
Y
V
S
T
V
A
V
P
P
P
Site 14
T184
H
R
D
I
Y
V
S
T
V
A
V
P
P
P
G
Site 15
Y226
H
T
K
Y
Q
V
V
Y
P
F
P
T
F
Q
P
Site 16
Y271
R
S
F
C
Q
I
L
Y
D
H
S
T
C
P
L
Site 17
T275
Q
I
L
Y
D
H
S
T
C
P
L
A
P
A
S
Site 18
S282
T
C
P
L
A
P
A
S
P
P
E
P
Q
S
P
Site 19
S288
A
S
P
P
E
P
Q
S
P
E
L
P
P
A
L
Site 20
S308
E
A
A
P
A
R
S
S
G
S
P
E
P
S
P
Site 21
S310
A
P
A
R
S
S
G
S
P
E
P
S
P
A
I
Site 22
S314
S
S
G
S
P
E
P
S
P
A
I
A
K
A
K
Site 23
S351
P
A
L
C
P
G
P
S
G
S
R
C
R
A
H
Site 24
S353
L
C
P
G
P
S
G
S
R
C
R
A
H
S
E
Site 25
S359
G
S
R
C
R
A
H
S
E
P
L
A
L
C
G
Site 26
S373
G
E
T
A
P
R
D
S
P
P
A
S
E
A
P
Site 27
S377
P
R
D
S
P
P
A
S
E
A
P
A
S
E
P
Site 28
S382
P
A
S
E
A
P
A
S
E
P
G
Y
V
N
Y
Site 29
Y386
A
P
A
S
E
P
G
Y
V
N
Y
T
K
L
Y
Site 30
Y393
Y
V
N
Y
T
K
L
Y
Y
V
L
E
S
G
E
Site 31
Y394
V
N
Y
T
K
L
Y
Y
V
L
E
S
G
E
G
Site 32
S414
E
L
E
D
D
K
I
S
L
P
F
V
V
T
D
Site 33
T434
L
R
P
M
R
E
R
T
A
V
Q
G
Q
Y
L
Site 34
Y440
R
T
A
V
Q
G
Q
Y
L
T
V
E
Q
L
T
Site 35
T512
E
G
Q
L
R
P
K
T
Y
H
T
S
L
K
V
Site 36
T537
T
V
S
V
G
D
L
T
E
V
K
G
Q
T
S
Site 37
S544
T
E
V
K
G
Q
T
S
G
S
V
W
S
S
Y
Site 38
S546
V
K
G
Q
T
S
G
S
V
W
S
S
Y
R
K
Site 39
S549
Q
T
S
G
S
V
W
S
S
Y
R
K
S
C
V
Site 40
S550
T
S
G
S
V
W
S
S
Y
R
K
S
C
V
D
Site 41
Y551
S
G
S
V
W
S
S
Y
R
K
S
C
V
D
M
Site 42
S567
M
K
W
L
V
P
E
S
S
G
R
Y
V
N
R
Site 43
S568
K
W
L
V
P
E
S
S
G
R
Y
V
N
R
M
Site 44
Y571
V
P
E
S
S
G
R
Y
V
N
R
M
T
N
E
Site 45
T576
G
R
Y
V
N
R
M
T
N
E
A
L
H
K
G
Site 46
S585
E
A
L
H
K
G
C
S
L
K
V
L
A
D
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation