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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MAP1S
Full Name:
Microtubule-associated protein 1S
Alias:
BPY2-interacting protein 1; BPY2IP1; C19orf5; DKFZp761H0722; FLJ10669; MAP 1S; MAP8; Microtubule-associated protein 8; Variable charge Y chromosome 2-interacting protein 1; VCY2-interacting protein 1; VCY2IP1; VCY2IP-1
Type:
Mass (Da):
112211
Number AA:
1059
UniProt ID:
Q66K74
International Prot ID:
IPI00296485
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0043025
GO:0005829
GO:0030425
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0051015
GO:0048487
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0007420
GO:0001578
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y32
G
S
P
G
L
L
T
Y
V
L
E
E
L
E
R
Site 2
S62
E
Q
L
K
V
F
V
S
R
H
S
A
T
F
S
Site 3
S65
K
V
F
V
S
R
H
S
A
T
F
S
S
I
V
Site 4
S69
S
R
H
S
A
T
F
S
S
I
V
K
G
Q
R
Site 5
S70
R
H
S
A
T
F
S
S
I
V
K
G
Q
R
S
Site 6
S77
S
I
V
K
G
Q
R
S
L
H
H
R
G
D
N
Site 7
T87
H
R
G
D
N
L
E
T
L
V
L
L
N
P
S
Site 8
S97
L
L
N
P
S
D
K
S
L
Y
D
E
L
R
N
Site 9
Y99
N
P
S
D
K
S
L
Y
D
E
L
R
N
L
L
Site 10
S111
N
L
L
L
D
P
A
S
H
K
L
L
V
L
A
Site 11
T132
T
G
E
L
L
L
Q
T
G
G
F
S
P
H
H
Site 12
T155
E
I
R
D
I
L
A
T
T
P
P
P
V
Q
P
Site 13
T156
I
R
D
I
L
A
T
T
P
P
P
V
Q
P
P
Site 14
S204
P
P
A
Q
L
P
N
S
E
G
L
C
E
F
L
Site 15
S217
F
L
E
Y
V
A
E
S
L
E
P
P
S
P
F
Site 16
S222
A
E
S
L
E
P
P
S
P
F
E
L
L
E
P
Site 17
S232
E
L
L
E
P
P
T
S
G
G
F
L
R
L
G
Site 18
S269
T
V
L
V
N
G
G
S
N
P
K
S
S
F
W
Site 19
S273
N
G
G
S
N
P
K
S
S
F
W
K
L
V
R
Site 20
S274
G
G
S
N
P
K
S
S
F
W
K
L
V
R
H
Site 21
S297
V
T
H
P
G
A
D
S
L
P
G
L
N
S
L
Site 22
S303
D
S
L
P
G
L
N
S
L
L
R
R
K
L
A
Site 23
S313
R
R
K
L
A
E
R
S
E
V
A
A
G
G
G
Site 24
S321
E
V
A
A
G
G
G
S
W
D
D
R
L
R
R
Site 25
T368
L
L
A
Q
L
G
I
T
P
L
P
L
S
R
G
Site 26
S373
G
I
T
P
L
P
L
S
R
G
P
V
P
A
K
Site 27
S402
M
Y
V
L
H
P
P
S
A
G
A
E
R
T
L
Site 28
T460
F
L
R
E
P
V
V
T
P
Q
D
L
E
G
P
Site 29
S472
E
G
P
G
R
A
E
S
K
E
S
V
G
S
R
Site 30
S475
G
R
A
E
S
K
E
S
V
G
S
R
D
S
S
Site 31
S478
E
S
K
E
S
V
G
S
R
D
S
S
K
R
E
Site 32
S481
E
S
V
G
S
R
D
S
S
K
R
E
G
L
L
Site 33
S482
S
V
G
S
R
D
S
S
K
R
E
G
L
L
A
Site 34
T490
K
R
E
G
L
L
A
T
H
P
R
P
G
Q
E
Site 35
T515
R
A
E
A
P
R
K
T
E
K
E
A
K
T
P
Site 36
T521
K
T
E
K
E
A
K
T
P
R
E
L
K
K
D
Site 37
S532
L
K
K
D
P
K
P
S
V
S
R
T
Q
P
R
Site 38
T536
P
K
P
S
V
S
R
T
Q
P
R
E
V
R
R
Site 39
S546
R
E
V
R
R
A
A
S
S
V
P
N
L
K
K
Site 40
S547
E
V
R
R
A
A
S
S
V
P
N
L
K
K
T
Site 41
T554
S
V
P
N
L
K
K
T
N
A
Q
A
A
P
K
Site 42
S567
P
K
P
R
K
A
P
S
T
S
H
S
G
F
P
Site 43
T568
K
P
R
K
A
P
S
T
S
H
S
G
F
P
P
Site 44
S569
P
R
K
A
P
S
T
S
H
S
G
F
P
P
V
Site 45
S571
K
A
P
S
T
S
H
S
G
F
P
P
V
A
N
Site 46
S582
P
V
A
N
G
P
R
S
P
P
S
L
R
C
G
Site 47
S585
N
G
P
R
S
P
P
S
L
R
C
G
E
A
S
Site 48
S592
S
L
R
C
G
E
A
S
P
P
S
A
A
C
G
Site 49
S595
C
G
E
A
S
P
P
S
A
A
C
G
S
P
A
Site 50
S631
L
E
L
P
L
A
A
S
S
I
P
R
P
R
T
Site 51
S632
E
L
P
L
A
A
S
S
I
P
R
P
R
T
P
Site 52
T638
S
S
I
P
R
P
R
T
P
S
P
E
S
H
R
Site 53
S640
I
P
R
P
R
T
P
S
P
E
S
H
R
S
P
Site 54
S643
P
R
T
P
S
P
E
S
H
R
S
P
A
E
G
Site 55
S646
P
S
P
E
S
H
R
S
P
A
E
G
S
E
R
Site 56
S651
H
R
S
P
A
E
G
S
E
R
L
S
L
S
P
Site 57
S655
A
E
G
S
E
R
L
S
L
S
P
L
R
G
G
Site 58
S657
G
S
E
R
L
S
L
S
P
L
R
G
G
E
A
Site 59
S669
G
E
A
G
P
D
A
S
P
T
V
T
T
P
T
Site 60
T671
A
G
P
D
A
S
P
T
V
T
T
P
T
V
T
Site 61
T673
P
D
A
S
P
T
V
T
T
P
T
V
T
T
P
Site 62
T674
D
A
S
P
T
V
T
T
P
T
V
T
T
P
S
Site 63
T676
S
P
T
V
T
T
P
T
V
T
T
P
S
L
P
Site 64
S688
S
L
P
A
E
V
G
S
P
H
S
T
E
V
D
Site 65
S691
A
E
V
G
S
P
H
S
T
E
V
D
E
S
L
Site 66
T692
E
V
G
S
P
H
S
T
E
V
D
E
S
L
S
Site 67
S697
H
S
T
E
V
D
E
S
L
S
V
S
F
E
Q
Site 68
S699
T
E
V
D
E
S
L
S
V
S
F
E
Q
V
L
Site 69
S709
F
E
Q
V
L
P
P
S
A
P
T
S
E
A
G
Site 70
S713
L
P
P
S
A
P
T
S
E
A
G
L
S
L
P
Site 71
S718
P
T
S
E
A
G
L
S
L
P
L
R
G
P
R
Site 72
S729
R
G
P
R
A
R
R
S
A
S
P
H
D
V
D
Site 73
S731
P
R
A
R
R
S
A
S
P
H
D
V
D
L
C
Site 74
S741
D
V
D
L
C
L
V
S
P
C
E
F
E
H
R
Site 75
S759
P
M
A
P
A
P
A
S
P
G
S
S
N
D
S
Site 76
S762
P
A
P
A
S
P
G
S
S
N
D
S
S
A
R
Site 77
S763
A
P
A
S
P
G
S
S
N
D
S
S
A
R
S
Site 78
S766
S
P
G
S
S
N
D
S
S
A
R
S
Q
E
R
Site 79
S767
P
G
S
S
N
D
S
S
A
R
S
Q
E
R
A
Site 80
S770
S
N
D
S
S
A
R
S
Q
E
R
A
G
G
L
Site 81
T782
G
G
L
G
A
E
E
T
P
P
T
S
V
S
E
Site 82
T785
G
A
E
E
T
P
P
T
S
V
S
E
S
L
P
Site 83
S786
A
E
E
T
P
P
T
S
V
S
E
S
L
P
T
Site 84
S788
E
T
P
P
T
S
V
S
E
S
L
P
T
L
S
Site 85
S790
P
P
T
S
V
S
E
S
L
P
T
L
S
D
S
Site 86
T793
S
V
S
E
S
L
P
T
L
S
D
S
D
P
V
Site 87
S795
S
E
S
L
P
T
L
S
D
S
D
P
V
P
L
Site 88
S797
S
L
P
T
L
S
D
S
D
P
V
P
L
A
P
Site 89
S809
L
A
P
G
A
A
D
S
D
E
D
T
E
G
F
Site 90
T813
A
A
D
S
D
E
D
T
E
G
F
G
V
P
R
Site 91
S838
P
P
P
L
P
D
P
S
S
I
C
M
V
D
P
Site 92
S839
P
P
L
P
D
P
S
S
I
C
M
V
D
P
E
Site 93
T852
P
E
M
L
P
P
K
T
A
R
Q
T
E
N
V
Site 94
T856
P
P
K
T
A
R
Q
T
E
N
V
S
R
T
R
Site 95
S860
A
R
Q
T
E
N
V
S
R
T
R
K
P
L
A
Site 96
S871
K
P
L
A
R
P
N
S
R
A
A
A
P
K
A
Site 97
T879
R
A
A
A
P
K
A
T
P
V
A
A
A
K
T
Site 98
S896
L
A
G
G
D
R
A
S
R
P
L
S
A
R
S
Site 99
S900
D
R
A
S
R
P
L
S
A
R
S
E
P
S
E
Site 100
S903
S
R
P
L
S
A
R
S
E
P
S
E
K
G
G
Site 101
S915
K
G
G
R
A
P
L
S
R
K
S
S
T
P
K
Site 102
S918
R
A
P
L
S
R
K
S
S
T
P
K
T
A
T
Site 103
S919
A
P
L
S
R
K
S
S
T
P
K
T
A
T
R
Site 104
T920
P
L
S
R
K
S
S
T
P
K
T
A
T
R
G
Site 105
T923
R
K
S
S
T
P
K
T
A
T
R
G
P
S
G
Site 106
T925
S
S
T
P
K
T
A
T
R
G
P
S
G
S
A
Site 107
S929
K
T
A
T
R
G
P
S
G
S
A
S
S
R
P
Site 108
S931
A
T
R
G
P
S
G
S
A
S
S
R
P
G
V
Site 109
S933
R
G
P
S
G
S
A
S
S
R
P
G
V
S
A
Site 110
S934
G
P
S
G
S
A
S
S
R
P
G
V
S
A
T
Site 111
S939
A
S
S
R
P
G
V
S
A
T
P
P
K
S
P
Site 112
T941
S
R
P
G
V
S
A
T
P
P
K
S
P
V
Y
Site 113
Y948
T
P
P
K
S
P
V
Y
L
D
L
A
Y
L
P
Site 114
Y976
Q
R
V
R
A
L
C
Y
V
I
S
G
Q
D
Q
Site 115
S979
R
A
L
C
Y
V
I
S
G
Q
D
Q
R
K
E
Site 116
T1010
W
D
R
D
L
Q
V
T
L
I
P
T
F
D
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation