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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C1orf175
Full Name:
Uncharacterized protein C1orf175
Alias:
ca175; chromosome 1 open reading frame 175; flj46354; loc374977
Type:
Mass (Da):
141510
Number AA:
UniProt ID:
Q68CQ1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T18
F
H
E
D
P
K
M
T
P
S
P
P
S
C
G
Site 2
S20
E
D
P
K
M
T
P
S
P
P
S
C
G
A
P
Site 3
S23
K
M
T
P
S
P
P
S
C
G
A
P
G
L
G
Site 4
S31
C
G
A
P
G
L
G
S
G
T
I
P
Q
P
H
Site 5
S64
L
V
P
D
L
N
D
S
L
S
P
V
S
G
E
Site 6
S66
P
D
L
N
D
S
L
S
P
V
S
G
E
A
S
Site 7
S69
N
D
S
L
S
P
V
S
G
E
A
S
G
L
V
Site 8
S73
S
P
V
S
G
E
A
S
G
L
V
S
E
N
T
Site 9
S77
G
E
A
S
G
L
V
S
E
N
T
P
R
P
D
Site 10
T80
S
G
L
V
S
E
N
T
P
R
P
D
D
S
R
Site 11
S86
N
T
P
R
P
D
D
S
R
A
I
A
P
A
S
Site 12
T97
A
P
A
S
L
Q
I
T
S
S
C
S
G
E
A
Site 13
S99
A
S
L
Q
I
T
S
S
C
S
G
E
A
L
D
Site 14
S109
G
E
A
L
D
L
D
S
K
D
V
S
R
P
D
Site 15
S113
D
L
D
S
K
D
V
S
R
P
D
S
Q
G
R
Site 16
S117
K
D
V
S
R
P
D
S
Q
G
R
L
C
P
A
Site 17
S125
Q
G
R
L
C
P
A
S
N
P
I
L
S
P
S
Site 18
S130
P
A
S
N
P
I
L
S
P
S
S
T
E
A
P
Site 19
S132
S
N
P
I
L
S
P
S
S
T
E
A
P
R
L
Site 20
S133
N
P
I
L
S
P
S
S
T
E
A
P
R
L
S
Site 21
T134
P
I
L
S
P
S
S
T
E
A
P
R
L
S
S
Site 22
S140
S
T
E
A
P
R
L
S
S
G
N
H
P
Q
S
Site 23
S141
T
E
A
P
R
L
S
S
G
N
H
P
Q
S
N
Site 24
S147
S
S
G
N
H
P
Q
S
N
S
E
D
A
F
K
Site 25
S149
G
N
H
P
Q
S
N
S
E
D
A
F
K
C
L
Site 26
S168
F
K
L
G
Q
R
N
S
N
P
S
R
H
E
L
Site 27
S171
G
Q
R
N
S
N
P
S
R
H
E
L
N
P
F
Site 28
S183
N
P
F
I
R
H
H
S
R
E
G
L
V
L
G
Site 29
S206
K
A
L
L
I
P
T
S
N
S
S
L
D
L
D
Site 30
S208
L
L
I
P
T
S
N
S
S
L
D
L
D
S
N
Site 31
S209
L
I
P
T
S
N
S
S
L
D
L
D
S
N
P
Site 32
S214
N
S
S
L
D
L
D
S
N
P
L
L
N
M
G
Site 33
S222
N
P
L
L
N
M
G
S
R
N
T
S
K
L
N
Site 34
T225
L
N
M
G
S
R
N
T
S
K
L
N
L
N
V
Site 35
S226
N
M
G
S
R
N
T
S
K
L
N
L
N
V
A
Site 36
S236
N
L
N
V
A
P
D
S
H
G
T
L
I
P
D
Site 37
T244
H
G
T
L
I
P
D
T
N
E
T
I
T
L
A
Site 38
T249
P
D
T
N
E
T
I
T
L
A
S
H
N
I
S
Site 39
S252
N
E
T
I
T
L
A
S
H
N
I
S
E
S
V
Site 40
S256
T
L
A
S
H
N
I
S
E
S
V
S
K
G
A
Site 41
S258
A
S
H
N
I
S
E
S
V
S
K
G
A
F
S
Site 42
S260
H
N
I
S
E
S
V
S
K
G
A
F
S
T
T
Site 43
S265
S
V
S
K
G
A
F
S
T
T
W
S
T
S
S
Site 44
T266
V
S
K
G
A
F
S
T
T
W
S
T
S
S
K
Site 45
T267
S
K
G
A
F
S
T
T
W
S
T
S
S
K
E
Site 46
S269
G
A
F
S
T
T
W
S
T
S
S
K
E
T
M
Site 47
S272
S
T
T
W
S
T
S
S
K
E
T
M
N
V
A
Site 48
T275
W
S
T
S
S
K
E
T
M
N
V
A
S
S
G
Site 49
S280
K
E
T
M
N
V
A
S
S
G
H
S
R
S
D
Site 50
S284
N
V
A
S
S
G
H
S
R
S
D
L
S
V
T
Site 51
S286
A
S
S
G
H
S
R
S
D
L
S
V
T
I
T
Site 52
S289
G
H
S
R
S
D
L
S
V
T
I
T
Q
A
S
Site 53
T291
S
R
S
D
L
S
V
T
I
T
Q
A
S
Y
V
Site 54
S309
P
G
S
S
Y
G
I
S
L
H
S
S
T
H
E
Site 55
S312
S
Y
G
I
S
L
H
S
S
T
H
E
P
N
S
Site 56
S313
Y
G
I
S
L
H
S
S
T
H
E
P
N
S
T
Site 57
T314
G
I
S
L
H
S
S
T
H
E
P
N
S
T
I
Site 58
S319
S
S
T
H
E
P
N
S
T
I
S
P
P
S
C
Site 59
T320
S
T
H
E
P
N
S
T
I
S
P
P
S
C
M
Site 60
S322
H
E
P
N
S
T
I
S
P
P
S
C
M
T
L
Site 61
S342
E
T
L
S
L
D
S
S
L
L
F
S
D
T
S
Site 62
T350
L
L
F
S
D
T
S
T
L
T
L
S
S
Q
Q
Site 63
T352
F
S
D
T
S
T
L
T
L
S
S
Q
Q
D
D
Site 64
S354
D
T
S
T
L
T
L
S
S
Q
Q
D
D
A
K
Site 65
S376
P
L
E
E
N
L
E
S
W
S
E
M
A
S
I
Site 66
S378
E
E
N
L
E
S
W
S
E
M
A
S
I
K
V
Site 67
S382
E
S
W
S
E
M
A
S
I
K
V
G
Q
F
P
Site 68
S395
F
P
L
G
F
P
I
S
N
P
A
G
K
D
A
Site 69
T404
P
A
G
K
D
A
V
T
L
Q
G
I
P
E
G
Site 70
T427
L
V
K
V
P
E
K
T
E
G
G
N
N
M
A
Site 71
T440
M
A
L
V
E
N
V
T
T
L
Q
K
S
Q
D
Site 72
T441
A
L
V
E
N
V
T
T
L
Q
K
S
Q
D
L
Site 73
S445
N
V
T
T
L
Q
K
S
Q
D
L
L
E
A
E
Site 74
T457
E
A
E
G
E
K
K
T
M
I
K
K
I
M
R
Site 75
S473
I
Q
E
E
P
L
D
S
L
S
S
S
V
R
K
Site 76
S475
E
E
P
L
D
S
L
S
S
S
V
R
K
Q
A
Site 77
S476
E
P
L
D
S
L
S
S
S
V
R
K
Q
A
M
Site 78
S477
P
L
D
S
L
S
S
S
V
R
K
Q
A
M
E
Site 79
S490
M
E
I
L
T
Q
L
S
H
T
Q
P
T
L
G
Site 80
T653
R
A
R
D
K
E
E
T
N
K
K
E
L
Y
E
Site 81
Y659
E
T
N
K
K
E
L
Y
E
S
N
K
H
F
L
Site 82
S661
N
K
K
E
L
Y
E
S
N
K
H
F
L
G
P
Site 83
Y669
N
K
H
F
L
G
P
Y
N
P
V
S
P
C
Q
Site 84
S673
L
G
P
Y
N
P
V
S
P
C
Q
N
I
L
R
Site 85
S709
L
E
G
L
K
G
S
S
E
A
P
G
K
D
S
Site 86
S730
A
S
E
V
M
L
S
S
V
L
E
W
Y
R
H
Site 87
Y751
P
E
I
M
Q
G
I
Y
M
Q
L
S
H
I
Q
Site 88
S755
Q
G
I
Y
M
Q
L
S
H
I
Q
E
P
R
A
Site 89
T829
S
L
K
E
K
P
V
T
K
E
G
R
A
S
I
Site 90
S853
C
E
L
L
S
V
N
S
C
M
G
R
V
R
R
Site 91
S898
T
K
K
G
A
Q
P
S
P
F
V
P
V
R
W
Site 92
Y921
L
L
R
M
G
C
S
Y
E
T
T
F
L
E
D
Site 93
T924
M
G
C
S
Y
E
T
T
F
L
E
D
Q
G
G
Site 94
S940
E
L
M
E
Q
V
E
S
H
H
R
G
V
A
L
Site 95
Y955
L
A
R
A
M
V
Q
Y
S
C
Q
E
L
C
R
Site 96
T981
G
D
E
K
H
R
I
T
A
T
A
F
F
V
E
Site 97
Y1002
V
R
R
I
P
E
E
Y
S
L
G
R
M
A
E
Site 98
S1003
R
R
I
P
E
E
Y
S
L
G
R
M
A
E
G
Site 99
S1012
G
R
M
A
E
G
L
S
H
H
D
P
I
M
K
Site 100
S1022
D
P
I
M
K
V
L
S
I
R
G
L
V
I
L
Site 101
S1033
L
V
I
L
A
R
R
S
E
K
T
A
K
V
K
Site 102
T1036
L
A
R
R
S
E
K
T
A
K
V
K
A
L
L
Site 103
S1079
R
D
Q
K
L
M
D
S
A
V
Y
V
E
M
L
Site 104
S1094
Q
I
L
L
P
H
F
S
D
A
R
E
V
V
R
Site 105
S1102
D
A
R
E
V
V
R
S
S
C
I
N
L
Y
G
Site 106
S1103
A
R
E
V
V
R
S
S
C
I
N
L
Y
G
K
Site 107
Y1108
R
S
S
C
I
N
L
Y
G
K
V
V
Q
K
L
Site 108
T1120
Q
K
L
R
A
P
R
T
Q
A
M
E
E
Q
L
Site 109
Y1169
W
E
L
P
K
R
A
Y
S
R
K
P
W
D
N
Site 110
S1170
E
L
P
K
R
A
Y
S
R
K
P
W
D
N
Q
Site 111
S1210
S
L
E
Y
A
K
N
S
R
A
S
L
R
K
C
Site 112
S1213
Y
A
K
N
S
R
A
S
L
R
K
C
S
V
M
Site 113
T1234
P
C
M
E
S
I
M
T
E
D
R
L
N
E
V
Site 114
Y1259
P
E
A
S
V
C
I
Y
A
A
Q
V
Q
D
H
Site 115
S1294
S
A
T
T
H
R
W
S
P
S
C
E
N
L
P
Site 116
S1296
T
T
H
R
W
S
P
S
C
E
N
L
P
T
S
Site 117
T1302
P
S
C
E
N
L
P
T
S
H
Q
R
R
S
W
Site 118
S1308
P
T
S
H
Q
R
R
S
W
I
M
Q
A
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation