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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KCTD16
Full Name:
BTB/POZ domain-containing protein KCTD16
Alias:
BTB/POZ domain-containing KCTD16; KCD16
Type:
Membrane, Voltage-gated potassium channel complex protein
Mass (Da):
49138
Number AA:
428
UniProt ID:
Q68DU8
International Prot ID:
IPI00002354
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0008076
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005249
PhosphoSite+
KinaseNET
Biological Process:
GO:0006813
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
L
S
G
N
C
S
R
Y
Y
P
R
E
Q
Site 2
Y10
L
S
G
N
C
S
R
Y
Y
P
R
E
Q
G
S
Site 3
Y11
S
G
N
C
S
R
Y
Y
P
R
E
Q
G
S
A
Site 4
S22
Q
G
S
A
V
P
N
S
F
P
E
V
V
E
L
Site 5
Y36
L
N
V
G
G
Q
V
Y
F
T
R
H
S
T
L
Site 6
S41
Q
V
Y
F
T
R
H
S
T
L
I
S
I
P
H
Site 7
T42
V
Y
F
T
R
H
S
T
L
I
S
I
P
H
S
Site 8
S56
S
L
L
W
K
M
F
S
P
K
R
D
T
A
N
Site 9
T61
M
F
S
P
K
R
D
T
A
N
D
L
A
K
D
Site 10
S69
A
N
D
L
A
K
D
S
K
G
R
F
F
I
D
Site 11
Y84
R
D
G
F
L
F
R
Y
I
L
D
Y
L
R
D
Site 12
Y88
L
F
R
Y
I
L
D
Y
L
R
D
R
Q
V
V
Site 13
Y112
R
L
K
R
E
A
E
Y
F
Q
L
P
D
L
V
Site 14
T123
P
D
L
V
K
L
L
T
P
D
E
I
K
Q
S
Site 15
S130
T
P
D
E
I
K
Q
S
P
D
E
F
C
H
S
Site 16
S137
S
P
D
E
F
C
H
S
D
F
E
D
A
S
Q
Site 17
S143
H
S
D
F
E
D
A
S
Q
G
S
D
T
R
I
Site 18
S146
F
E
D
A
S
Q
G
S
D
T
R
I
C
P
P
Site 19
T148
D
A
S
Q
G
S
D
T
R
I
C
P
P
S
S
Site 20
S154
D
T
R
I
C
P
P
S
S
L
L
P
A
D
R
Site 21
S155
T
R
I
C
P
P
S
S
L
L
P
A
D
R
K
Site 22
T167
D
R
K
W
G
F
I
T
V
G
Y
R
G
S
C
Site 23
S173
I
T
V
G
Y
R
G
S
C
T
L
G
R
E
G
Site 24
T175
V
G
Y
R
G
S
C
T
L
G
R
E
G
Q
A
Site 25
Y222
P
D
R
A
P
E
R
Y
T
S
R
F
Y
L
K
Site 26
T223
D
R
A
P
E
R
Y
T
S
R
F
Y
L
K
F
Site 27
S224
R
A
P
E
R
Y
T
S
R
F
Y
L
K
F
K
Site 28
Y227
E
R
Y
T
S
R
F
Y
L
K
F
K
H
L
E
Site 29
S257
C
N
S
S
V
T
A
S
F
I
N
Q
Y
T
D
Site 30
T263
A
S
F
I
N
Q
Y
T
D
D
K
I
W
S
S
Site 31
Y271
D
D
K
I
W
S
S
Y
T
E
Y
V
F
Y
R
Site 32
Y274
I
W
S
S
Y
T
E
Y
V
F
Y
R
E
P
S
Site 33
Y277
S
Y
T
E
Y
V
F
Y
R
E
P
S
R
W
S
Site 34
S286
E
P
S
R
W
S
P
S
H
C
D
C
C
C
K
Site 35
S306
K
E
G
E
S
G
T
S
C
N
D
L
S
T
S
Site 36
S311
G
T
S
C
N
D
L
S
T
S
S
C
D
S
Q
Site 37
T312
T
S
C
N
D
L
S
T
S
S
C
D
S
Q
S
Site 38
S313
S
C
N
D
L
S
T
S
S
C
D
S
Q
S
E
Site 39
S314
C
N
D
L
S
T
S
S
C
D
S
Q
S
E
A
Site 40
S317
L
S
T
S
S
C
D
S
Q
S
E
A
S
S
P
Site 41
S319
T
S
S
C
D
S
Q
S
E
A
S
S
P
Q
E
Site 42
S323
D
S
Q
S
E
A
S
S
P
Q
E
T
V
I
C
Site 43
T327
E
A
S
S
P
Q
E
T
V
I
C
G
P
V
T
Site 44
T337
C
G
P
V
T
R
Q
T
N
I
Q
T
L
D
R
Site 45
S357
P
V
Q
L
I
Q
Q
S
E
M
R
R
K
S
D
Site 46
S363
Q
S
E
M
R
R
K
S
D
L
L
R
T
L
T
Site 47
T368
R
K
S
D
L
L
R
T
L
T
S
G
S
R
E
Site 48
T370
S
D
L
L
R
T
L
T
S
G
S
R
E
S
N
Site 49
S371
D
L
L
R
T
L
T
S
G
S
R
E
S
N
M
Site 50
S373
L
R
T
L
T
S
G
S
R
E
S
N
M
S
S
Site 51
S376
L
T
S
G
S
R
E
S
N
M
S
S
K
K
K
Site 52
S379
G
S
R
E
S
N
M
S
S
K
K
K
A
V
K
Site 53
S380
S
R
E
S
N
M
S
S
K
K
K
A
V
K
E
Site 54
S390
K
A
V
K
E
K
L
S
I
E
E
E
L
E
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation