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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HMFN0672
Full Name:
GTPase SLIP-GC
Alias:
Speckled-like pattern in the germinal center
Type:
Uncharacterized protein
Mass (Da):
95131
Number AA:
810
UniProt ID:
Q68CJ6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y20
H
P
V
E
D
D
L
Y
K
E
P
T
R
K
R
Site 2
S30
P
T
R
K
R
R
K
S
D
R
D
Q
R
F
R
Site 3
S41
Q
R
F
R
A
F
P
S
M
E
Q
S
A
L
K
Site 4
S45
A
F
P
S
M
E
Q
S
A
L
K
E
Y
E
K
Site 5
S55
K
E
Y
E
K
L
E
S
R
T
R
R
V
L
S
Site 6
S62
S
R
T
R
R
V
L
S
N
T
Y
Q
K
L
I
Site 7
T64
T
R
R
V
L
S
N
T
Y
Q
K
L
I
Q
S
Site 8
S77
Q
S
V
F
L
D
D
S
I
P
N
G
V
K
Y
Site 9
S158
E
A
K
I
H
L
L
S
D
Q
E
W
R
E
E
Site 10
S180
L
H
R
T
E
E
L
S
R
E
E
A
D
A
W
Site 11
Y204
T
W
K
L
Q
M
I
Y
G
N
G
A
E
S
K
Site 12
Y213
N
G
A
E
S
K
N
Y
E
E
L
L
R
A
K
Site 13
T227
K
P
K
R
K
I
P
T
S
R
V
I
T
L
K
Site 14
S228
P
K
R
K
I
P
T
S
R
V
I
T
L
K
A
Site 15
T232
I
P
T
S
R
V
I
T
L
K
A
E
E
A
E
Site 16
Y248
L
S
I
K
L
D
P
Y
I
R
T
Q
R
R
D
Site 17
T251
K
L
D
P
Y
I
R
T
Q
R
R
D
W
D
G
Site 18
S299
P
G
T
G
D
F
N
S
K
R
D
E
M
W
K
Site 19
S325
I
S
D
I
E
R
V
S
G
G
R
A
H
E
D
Site 20
T354
R
D
V
A
L
V
V
T
K
M
D
K
L
H
L
Site 21
Y364
D
K
L
H
L
P
E
Y
L
R
E
R
K
A
G
Site 22
S377
A
G
N
Q
A
I
Q
S
Q
R
E
A
V
L
E
Site 23
Y419
L
E
A
S
D
L
V
Y
T
V
S
A
Q
E
Y
Site 24
T420
E
A
S
D
L
V
Y
T
V
S
A
Q
E
Y
W
Site 25
Y426
Y
T
V
S
A
Q
E
Y
W
Q
Q
A
L
L
T
Site 26
T437
A
L
L
T
E
E
E
T
E
I
P
K
L
R
E
Site 27
Y445
E
I
P
K
L
R
E
Y
I
R
K
S
L
L
D
Site 28
S449
L
R
E
Y
I
R
K
S
L
L
D
K
K
K
R
Site 29
T459
D
K
K
K
R
T
V
T
K
Y
V
T
E
A
F
Site 30
Y461
K
K
R
T
V
T
K
Y
V
T
E
A
F
G
L
Site 31
T478
L
T
D
S
F
N
S
T
Q
N
L
P
N
E
H
Site 32
S489
P
N
E
H
L
H
M
S
V
L
R
R
F
A
E
Site 33
T523
P
L
Q
E
G
V
R
T
A
R
T
S
Y
R
C
Site 34
S527
G
V
R
T
A
R
T
S
Y
R
C
I
L
R
A
Site 35
Y528
V
R
T
A
R
T
S
Y
R
C
I
L
R
A
C
Site 36
S539
L
R
A
C
L
V
R
S
K
G
N
Q
G
F
H
Site 37
T563
N
G
I
Y
A
S
R
T
L
A
R
I
D
L
N
Site 38
T574
I
D
L
N
E
A
L
T
Q
P
V
Y
D
Q
I
Site 39
Y578
E
A
L
T
Q
P
V
Y
D
Q
I
D
P
V
F
Site 40
S587
Q
I
D
P
V
F
G
S
I
F
R
T
G
K
P
Site 41
T591
V
F
G
S
I
F
R
T
G
K
P
T
G
S
A
Site 42
T595
I
F
R
T
G
K
P
T
G
S
A
L
M
P
H
Site 43
T615
Q
S
L
Q
E
K
M
T
E
I
G
I
R
S
G
Site 44
Y625
G
I
R
S
G
W
K
Y
D
S
C
K
K
N
F
Site 45
Y656
L
R
R
K
R
R
I
Y
E
S
L
T
A
S
V
Site 46
S658
R
K
R
R
I
Y
E
S
L
T
A
S
V
Q
S
Site 47
T660
R
R
I
Y
E
S
L
T
A
S
V
Q
S
D
L
Site 48
S738
T
M
L
A
L
A
S
S
Q
G
D
G
L
Y
K
Site 49
Y744
S
S
Q
G
D
G
L
Y
K
E
L
A
D
V
G
Site 50
S752
K
E
L
A
D
V
G
S
E
Y
K
E
M
E
K
Site 51
S763
E
M
E
K
L
H
R
S
L
R
E
V
A
E
N
Site 52
S785
Q
E
F
L
L
R
A
S
P
S
K
A
G
P
P
Site 53
S787
F
L
L
R
A
S
P
S
K
A
G
P
P
G
T
Site 54
T794
S
K
A
G
P
P
G
T
S
L
H
S
S
L
D
Site 55
S795
K
A
G
P
P
G
T
S
L
H
S
S
L
D
D
Site 56
S799
P
G
T
S
L
H
S
S
L
D
D
G
V
R
L
Site 57
Y820
K
K
R
K
R
K
K
Y
I
Y
I
H
T
H
T
Site 58
Y822
R
K
R
K
K
Y
I
Y
I
H
T
H
T
H
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation