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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARID2
Full Name:
AT-rich interactive domain-containing protein 2
Alias:
ARID domain-containing protein 2; BRG1-associated factor 200; Zinc finger protein with activation potential; Zipzap/p200
Type:
Mass (Da):
197391
Number AA:
1835
UniProt ID:
Q68CP9
International Prot ID:
IPI00470537
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006325
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S29
E
L
R
Q
F
H
H
S
R
G
S
P
F
K
K
Site 2
S32
Q
F
H
H
S
R
G
S
P
F
K
K
I
P
A
Site 3
Y51
E
L
D
L
H
G
L
Y
T
R
V
T
T
L
G
Site 4
T55
H
G
L
Y
T
R
V
T
T
L
G
G
F
A
K
Site 5
S64
L
G
G
F
A
K
V
S
E
K
N
Q
W
G
E
Site 6
S81
E
E
F
N
F
P
R
S
C
S
N
A
A
F
A
Site 7
S83
F
N
F
P
R
S
C
S
N
A
A
F
A
L
K
Site 8
Y92
A
A
F
A
L
K
Q
Y
Y
L
R
Y
L
E
K
Site 9
Y93
A
F
A
L
K
Q
Y
Y
L
R
Y
L
E
K
Y
Site 10
Y96
L
K
Q
Y
Y
L
R
Y
L
E
K
Y
E
K
V
Site 11
Y100
Y
L
R
Y
L
E
K
Y
E
K
V
H
H
F
G
Site 12
S129
L
P
I
G
A
I
P
S
S
Y
N
Y
Q
Q
H
Site 13
S130
P
I
G
A
I
P
S
S
Y
N
Y
Q
Q
H
S
Site 14
Y131
I
G
A
I
P
S
S
Y
N
Y
Q
Q
H
S
V
Site 15
Y133
A
I
P
S
S
Y
N
Y
Q
Q
H
S
V
S
D
Site 16
S137
S
Y
N
Y
Q
Q
H
S
V
S
D
Y
L
R
Q
Site 17
Y141
Q
Q
H
S
V
S
D
Y
L
R
Q
S
Y
G
L
Site 18
S145
V
S
D
Y
L
R
Q
S
Y
G
L
S
M
D
F
Site 19
Y146
S
D
Y
L
R
Q
S
Y
G
L
S
M
D
F
N
Site 20
S149
L
R
Q
S
Y
G
L
S
M
D
F
N
S
P
N
Site 21
S154
G
L
S
M
D
F
N
S
P
N
D
Y
N
K
L
Site 22
Y158
D
F
N
S
P
N
D
Y
N
K
L
V
L
S
L
Site 23
S218
D
D
T
L
G
S
F
S
T
V
F
G
E
E
W
Site 24
T219
D
T
L
G
S
F
S
T
V
F
G
E
E
W
K
Site 25
T229
G
E
E
W
K
E
K
T
D
R
D
F
V
K
F
Site 26
S251
N
E
V
R
D
L
I
S
D
R
N
K
S
H
E
Site 27
S256
L
I
S
D
R
N
K
S
H
E
G
T
S
G
E
Site 28
S326
S
A
H
S
H
F
I
S
L
R
Q
L
G
L
D
Site 29
Y394
N
G
V
L
I
C
E
Y
V
D
Q
D
S
Y
R
Site 30
Y400
E
Y
V
D
Q
D
S
Y
R
E
I
I
C
H
L
Site 31
S472
V
K
L
I
E
H
P
S
S
S
H
Q
M
L
S
Site 32
S473
K
L
I
E
H
P
S
S
S
H
Q
M
L
S
E
Site 33
S474
L
I
E
H
P
S
S
S
H
Q
M
L
S
E
I
Site 34
S479
S
S
S
H
Q
M
L
S
E
I
R
P
Q
A
I
Site 35
T491
Q
A
I
E
Q
V
Q
T
Q
T
H
V
A
S
A
Site 36
S497
Q
T
Q
T
H
V
A
S
A
P
A
S
R
A
V
Site 37
S539
F
E
V
N
P
D
C
S
V
S
R
A
E
M
Y
Site 38
Y546
S
V
S
R
A
E
M
Y
S
E
Y
L
S
T
C
Site 39
S547
V
S
R
A
E
M
Y
S
E
Y
L
S
T
C
S
Site 40
Y549
R
A
E
M
Y
S
E
Y
L
S
T
C
S
K
L
Site 41
S551
E
M
Y
S
E
Y
L
S
T
C
S
K
L
A
R
Site 42
T552
M
Y
S
E
Y
L
S
T
C
S
K
L
A
R
G
Site 43
S554
S
E
Y
L
S
T
C
S
K
L
A
R
G
G
I
Site 44
T565
R
G
G
I
L
T
S
T
G
F
Y
K
C
L
R
Site 45
S587
V
K
R
V
E
D
S
S
S
N
G
Q
A
H
I
Site 46
S588
K
R
V
E
D
S
S
S
N
G
Q
A
H
I
H
Site 47
Y611
I
P
L
P
I
Q
M
Y
Y
Q
Q
Q
P
V
S
Site 48
Y612
P
L
P
I
Q
M
Y
Y
Q
Q
Q
P
V
S
T
Site 49
S618
Y
Y
Q
Q
Q
P
V
S
T
S
V
V
R
V
D
Site 50
S620
Q
Q
Q
P
V
S
T
S
V
V
R
V
D
S
V
Site 51
S626
T
S
V
V
R
V
D
S
V
P
D
V
S
P
A
Site 52
S631
V
D
S
V
P
D
V
S
P
A
P
S
P
A
G
Site 53
S635
P
D
V
S
P
A
P
S
P
A
G
I
P
H
G
Site 54
S643
P
A
G
I
P
H
G
S
Q
T
I
G
N
H
F
Site 55
T653
I
G
N
H
F
Q
R
T
P
V
A
N
Q
S
S
Site 56
S659
R
T
P
V
A
N
Q
S
S
N
L
T
A
T
Q
Site 57
T663
A
N
Q
S
S
N
L
T
A
T
Q
M
S
F
P
Site 58
T665
Q
S
S
N
L
T
A
T
Q
M
S
F
P
V
Q
Site 59
S668
N
L
T
A
T
Q
M
S
F
P
V
Q
G
V
H
Site 60
T676
F
P
V
Q
G
V
H
T
V
A
Q
T
V
S
R
Site 61
T680
G
V
H
T
V
A
Q
T
V
S
R
I
P
Q
N
Site 62
S689
S
R
I
P
Q
N
P
S
P
H
T
H
Q
Q
Q
Site 63
T692
P
Q
N
P
S
P
H
T
H
Q
Q
Q
N
A
P
Site 64
T701
Q
Q
Q
N
A
P
V
T
V
I
Q
S
K
A
P
Site 65
S722
K
A
T
V
I
Q
N
S
I
P
Q
T
G
V
P
Site 66
S741
V
G
G
G
P
P
Q
S
S
V
V
Q
N
H
S
Site 67
S742
G
G
G
P
P
Q
S
S
V
V
Q
N
H
S
T
Site 68
S748
S
S
V
V
Q
N
H
S
T
G
P
Q
P
V
T
Site 69
T755
S
T
G
P
Q
P
V
T
V
V
N
S
Q
T
L
Site 70
S759
Q
P
V
T
V
V
N
S
Q
T
L
L
H
H
P
Site 71
S767
Q
T
L
L
H
H
P
S
V
I
P
Q
Q
S
P
Site 72
S773
P
S
V
I
P
Q
Q
S
P
L
H
T
V
V
P
Site 73
T777
P
Q
Q
S
P
L
H
T
V
V
P
G
Q
I
P
Site 74
T787
P
G
Q
I
P
S
G
T
P
V
T
V
I
Q
Q
Site 75
T814
N
I
P
A
C
T
S
T
V
S
Q
G
Q
Q
L
Site 76
S816
P
A
C
T
S
T
V
S
Q
G
Q
Q
L
I
T
Site 77
T823
S
Q
G
Q
Q
L
I
T
T
S
P
Q
P
V
Q
Site 78
S825
G
Q
Q
L
I
T
T
S
P
Q
P
V
Q
T
S
Site 79
S833
P
Q
P
V
Q
T
S
S
Q
Q
T
S
A
G
S
Site 80
T836
V
Q
T
S
S
Q
Q
T
S
A
G
S
Q
S
Q
Site 81
S837
Q
T
S
S
Q
Q
T
S
A
G
S
Q
S
Q
D
Site 82
S840
S
Q
Q
T
S
A
G
S
Q
S
Q
D
T
V
I
Site 83
S842
Q
T
S
A
G
S
Q
S
Q
D
T
V
I
I
A
Site 84
T845
A
G
S
Q
S
Q
D
T
V
I
I
A
P
P
Q
Site 85
S857
P
P
Q
Y
V
T
T
S
A
S
N
I
V
S
A
Site 86
S859
Q
Y
V
T
T
S
A
S
N
I
V
S
A
T
S
Site 87
S889
G
V
P
S
P
Q
A
S
R
V
G
F
Q
N
I
Site 88
S903
I
A
P
K
P
L
P
S
Q
Q
V
S
S
T
V
Site 89
S907
P
L
P
S
Q
Q
V
S
S
T
V
V
Q
Q
P
Site 90
T909
P
S
Q
Q
V
S
S
T
V
V
Q
Q
P
I
Q
Site 91
S925
P
Q
Q
P
T
Q
Q
S
V
V
I
V
S
Q
P
Site 92
T963
A
G
Q
T
V
Q
L
T
G
Q
P
N
I
T
P
Site 93
T969
L
T
G
Q
P
N
I
T
P
S
S
S
P
S
P
Site 94
S971
G
Q
P
N
I
T
P
S
S
S
P
S
P
V
P
Site 95
S972
Q
P
N
I
T
P
S
S
S
P
S
P
V
P
A
Site 96
S973
P
N
I
T
P
S
S
S
P
S
P
V
P
A
T
Site 97
S975
I
T
P
S
S
S
P
S
P
V
P
A
T
N
N
Site 98
T980
S
P
S
P
V
P
A
T
N
N
Q
V
P
T
A
Site 99
T986
A
T
N
N
Q
V
P
T
A
M
S
S
S
S
T
Site 100
S989
N
Q
V
P
T
A
M
S
S
S
S
T
P
Q
S
Site 101
S990
Q
V
P
T
A
M
S
S
S
S
T
P
Q
S
Q
Site 102
S991
V
P
T
A
M
S
S
S
S
T
P
Q
S
Q
G
Site 103
S992
P
T
A
M
S
S
S
S
T
P
Q
S
Q
G
P
Site 104
T993
T
A
M
S
S
S
S
T
P
Q
S
Q
G
P
P
Site 105
S996
S
S
S
S
T
P
Q
S
Q
G
P
P
P
T
V
Site 106
T1002
Q
S
Q
G
P
P
P
T
V
S
Q
M
L
S
V
Site 107
S1004
Q
G
P
P
P
T
V
S
Q
M
L
S
V
K
R
Site 108
S1008
P
T
V
S
Q
M
L
S
V
K
R
Q
Q
Q
Q
Site 109
S1018
R
Q
Q
Q
Q
Q
H
S
P
A
P
P
P
Q
Q
Site 110
S1054
A
G
V
G
Q
P
A
S
G
E
S
S
L
I
K
Site 111
S1058
Q
P
A
S
G
E
S
S
L
I
K
Q
L
L
L
Site 112
S1071
L
L
P
K
R
G
P
S
T
P
G
G
K
L
I
Site 113
T1072
L
P
K
R
G
P
S
T
P
G
G
K
L
I
L
Site 114
S1094
P
N
N
A
R
A
P
S
P
Q
V
V
Y
Q
V
Site 115
Y1099
A
P
S
P
Q
V
V
Y
Q
V
A
S
N
Q
A
Site 116
S1132
Q
N
V
Q
L
V
P
S
A
M
P
P
S
G
G
Site 117
T1142
P
P
S
G
G
V
Q
T
V
P
I
S
N
L
Q
Site 118
T1186
N
T
S
F
A
P
A
T
V
S
Q
G
N
A
T
Site 119
S1188
S
F
A
P
A
T
V
S
Q
G
N
A
T
Q
L
Site 120
T1220
P
V
Q
T
L
P
A
T
Q
A
S
P
A
G
Q
Site 121
S1223
T
L
P
A
T
Q
A
S
P
A
G
Q
S
S
C
Site 122
S1229
A
S
P
A
G
Q
S
S
C
T
T
A
T
P
P
Site 123
T1232
A
G
Q
S
S
C
T
T
A
T
P
P
F
K
G
Site 124
T1234
Q
S
S
C
T
T
A
T
P
P
F
K
G
D
K
Site 125
S1270
I
E
V
M
E
N
P
S
C
R
R
G
A
T
N
Site 126
T1276
P
S
C
R
R
G
A
T
N
T
S
N
G
D
T
Site 127
T1278
C
R
R
G
A
T
N
T
S
N
G
D
T
K
E
Site 128
S1279
R
R
G
A
T
N
T
S
N
G
D
T
K
E
N
Site 129
T1283
T
N
T
S
N
G
D
T
K
E
N
E
M
H
V
Site 130
S1292
E
N
E
M
H
V
G
S
L
L
N
G
R
K
Y
Site 131
Y1299
S
L
L
N
G
R
K
Y
S
D
S
S
L
P
P
Site 132
S1300
L
L
N
G
R
K
Y
S
D
S
S
L
P
P
S
Site 133
S1302
N
G
R
K
Y
S
D
S
S
L
P
P
S
N
S
Site 134
S1303
G
R
K
Y
S
D
S
S
L
P
P
S
N
S
G
Site 135
S1307
S
D
S
S
L
P
P
S
N
S
G
K
I
Q
S
Site 136
S1309
S
S
L
P
P
S
N
S
G
K
I
Q
S
E
T
Site 137
S1314
S
N
S
G
K
I
Q
S
E
T
N
Q
C
S
L
Site 138
T1316
S
G
K
I
Q
S
E
T
N
Q
C
S
L
I
S
Site 139
S1320
Q
S
E
T
N
Q
C
S
L
I
S
N
G
P
S
Site 140
S1323
T
N
Q
C
S
L
I
S
N
G
P
S
L
E
L
Site 141
S1327
S
L
I
S
N
G
P
S
L
E
L
G
E
N
G
Site 142
S1336
E
L
G
E
N
G
A
S
G
K
Q
N
S
E
Q
Site 143
S1341
G
A
S
G
K
Q
N
S
E
Q
I
D
M
Q
D
Site 144
S1351
I
D
M
Q
D
I
K
S
D
L
R
K
P
L
V
Site 145
S1370
D
F
D
K
G
D
G
S
H
L
S
K
N
I
P
Site 146
S1373
K
G
D
G
S
H
L
S
K
N
I
P
N
H
K
Site 147
T1381
K
N
I
P
N
H
K
T
S
N
H
V
G
N
G
Site 148
S1391
H
V
G
N
G
E
I
S
P
M
E
P
Q
G
T
Site 149
T1398
S
P
M
E
P
Q
G
T
L
D
I
T
Q
Q
D
Site 150
T1402
P
Q
G
T
L
D
I
T
Q
Q
D
T
A
K
G
Site 151
S1416
G
D
Q
L
E
R
I
S
N
G
P
V
L
T
L
Site 152
S1430
L
G
G
S
S
V
S
S
I
Q
E
A
S
N
A
Site 153
T1439
Q
E
A
S
N
A
A
T
Q
Q
F
S
G
T
D
Site 154
S1455
L
N
G
P
L
A
S
S
L
N
S
D
V
P
Q
Site 155
S1458
P
L
A
S
S
L
N
S
D
V
P
Q
Q
R
P
Site 156
S1466
D
V
P
Q
Q
R
P
S
V
V
V
S
P
H
S
Site 157
S1470
Q
R
P
S
V
V
V
S
P
H
S
T
T
S
V
Site 158
S1476
V
S
P
H
S
T
T
S
V
I
Q
G
H
Q
I
Site 159
S1489
Q
I
I
A
V
P
D
S
G
S
K
V
S
H
S
Site 160
S1491
I
A
V
P
D
S
G
S
K
V
S
H
S
P
A
Site 161
S1494
P
D
S
G
S
K
V
S
H
S
P
A
L
S
S
Site 162
S1496
S
G
S
K
V
S
H
S
P
A
L
S
S
D
V
Site 163
S1500
V
S
H
S
P
A
L
S
S
D
V
R
S
T
N
Site 164
S1501
S
H
S
P
A
L
S
S
D
V
R
S
T
N
G
Site 165
S1505
A
L
S
S
D
V
R
S
T
N
G
T
A
E
C
Site 166
T1506
L
S
S
D
V
R
S
T
N
G
T
A
E
C
K
Site 167
T1509
D
V
R
S
T
N
G
T
A
E
C
K
T
V
K
Site 168
T1514
N
G
T
A
E
C
K
T
V
K
R
P
A
E
D
Site 169
T1522
V
K
R
P
A
E
D
T
D
R
E
T
V
A
G
Site 170
T1526
A
E
D
T
D
R
E
T
V
A
G
I
P
N
K
Site 171
T1540
K
V
G
V
R
I
V
T
I
S
D
P
N
N
A
Site 172
S1550
D
P
N
N
A
G
C
S
A
T
M
V
A
V
P
Site 173
S1572
V
A
K
V
A
I
E
S
A
V
Q
Q
K
Q
Q
Site 174
Y1584
K
Q
Q
H
P
P
T
Y
V
Q
N
V
V
P
Q
Site 175
T1593
Q
N
V
V
P
Q
N
T
P
M
P
P
S
P
A
Site 176
S1598
Q
N
T
P
M
P
P
S
P
A
V
Q
V
Q
G
Site 177
S1609
Q
V
Q
G
Q
P
N
S
S
Q
P
S
P
F
S
Site 178
S1610
V
Q
G
Q
P
N
S
S
Q
P
S
P
F
S
G
Site 179
S1613
Q
P
N
S
S
Q
P
S
P
F
S
G
S
S
Q
Site 180
S1616
S
S
Q
P
S
P
F
S
G
S
S
Q
P
G
D
Site 181
S1618
Q
P
S
P
F
S
G
S
S
Q
P
G
D
P
M
Site 182
S1619
P
S
P
F
S
G
S
S
Q
P
G
D
P
M
R
Site 183
Y1651
Q
T
P
S
Q
V
F
Y
H
A
A
T
E
H
G
Site 184
Y1663
E
H
G
G
K
D
V
Y
P
G
Q
C
L
W
E
Site 185
S1681
P
F
Q
R
Q
R
F
S
F
I
T
H
L
Q
D
Site 186
T1684
R
Q
R
F
S
F
I
T
H
L
Q
D
K
H
C
Site 187
S1692
H
L
Q
D
K
H
C
S
K
D
A
L
L
A
G
Site 188
S1710
D
E
P
G
Q
A
G
S
Q
K
S
S
T
K
Q
Site 189
S1713
G
Q
A
G
S
Q
K
S
S
T
K
Q
P
T
V
Site 190
S1714
Q
A
G
S
Q
K
S
S
T
K
Q
P
T
V
G
Site 191
T1715
A
G
S
Q
K
S
S
T
K
Q
P
T
V
G
G
Site 192
T1719
K
S
S
T
K
Q
P
T
V
G
G
T
S
S
T
Site 193
T1723
K
Q
P
T
V
G
G
T
S
S
T
P
R
A
Q
Site 194
S1724
Q
P
T
V
G
G
T
S
S
T
P
R
A
Q
K
Site 195
S1725
P
T
V
G
G
T
S
S
T
P
R
A
Q
K
A
Site 196
T1726
T
V
G
G
T
S
S
T
P
R
A
Q
K
A
I
Site 197
S1748
L
M
A
L
R
R
G
S
R
N
L
V
F
R
D
Site 198
T1757
N
L
V
F
R
D
F
T
D
E
K
E
G
P
I
Site 199
T1765
D
E
K
E
G
P
I
T
K
H
I
R
L
T
A
Site 200
Y1782
I
L
K
N
I
G
K
Y
S
E
C
G
R
R
L
Site 201
S1783
L
K
N
I
G
K
Y
S
E
C
G
R
R
L
L
Site 202
S1798
K
R
H
E
N
N
L
S
V
L
A
I
S
N
M
Site 203
S1808
A
I
S
N
M
E
A
S
S
T
L
A
K
C
L
Site 204
T1810
S
N
M
E
A
S
S
T
L
A
K
C
L
Y
E
Site 205
T1821
C
L
Y
E
L
N
F
T
V
Q
S
K
E
Q
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation