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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF57
Full Name:
Zinc finger protein 57
Alias:
LOC126295; Zinc finger protein 424; ZNF424
Type:
Transcription factor
Mass (Da):
64428
Number AA:
1076
UniProt ID:
Q68EA5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
E
E
W
A
L
L
D
S
A
Q
R
D
L
Y
R
Site 2
Y29
D
S
A
Q
R
D
L
Y
R
D
V
M
L
E
T
Site 3
T36
Y
R
D
V
M
L
E
T
F
R
N
L
A
S
V
Site 4
S42
E
T
F
R
N
L
A
S
V
D
D
G
T
Q
F
Site 5
T47
L
A
S
V
D
D
G
T
Q
F
K
A
N
G
S
Site 6
S54
T
Q
F
K
A
N
G
S
V
S
L
Q
D
M
Y
Site 7
S56
F
K
A
N
G
S
V
S
L
Q
D
M
Y
G
Q
Site 8
Y61
S
V
S
L
Q
D
M
Y
G
Q
E
K
S
K
E
Site 9
S66
D
M
Y
G
Q
E
K
S
K
E
Q
T
I
P
N
Site 10
T70
Q
E
K
S
K
E
Q
T
I
P
N
F
T
G
N
Site 11
T75
E
Q
T
I
P
N
F
T
G
N
N
S
C
A
Y
Site 12
T83
G
N
N
S
C
A
Y
T
L
E
K
N
C
E
G
Site 13
Y117
T
H
N
E
G
N
Q
Y
G
E
A
I
H
Q
M
Site 14
T128
I
H
Q
M
P
D
L
T
L
H
K
K
V
S
A
Site 15
S134
L
T
L
H
K
K
V
S
A
G
E
K
P
Y
E
Site 16
T150
T
K
C
R
T
V
F
T
H
L
S
S
L
K
R
Site 17
S153
R
T
V
F
T
H
L
S
S
L
K
R
H
V
K
Site 18
S154
T
V
F
T
H
L
S
S
L
K
R
H
V
K
S
Site 19
S161
S
L
K
R
H
V
K
S
H
C
G
R
K
A
P
Site 20
S185
I
C
P
S
H
L
H
S
H
G
R
T
D
T
E
Site 21
T189
H
L
H
S
H
G
R
T
D
T
E
E
K
P
Y
Site 22
T191
H
S
H
G
R
T
D
T
E
E
K
P
Y
K
C
Site 23
Y196
T
D
T
E
E
K
P
Y
K
C
Q
A
C
G
Q
Site 24
Y210
Q
T
F
Q
H
P
R
Y
L
S
H
H
V
K
T
Site 25
T223
K
T
H
T
A
E
K
T
Y
K
C
E
Q
C
R
Site 26
T247
T
R
H
V
R
T
H
T
K
D
R
P
Y
K
C
Site 27
Y252
T
H
T
K
D
R
P
Y
K
C
Q
E
C
G
R
Site 28
Y263
E
C
G
R
A
F
I
Y
P
S
T
F
Q
R
H
Site 29
T272
S
T
F
Q
R
H
M
T
T
H
T
G
E
K
P
Site 30
Y280
T
H
T
G
E
K
P
Y
K
C
Q
H
C
G
K
Site 31
T301
A
F
Q
R
H
E
K
T
H
T
G
E
K
P
Y
Site 32
T303
Q
R
H
E
K
T
H
T
G
E
K
P
Y
E
C
Site 33
Y308
T
H
T
G
E
K
P
Y
E
C
K
Q
C
G
K
Site 34
T316
E
C
K
Q
C
G
K
T
F
S
W
S
E
T
L
Site 35
S318
K
Q
C
G
K
T
F
S
W
S
E
T
L
R
V
Site 36
T322
K
T
F
S
W
S
E
T
L
R
V
H
M
R
I
Site 37
T331
R
V
H
M
R
I
H
T
G
D
K
L
Y
K
C
Site 38
Y336
I
H
T
G
D
K
L
Y
K
C
E
H
C
G
K
Site 39
T346
E
H
C
G
K
A
F
T
S
S
R
S
F
Q
G
Site 40
S347
H
C
G
K
A
F
T
S
S
R
S
F
Q
G
H
Site 41
S348
C
G
K
A
F
T
S
S
R
S
F
Q
G
H
L
Site 42
S350
K
A
F
T
S
S
R
S
F
Q
G
H
L
R
T
Site 43
T357
S
F
Q
G
H
L
R
T
H
T
G
E
K
P
Y
Site 44
T359
Q
G
H
L
R
T
H
T
G
E
K
P
Y
E
C
Site 45
S377
G
K
A
F
T
W
S
S
T
F
R
E
H
V
R
Site 46
T378
K
A
F
T
W
S
S
T
F
R
E
H
V
R
I
Site 47
T387
R
E
H
V
R
I
H
T
Q
E
Q
L
Y
K
C
Site 48
Y392
I
H
T
Q
E
Q
L
Y
K
C
E
Q
C
G
K
Site 49
T402
E
Q
C
G
K
A
F
T
S
S
R
S
F
R
G
Site 50
S403
Q
C
G
K
A
F
T
S
S
R
S
F
R
G
H
Site 51
S404
C
G
K
A
F
T
S
S
R
S
F
R
G
H
L
Site 52
S406
K
A
F
T
S
S
R
S
F
R
G
H
L
R
T
Site 53
T413
S
F
R
G
H
L
R
T
H
T
G
E
K
P
Y
Site 54
T415
R
G
H
L
R
T
H
T
G
E
K
P
Y
E
C
Site 55
S433
G
K
T
F
T
W
S
S
T
F
R
E
H
V
R
Site 56
T434
K
T
F
T
W
S
S
T
F
R
E
H
V
R
I
Site 57
T443
R
E
H
V
R
I
H
T
Q
E
Q
L
H
K
C
Site 58
S460
C
G
K
A
F
T
S
S
R
A
F
Q
G
H
L
Site 59
T471
Q
G
H
L
R
M
H
T
G
E
K
P
Y
E
C
Site 60
Y476
M
H
T
G
E
K
P
Y
E
C
K
Q
C
G
K
Site 61
T484
E
C
K
Q
C
G
K
T
F
T
W
S
S
T
L
Site 62
T499
H
N
H
V
R
M
H
T
G
E
K
P
H
K
C
Site 63
T527
R
N
H
L
R
M
H
T
G
Q
K
S
H
E
C
Site 64
S536
Q
K
S
H
E
C
Q
S
Y
S
K
A
F
S
C
Site 65
Y537
K
S
H
E
C
Q
S
Y
S
K
A
F
S
C
Q
Site 66
S542
Q
S
Y
S
K
A
F
S
C
Q
V
I
L
S
K
Site 67
S548
F
S
C
Q
V
I
L
S
K
T
S
E
S
T
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation