PhosphoNET

           
Protein Info 
   
Short Name:  RNF43
Full Name:  RING finger protein 43
Alias: 
Type: 
Mass (Da):  85722
Number AA:  783
UniProt ID:  Q68DV7
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S227IRCRPRHSRPDPLQQ
Site 2S241QRTAWAISQLATRRY
Site 3T245WAISQLATRRYQASC
Site 4Y248SQLATRRYQASCRQA
Site 5S251ATRRYQASCRQARGE
Site 6S262ARGEWPDSGSSCSSA
Site 7S264GEWPDSGSSCSSAPV
Site 8S265EWPDSGSSCSSAPVC
Site 9S289GQELRVISCLHEFHR
Site 10T317PLCMFNITEGDSFSQ
Site 11S321FNITEGDSFSQSLGP
Site 12S323ITEGDSFSQSLGPSR
Site 13S325EGDSFSQSLGPSRSY
Site 14S329FSQSLGPSRSYQEPG
Site 15S331QSLGPSRSYQEPGRR
Site 16Y332SLGPSRSYQEPGRRL
Site 17Y351QHPGHAHYHLPAAYL
Site 18S364YLLGPSRSAVARPPR
Site 19S378RPGPFLPSQEPGMGP
Site 20Y412LAGAQHPYAQGWGLS
Site 21S419YAQGWGLSHLQSTSQ
Site 22S423WGLSHLQSTSQHPAA
Site 23S425LSHLQSTSQHPAACP
Site 24S443RRARPPDSSGSGESY
Site 25S444RARPPDSSGSGESYC
Site 26S446RPPDSSGSGESYCTE
Site 27S449DSSGSGESYCTERSG
Site 28Y450SSGSGESYCTERSGY
Site 29T452GSGESYCTERSGYLA
Site 30Y457YCTERSGYLADGPAS
Site 31S464YLADGPASDSSSGPC
Site 32S466ADGPASDSSSGPCHG
Site 33S467DGPASDSSSGPCHGS
Site 34S468GPASDSSSGPCHGSS
Site 35S474SSGPCHGSSSDSVVN
Site 36S475SGPCHGSSSDSVVNC
Site 37S476GPCHGSSSDSVVNCT
Site 38S478CHGSSSDSVVNCTDI
Site 39S493SLQGVHGSSSTFCSS
Site 40S495QGVHGSSSTFCSSLS
Site 41T496GVHGSSSTFCSSLSS
Site 42S499GSSSTFCSSLSSDFD
Site 43S500SSSTFCSSLSSDFDP
Site 44Y510SDFDPLVYCSPKGDP
Site 45S512FDPLVYCSPKGDPQR
Site 46S525QRVDMQPSVTSRPRS
Site 47T527VDMQPSVTSRPRSLD
Site 48S528DMQPSVTSRPRSLDS
Site 49S532SVTSRPRSLDSVVPT
Site 50S535SRPRSLDSVVPTGET
Site 51T539SLDSVVPTGETQVSS
Site 52T542SVVPTGETQVSSHVH
Site 53S545PTGETQVSSHVHYHR
Site 54T573GRKPGPETGVPQSRP
Site 55S578PETGVPQSRPPIPRT
Site 56T585SRPPIPRTQPQPEPP
Site 57S593QPQPEPPSPDQQVTR
Site 58T599PSPDQQVTRSNSAAP
Site 59S601PDQQVTRSNSAAPSG
Site 60S603QQVTRSNSAAPSGRL
Site 61S607RSNSAAPSGRLSNPQ
Site 62S611AAPSGRLSNPQCPRA
Site 63S631PGPVDASSICPSTSS
Site 64S637SSICPSTSSLFNLQK
Site 65S638SICPSTSSLFNLQKS
Site 66S645SLFNLQKSSLSARHP
Site 67S646LFNLQKSSLSARHPQ
Site 68S648NLQKSSLSARHPQRK
Site 69S661RKRRGGPSEPTPGSR
Site 70T664RGGPSEPTPGSRPQD
Site 71S667PSEPTPGSRPQDATV
Site 72T673GSRPQDATVHPACQI
Site 73Y690HYTPSVAYPWSPEAH
Site 74S693PSVAYPWSPEAHPLI
Site 75T714DKRLLPETPGPCYSN
Site 76Y719PETPGPCYSNSQPVW
Site 77S720ETPGPCYSNSQPVWL
Site 78T730QPVWLCLTPRQPLEP
Site 79S745HPPGEGPSEWSSDTA
Site 80S749EGPSEWSSDTAEGRP
Site 81T751PSEWSSDTAEGRPCP
Site 82Y759AEGRPCPYPHCQVLS
Site 83S766YPHCQVLSAQPGSEE
Site 84S771VLSAQPGSEEELEEL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation