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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RP1-21O18.1
Full Name:
Kazrin
Alias:
Dkfzp686d08115; Flj10199; Flj32593; Flj43398; Flj43806; Hrihfb2003; Kazrin isoform a; Kazrin isoform b; Kazrin isoform c; Kazrin isoform d; Kazrin isoform e; Kazrn; Kiaa1026; Kiaa1026 protein; Mgc126686; Mgc142181; Rp1-21o18.1
Type:
Mass (Da):
86333
Number AA:
775
UniProt ID:
Q674X7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0030057
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0031424
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
R
I
D
G
A
V
Q
S
A
S
Q
E
V
T
N
Site 2
S20
D
G
A
V
Q
S
A
S
Q
E
V
T
N
L
R
Site 3
T24
Q
S
A
S
Q
E
V
T
N
L
R
A
E
L
T
Site 4
T31
T
N
L
R
A
E
L
T
A
T
N
R
R
L
A
Site 5
T33
L
R
A
E
L
T
A
T
N
R
R
L
A
E
L
Site 6
S41
N
R
R
L
A
E
L
S
G
G
G
G
P
G
P
Site 7
S55
P
G
P
G
A
A
A
S
A
S
A
A
G
D
S
Site 8
S106
L
A
K
D
L
E
E
S
Q
G
G
K
S
S
E
Site 9
S111
E
E
S
Q
G
G
K
S
S
E
V
L
S
A
T
Site 10
S112
E
S
Q
G
G
K
S
S
E
V
L
S
A
T
E
Site 11
S116
G
K
S
S
E
V
L
S
A
T
E
L
R
V
Q
Site 12
T153
K
R
L
K
G
E
K
T
D
L
V
S
Q
M
Q
Site 13
S157
G
E
K
T
D
L
V
S
Q
M
Q
Q
L
Y
A
Site 14
Y163
V
S
Q
M
Q
Q
L
Y
A
T
L
E
S
R
E
Site 15
Y180
L
R
D
F
I
R
N
Y
E
Q
H
R
K
E
S
Site 16
S187
Y
E
Q
H
R
K
E
S
E
D
A
V
K
A
L
Site 17
T220
K
E
A
T
D
H
A
T
A
L
R
S
Q
L
D
Site 18
S259
K
D
V
P
K
R
H
S
L
A
M
P
G
E
T
Site 19
T283
V
Q
A
D
L
P
L
T
A
A
I
R
Q
S
Q
Site 20
S289
L
T
A
A
I
R
Q
S
Q
Q
T
L
Y
H
S
Site 21
T292
A
I
R
Q
S
Q
Q
T
L
Y
H
S
H
P
P
Site 22
Y294
R
Q
S
Q
Q
T
L
Y
H
S
H
P
P
H
P
Site 23
S296
S
Q
Q
T
L
Y
H
S
H
P
P
H
P
A
D
Site 24
S310
D
R
Q
A
V
R
V
S
P
C
H
S
R
Q
P
Site 25
S314
V
R
V
S
P
C
H
S
R
Q
P
S
V
I
S
Site 26
S318
P
C
H
S
R
Q
P
S
V
I
S
D
A
S
A
Site 27
S321
S
R
Q
P
S
V
I
S
D
A
S
A
A
E
G
Site 28
S324
P
S
V
I
S
D
A
S
A
A
E
G
D
R
S
Site 29
S331
S
A
A
E
G
D
R
S
S
T
P
S
D
I
N
Site 30
S332
A
A
E
G
D
R
S
S
T
P
S
D
I
N
S
Site 31
T333
A
E
G
D
R
S
S
T
P
S
D
I
N
S
P
Site 32
S335
G
D
R
S
S
T
P
S
D
I
N
S
P
R
H
Site 33
S339
S
T
P
S
D
I
N
S
P
R
H
R
T
H
S
Site 34
T344
I
N
S
P
R
H
R
T
H
S
L
C
N
G
D
Site 35
S346
S
P
R
H
R
T
H
S
L
C
N
G
D
S
P
Site 36
S352
H
S
L
C
N
G
D
S
P
G
P
V
Q
K
N
Site 37
S367
L
H
N
P
I
V
Q
S
L
E
D
L
E
D
Q
Site 38
S387
K
E
K
M
G
F
G
S
I
S
R
V
F
A
R
Site 39
S389
K
M
G
F
G
S
I
S
R
V
F
A
R
G
K
Site 40
S400
A
R
G
K
Q
R
K
S
L
D
P
G
L
F
D
Site 41
S409
D
P
G
L
F
D
D
S
D
S
Q
C
S
P
T
Site 42
S411
G
L
F
D
D
S
D
S
Q
C
S
P
T
R
Q
Site 43
S414
D
D
S
D
S
Q
C
S
P
T
R
Q
S
L
S
Site 44
T416
S
D
S
Q
C
S
P
T
R
Q
S
L
S
L
S
Site 45
S419
Q
C
S
P
T
R
Q
S
L
S
L
S
E
G
E
Site 46
S421
S
P
T
R
Q
S
L
S
L
S
E
G
E
E
Q
Site 47
S423
T
R
Q
S
L
S
L
S
E
G
E
E
Q
M
D
Site 48
T440
Q
Q
V
E
L
V
R
T
T
P
M
S
H
W
K
Site 49
T441
Q
V
E
L
V
R
T
T
P
M
S
H
W
K
A
Site 50
S444
L
V
R
T
T
P
M
S
H
W
K
A
G
T
V
Site 51
T450
M
S
H
W
K
A
G
T
V
Q
A
W
L
E
V
Site 52
S480
K
S
G
K
V
L
L
S
L
S
D
E
D
L
Q
Site 53
S495
L
G
L
G
V
C
S
S
L
H
R
R
K
L
R
Site 54
Y508
L
R
L
A
I
E
D
Y
R
D
A
E
A
G
R
Site 55
S516
R
D
A
E
A
G
R
S
L
S
K
A
A
E
L
Site 56
S518
A
E
A
G
R
S
L
S
K
A
A
E
L
D
H
Site 57
S542
D
I
G
L
S
Q
Y
S
Q
A
F
Q
N
H
L
Site 58
S557
V
D
G
R
M
L
N
S
L
M
K
R
D
L
E
Site 59
T604
E
R
R
A
R
C
E
T
Q
N
I
D
P
V
V
Site 60
Y629
R
D
I
D
L
K
E
Y
A
D
N
L
T
N
S
Site 61
T634
K
E
Y
A
D
N
L
T
N
S
G
V
H
G
A
Site 62
S676
R
H
L
A
E
E
M
S
A
V
F
H
P
A
N
Site 63
T695
R
E
A
E
R
F
G
T
P
P
G
R
A
S
S
Site 64
S701
G
T
P
P
G
R
A
S
S
V
T
R
A
G
K
Site 65
S702
T
P
P
G
R
A
S
S
V
T
R
A
G
K
E
Site 66
T704
P
G
R
A
S
S
V
T
R
A
G
K
E
E
N
Site 67
S713
A
G
K
E
E
N
S
S
G
L
K
Y
K
A
G
Site 68
Y717
E
N
S
S
G
L
K
Y
K
A
G
R
L
P
L
Site 69
S732
G
K
I
G
R
G
F
S
S
K
D
P
D
F
H
Site 70
S733
K
I
G
R
G
F
S
S
K
D
P
D
F
H
D
Site 71
Y742
D
P
D
F
H
D
D
Y
G
S
L
Q
N
E
D
Site 72
S757
C
G
D
D
D
P
Q
S
R
L
E
Q
C
R
L
Site 73
S769
C
R
L
E
G
Y
N
S
L
E
V
T
N
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation