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Updated November 2019
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Protein Info
Short Name:
SLFN13
Full Name:
Schlafen family member 13
Alias:
Type:
Mass (Da):
102045
Number AA:
897
UniProt ID:
Q68D06
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
N
H
C
S
L
G
V
Y
P
S
Y
P
D
L
V
Site 2
T37
N
R
K
K
L
Q
K
T
Q
R
D
Q
E
R
A
Site 3
T73
A
N
R
D
E
R
P
T
E
M
G
L
D
L
E
Site 4
S82
M
G
L
D
L
E
E
S
L
R
K
L
I
Q
Y
Site 5
Y91
R
K
L
I
Q
Y
P
Y
L
Q
A
F
F
E
T
Site 6
S113
Y
I
F
V
K
S
W
S
G
D
P
F
L
K
D
Site 7
S122
D
P
F
L
K
D
G
S
F
N
S
R
I
C
S
Site 8
S125
L
K
D
G
S
F
N
S
R
I
C
S
L
S
S
Site 9
S131
N
S
R
I
C
S
L
S
S
S
L
Y
C
R
S
Site 10
S132
S
R
I
C
S
L
S
S
S
L
Y
C
R
S
G
Site 11
S133
R
I
C
S
L
S
S
S
L
Y
C
R
S
G
T
Site 12
Y135
C
S
L
S
S
S
L
Y
C
R
S
G
T
S
V
Site 13
S138
S
S
S
L
Y
C
R
S
G
T
S
V
L
H
M
Site 14
T140
S
L
Y
C
R
S
G
T
S
V
L
H
M
N
S
Site 15
S141
L
Y
C
R
S
G
T
S
V
L
H
M
N
S
R
Site 16
T156
Q
A
F
D
F
L
K
T
K
E
R
Q
S
K
Y
Site 17
S161
L
K
T
K
E
R
Q
S
K
Y
N
L
I
N
E
Site 18
Y163
T
K
E
R
Q
S
K
Y
N
L
I
N
E
G
S
Site 19
S170
Y
N
L
I
N
E
G
S
P
P
S
K
I
M
K
Site 20
S173
I
N
E
G
S
P
P
S
K
I
M
K
A
V
Y
Site 21
Y180
S
K
I
M
K
A
V
Y
Q
N
I
S
E
S
N
Site 22
S186
V
Y
Q
N
I
S
E
S
N
P
A
Y
E
V
F
Site 23
Y190
I
S
E
S
N
P
A
Y
E
V
F
Q
T
D
T
Site 24
T195
P
A
Y
E
V
F
Q
T
D
T
I
E
Y
G
E
Site 25
T197
Y
E
V
F
Q
T
D
T
I
E
Y
G
E
I
L
Site 26
S205
I
E
Y
G
E
I
L
S
F
P
E
S
P
S
I
Site 27
S209
E
I
L
S
F
P
E
S
P
S
I
E
F
K
Q
Site 28
S211
L
S
F
P
E
S
P
S
I
E
F
K
Q
F
S
Site 29
Y225
S
T
K
H
I
Q
Q
Y
V
E
N
I
I
P
E
Site 30
S268
K
E
Q
V
D
P
D
S
L
K
N
V
I
A
R
Site 31
S288
P
I
V
H
F
C
S
S
K
P
R
V
E
Y
S
Site 32
Y294
S
S
K
P
R
V
E
Y
S
T
K
I
V
E
V
Site 33
S295
S
K
P
R
V
E
Y
S
T
K
I
V
E
V
F
Site 34
T296
K
P
R
V
E
Y
S
T
K
I
V
E
V
F
C
Site 35
S330
V
F
S
E
A
P
K
S
W
M
V
R
E
K
Y
Site 36
Y337
S
W
M
V
R
E
K
Y
I
R
P
L
T
T
E
Site 37
T342
E
K
Y
I
R
P
L
T
T
E
E
W
V
E
K
Site 38
S367
D
F
A
E
A
F
E
S
Q
L
S
L
S
D
S
Site 39
S370
E
A
F
E
S
Q
L
S
L
S
D
S
P
S
L
Site 40
S372
F
E
S
Q
L
S
L
S
D
S
P
S
L
C
R
Site 41
S374
S
Q
L
S
L
S
D
S
P
S
L
C
R
P
V
Site 42
S376
L
S
L
S
D
S
P
S
L
C
R
P
V
Y
S
Site 43
Y382
P
S
L
C
R
P
V
Y
S
K
K
G
L
E
H
Site 44
S383
S
L
C
R
P
V
Y
S
K
K
G
L
E
H
K
Site 45
T408
P
P
G
H
L
E
C
T
P
E
S
L
W
K
E
Site 46
S411
H
L
E
C
T
P
E
S
L
W
K
E
L
S
L
Site 47
S417
E
S
L
W
K
E
L
S
L
Q
H
E
G
L
K
Site 48
S435
H
K
Q
M
R
P
F
S
Q
G
I
V
I
L
S
Site 49
Y486
Q
D
A
E
G
Q
D
Y
C
T
R
T
A
F
T
Site 50
T488
A
E
G
Q
D
Y
C
T
R
T
A
F
T
L
K
Site 51
S518
R
A
K
V
L
C
L
S
P
E
S
S
A
E
A
Site 52
S531
E
A
L
E
A
A
V
S
P
M
D
Y
P
A
S
Site 53
S538
S
P
M
D
Y
P
A
S
Y
S
L
A
G
T
Q
Site 54
S540
M
D
Y
P
A
S
Y
S
L
A
G
T
Q
H
M
Site 55
Y582
N
L
L
T
A
Q
Q
Y
E
I
F
S
R
S
L
Site 56
S588
Q
Y
E
I
F
S
R
S
L
R
K
N
R
E
L
Site 57
Y629
C
E
A
H
R
I
L
Y
V
C
E
N
Q
P
L
Site 58
S641
Q
P
L
R
N
F
I
S
D
R
N
I
C
R
A
Site 59
T650
R
N
I
C
R
A
E
T
R
E
T
F
L
R
E
Site 60
T653
C
R
A
E
T
R
E
T
F
L
R
E
K
F
E
Site 61
Y681
R
T
E
D
G
D
W
Y
R
K
A
K
T
I
T
Site 62
T688
Y
R
K
A
K
T
I
T
Q
R
E
K
D
C
P
Site 63
S713
Q
T
S
H
L
G
H
S
G
L
P
P
L
S
A
Site 64
S719
H
S
G
L
P
P
L
S
A
Q
Y
P
R
E
E
Site 65
Y722
L
P
P
L
S
A
Q
Y
P
R
E
E
L
T
R
Site 66
Y740
N
A
D
E
I
A
E
Y
I
Q
Q
E
M
Q
L
Site 67
Y804
R
C
F
F
E
R
G
Y
S
P
K
D
V
A
V
Site 68
Y822
T
V
T
E
V
E
Q
Y
Q
S
K
L
L
K
A
Site 69
S858
L
D
S
V
R
R
F
S
G
L
E
R
S
I
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation