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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATG16L1
Full Name:
Autophagy-related protein 16-1
Alias:
APG16L beta; A16L1; APG16 autophagy 16-like; APG16L; APG16L beta; APG16-like 1; ATG16 autophagy related 16-like 1; ATG16L; FLJ10035; WDR30
Type:
Autophagy; Membrane protein, peripheral; Adaptor/scaffold
Mass (Da):
68265
Number AA:
607
UniProt ID:
Q676U5
International Prot ID:
IPI00432751
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005776
GO:0019898
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0000045
GO:0051260
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
P
R
W
K
R
H
I
S
E
Q
L
R
R
R
D
Site 2
S46
Y
N
K
L
L
E
K
S
D
L
H
S
V
L
A
Site 3
S50
L
E
K
S
D
L
H
S
V
L
A
Q
K
L
Q
Site 4
S70
V
P
N
R
H
E
I
S
P
G
H
D
G
T
W
Site 5
T76
I
S
P
G
H
D
G
T
W
N
D
N
Q
L
Q
Site 6
T137
K
I
A
E
C
L
Q
T
I
S
D
L
E
T
E
Site 7
T143
Q
T
I
S
D
L
E
T
E
C
L
D
L
R
T
Site 8
Y166
N
Q
T
L
K
D
E
Y
D
A
L
Q
I
T
F
Site 9
T172
E
Y
D
A
L
Q
I
T
F
T
A
L
E
G
K
Site 10
T183
L
E
G
K
L
R
K
T
T
E
E
N
Q
E
L
Site 11
T184
E
G
K
L
R
K
T
T
E
E
N
Q
E
L
V
Site 12
S213
N
A
E
N
E
K
D
S
R
R
R
Q
A
R
L
Site 13
T247
I
E
V
I
V
D
E
T
S
D
H
T
E
E
T
Site 14
S248
E
V
I
V
D
E
T
S
D
H
T
E
E
T
S
Site 15
T251
V
D
E
T
S
D
H
T
E
E
T
S
P
V
R
Site 16
T254
T
S
D
H
T
E
E
T
S
P
V
R
A
I
S
Site 17
S255
S
D
H
T
E
E
T
S
P
V
R
A
I
S
R
Site 18
S261
T
S
P
V
R
A
I
S
R
A
A
T
K
R
L
Site 19
T265
R
A
I
S
R
A
A
T
K
R
L
S
Q
P
A
Site 20
S269
R
A
A
T
K
R
L
S
Q
P
A
G
G
L
L
Site 21
S278
P
A
G
G
L
L
D
S
I
T
N
I
F
G
R
Site 22
T280
G
G
L
L
D
S
I
T
N
I
F
G
R
R
S
Site 23
S287
T
N
I
F
G
R
R
S
V
S
S
F
P
V
P
Site 24
S289
I
F
G
R
R
S
V
S
S
F
P
V
P
Q
D
Site 25
S290
F
G
R
R
S
V
S
S
F
P
V
P
Q
D
N
Site 26
T300
V
P
Q
D
N
V
D
T
H
P
G
S
G
K
E
Site 27
S304
N
V
D
T
H
P
G
S
G
K
E
V
R
V
P
Site 28
S361
E
K
C
E
F
K
G
S
L
S
G
S
N
A
G
Site 29
S363
C
E
F
K
G
S
L
S
G
S
N
A
G
I
T
Site 30
S371
G
S
N
A
G
I
T
S
I
E
F
D
S
A
G
Site 31
Y380
E
F
D
S
A
G
S
Y
L
L
A
A
S
N
D
Site 32
T394
D
F
A
S
R
I
W
T
V
D
D
Y
R
L
R
Site 33
Y398
R
I
W
T
V
D
D
Y
R
L
R
H
T
L
T
Site 34
T403
D
D
Y
R
L
R
H
T
L
T
G
H
S
G
K
Site 35
T405
Y
R
L
R
H
T
L
T
G
H
S
G
K
V
L
Site 36
S413
G
H
S
G
K
V
L
S
A
K
F
L
L
D
N
Site 37
S425
L
D
N
A
R
I
V
S
G
S
H
D
R
T
L
Site 38
S427
N
A
R
I
V
S
G
S
H
D
R
T
L
K
L
Site 39
T431
V
S
G
S
H
D
R
T
L
K
L
W
D
L
R
Site 40
S480
F
W
D
I
R
S
E
S
I
V
R
E
M
E
L
Site 41
T501
L
D
L
N
P
E
R
T
E
L
L
S
C
S
R
Site 42
S505
P
E
R
T
E
L
L
S
C
S
R
D
D
L
L
Site 43
S507
R
T
E
L
L
S
C
S
R
D
D
L
L
K
V
Site 44
T525
R
T
N
A
I
K
Q
T
F
S
A
P
G
F
K
Site 45
S527
N
A
I
K
Q
T
F
S
A
P
G
F
K
C
G
Site 46
S543
D
W
T
R
V
V
F
S
P
D
G
S
Y
V
A
Site 47
S573
G
K
V
E
K
V
L
S
K
Q
H
S
S
S
I
Site 48
S577
K
V
L
S
K
Q
H
S
S
S
I
N
A
V
A
Site 49
S579
L
S
K
Q
H
S
S
S
I
N
A
V
A
W
S
Site 50
S590
V
A
W
S
P
S
G
S
H
V
V
S
V
D
K
Site 51
S594
P
S
G
S
H
V
V
S
V
D
K
G
C
K
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation