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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STEAP4
Full Name:
Metalloreductase STEAP4
Alias:
Six-transmembrane epithelial antigen of prostate 4;SixTransMembrane protein of prostate 2;Tumor necrosis factor, alpha-induced protein 9
Type:
Mass (Da):
51981
Number AA:
459
UniProt ID:
Q687X5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
C
I
D
A
L
P
L
T
M
N
S
S
E
K
Q
Site 2
S16
L
P
L
T
M
N
S
S
E
K
Q
E
T
V
C
Site 3
T21
N
S
S
E
K
Q
E
T
V
C
I
F
G
T
G
Site 4
S33
G
T
G
D
F
G
R
S
L
G
L
K
M
L
Q
Site 5
S44
K
M
L
Q
C
G
Y
S
V
V
F
G
S
R
N
Site 6
T55
G
S
R
N
P
Q
K
T
T
L
L
P
S
G
A
Site 7
T56
S
R
N
P
Q
K
T
T
L
L
P
S
G
A
E
Site 8
S60
Q
K
T
T
L
L
P
S
G
A
E
V
L
S
Y
Site 9
S66
P
S
G
A
E
V
L
S
Y
S
E
A
A
K
K
Site 10
Y67
S
G
A
E
V
L
S
Y
S
E
A
A
K
K
S
Site 11
S68
G
A
E
V
L
S
Y
S
E
A
A
K
K
S
G
Site 12
Y86
I
A
I
H
R
E
H
Y
D
F
L
T
E
L
T
Site 13
T90
R
E
H
Y
D
F
L
T
E
L
T
E
V
L
N
Site 14
S105
G
K
I
L
V
D
I
S
N
N
L
K
I
N
Q
Site 15
Y113
N
N
L
K
I
N
Q
Y
P
E
S
N
A
E
Y
Site 16
S116
K
I
N
Q
Y
P
E
S
N
A
E
Y
L
A
H
Site 17
Y120
Y
P
E
S
N
A
E
Y
L
A
H
L
V
P
G
Site 18
Y192
A
A
K
E
I
E
K
Y
P
L
Q
L
F
P
M
Site 19
Y225
C
V
I
R
D
V
I
Y
P
Y
V
Y
E
K
K
Site 20
Y227
I
R
D
V
I
Y
P
Y
V
Y
E
K
K
D
N
Site 21
T235
V
Y
E
K
K
D
N
T
F
R
M
A
I
S
I
Site 22
T274
I
L
Q
L
Y
R
G
T
K
Y
R
R
F
P
D
Site 23
Y276
Q
L
Y
R
G
T
K
Y
R
R
F
P
D
W
L
Site 24
T325
R
W
R
L
G
N
L
T
V
T
Q
A
I
L
K
Site 25
S338
L
K
K
E
N
P
F
S
T
S
S
A
W
L
S
Site 26
T339
K
K
E
N
P
F
S
T
S
S
A
W
L
S
D
Site 27
S340
K
E
N
P
F
S
T
S
S
A
W
L
S
D
S
Site 28
S341
E
N
P
F
S
T
S
S
A
W
L
S
D
S
Y
Site 29
S384
R
E
F
R
F
V
Q
S
K
L
G
Y
L
T
L
Site 30
S408
Y
G
G
K
R
F
L
S
P
S
N
L
R
W
Y
Site 31
S410
G
K
R
F
L
S
P
S
N
L
R
W
Y
L
P
Site 32
T445
I
M
P
C
V
D
N
T
L
T
R
I
R
Q
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation