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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CYTSA
Full Name:
Cytospin-A
Alias:
Cytokinesis and spindle organization A; Cytospin A; KIAA0376; LOC23384; SPECC1L; SPECC1-like protein
Type:
Cell cycle regulation
Mass (Da):
124592
Number AA:
1117
UniProt ID:
Q69YQ0
International Prot ID:
IPI00178072
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005882;
Uniprot
OncoNet
Molecular Function:
GO:0005198;
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0051301
GO:0051301
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
K
K
A
S
R
S
V
G
S
V
P
K
V
Site 2
S10
K
A
S
R
S
V
G
S
V
P
K
V
S
A
I
Site 3
T20
K
V
S
A
I
S
K
T
Q
T
A
E
K
I
K
Site 4
T22
S
A
I
S
K
T
Q
T
A
E
K
I
K
P
E
Site 5
S31
E
K
I
K
P
E
N
S
S
S
A
S
T
G
G
Site 6
S33
I
K
P
E
N
S
S
S
A
S
T
G
G
K
L
Site 7
S35
P
E
N
S
S
S
A
S
T
G
G
K
L
V
K
Site 8
T45
G
K
L
V
K
P
G
T
A
A
S
L
S
K
T
Site 9
S48
V
K
P
G
T
A
A
S
L
S
K
T
K
S
S
Site 10
S50
P
G
T
A
A
S
L
S
K
T
K
S
S
D
D
Site 11
T52
T
A
A
S
L
S
K
T
K
S
S
D
D
L
L
Site 12
S54
A
S
L
S
K
T
K
S
S
D
D
L
L
A
G
Site 13
S55
S
L
S
K
T
K
S
S
D
D
L
L
A
G
M
Site 14
T69
M
A
G
G
V
T
V
T
N
G
V
K
G
K
K
Site 15
S77
N
G
V
K
G
K
K
S
T
C
P
S
A
A
P
Site 16
S81
G
K
K
S
T
C
P
S
A
A
P
S
A
S
A
Site 17
T93
A
S
A
P
A
M
T
T
V
E
N
K
S
K
I
Site 18
S98
M
T
T
V
E
N
K
S
K
I
S
T
G
T
A
Site 19
T102
E
N
K
S
K
I
S
T
G
T
A
S
S
T
K
Site 20
S106
K
I
S
T
G
T
A
S
S
T
K
R
S
T
S
Site 21
S107
I
S
T
G
T
A
S
S
T
K
R
S
T
S
T
Site 22
T108
S
T
G
T
A
S
S
T
K
R
S
T
S
T
G
Site 23
S111
T
A
S
S
T
K
R
S
T
S
T
G
N
K
E
Site 24
T112
A
S
S
T
K
R
S
T
S
T
G
N
K
E
S
Site 25
S113
S
S
T
K
R
S
T
S
T
G
N
K
E
S
S
Site 26
T114
S
T
K
R
S
T
S
T
G
N
K
E
S
S
S
Site 27
S120
S
T
G
N
K
E
S
S
S
T
R
E
R
L
R
Site 28
S121
T
G
N
K
E
S
S
S
T
R
E
R
L
R
E
Site 29
T122
G
N
K
E
S
S
S
T
R
E
R
L
R
E
R
Site 30
T130
R
E
R
L
R
E
R
T
R
L
N
Q
S
K
K
Site 31
S156
A
L
A
K
R
S
R
S
R
T
A
T
E
C
D
Site 32
T158
A
K
R
S
R
S
R
T
A
T
E
C
D
V
R
Site 33
T160
R
S
R
S
R
T
A
T
E
C
D
V
R
M
S
Site 34
S167
T
E
C
D
V
R
M
S
K
S
K
S
D
N
Q
Site 35
S169
C
D
V
R
M
S
K
S
K
S
D
N
Q
I
S
Site 36
S171
V
R
M
S
K
S
K
S
D
N
Q
I
S
D
R
Site 37
S176
S
K
S
D
N
Q
I
S
D
R
A
A
L
E
A
Site 38
T190
A
K
V
K
D
L
L
T
L
A
K
T
K
D
V
Site 39
S220
L
G
I
N
E
D
H
S
E
G
D
E
K
S
E
Site 40
S226
H
S
E
G
D
E
K
S
E
K
E
T
I
M
A
Site 41
S277
R
L
N
A
L
G
F
S
L
E
Q
R
L
D
N
Site 42
S285
L
E
Q
R
L
D
N
S
E
K
L
F
G
Y
Q
Site 43
Y291
N
S
E
K
L
F
G
Y
Q
S
L
S
P
E
I
Site 44
S293
E
K
L
F
G
Y
Q
S
L
S
P
E
I
T
P
Site 45
S295
L
F
G
Y
Q
S
L
S
P
E
I
T
P
G
N
Site 46
T299
Q
S
L
S
P
E
I
T
P
G
N
Q
S
D
G
Site 47
S304
E
I
T
P
G
N
Q
S
D
G
G
G
T
L
T
Site 48
T309
N
Q
S
D
G
G
G
T
L
T
S
S
V
E
G
Site 49
T311
S
D
G
G
G
T
L
T
S
S
V
E
G
S
A
Site 50
S312
D
G
G
G
T
L
T
S
S
V
E
G
S
A
P
Site 51
S313
G
G
G
T
L
T
S
S
V
E
G
S
A
P
G
Site 52
S317
L
T
S
S
V
E
G
S
A
P
G
S
V
E
D
Site 53
S321
V
E
G
S
A
P
G
S
V
E
D
L
L
S
Q
Site 54
S327
G
S
V
E
D
L
L
S
Q
D
E
N
T
L
M
Site 55
T332
L
L
S
Q
D
E
N
T
L
M
D
H
Q
H
S
Site 56
S341
M
D
H
Q
H
S
N
S
M
D
N
L
D
S
E
Site 57
S347
N
S
M
D
N
L
D
S
E
C
S
E
V
Y
Q
Site 58
S350
D
N
L
D
S
E
C
S
E
V
Y
Q
P
L
T
Site 59
Y353
D
S
E
C
S
E
V
Y
Q
P
L
T
S
S
D
Site 60
T357
S
E
V
Y
Q
P
L
T
S
S
D
D
A
L
D
Site 61
S359
V
Y
Q
P
L
T
S
S
D
D
A
L
D
A
P
Site 62
S367
D
D
A
L
D
A
P
S
S
S
E
S
E
G
I
Site 63
S368
D
A
L
D
A
P
S
S
S
E
S
E
G
I
L
Site 64
S369
A
L
D
A
P
S
S
S
E
S
E
G
I
L
S
Site 65
S371
D
A
P
S
S
S
E
S
E
G
I
L
S
I
E
Site 66
S376
S
E
S
E
G
I
L
S
I
E
R
S
R
K
G
Site 67
S380
G
I
L
S
I
E
R
S
R
K
G
S
S
G
N
Site 68
S384
I
E
R
S
R
K
G
S
S
G
N
A
S
E
V
Site 69
S385
E
R
S
R
K
G
S
S
G
N
A
S
E
V
S
Site 70
S389
K
G
S
S
G
N
A
S
E
V
S
V
A
C
L
Site 71
S392
S
G
N
A
S
E
V
S
V
A
C
L
T
E
R
Site 72
T397
E
V
S
V
A
C
L
T
E
R
I
H
Q
M
E
Site 73
S409
Q
M
E
E
N
Q
H
S
T
S
E
E
L
Q
A
Site 74
T417
T
S
E
E
L
Q
A
T
L
Q
E
L
A
D
L
Site 75
S448
E
K
V
I
L
M
E
S
L
C
Q
Q
S
D
K
Site 76
Y465
H
F
S
R
Q
I
E
Y
F
R
S
L
L
D
E
Site 77
S468
R
Q
I
E
Y
F
R
S
L
L
D
E
H
H
I
Site 78
S476
L
L
D
E
H
H
I
S
Y
V
I
D
E
D
V
Site 79
Y477
L
D
E
H
H
I
S
Y
V
I
D
E
D
V
K
Site 80
S485
V
I
D
E
D
V
K
S
G
R
Y
M
E
L
E
Site 81
S517
L
G
V
Q
Q
H
L
S
N
T
L
K
M
A
E
Site 82
T568
T
L
E
E
Y
K
A
T
V
A
S
D
Q
I
E
Site 83
S571
E
Y
K
A
T
V
A
S
D
Q
I
E
M
N
R
Site 84
Y594
K
Q
K
V
A
E
L
Y
S
I
H
N
S
G
D
Site 85
S595
Q
K
V
A
E
L
Y
S
I
H
N
S
G
D
K
Site 86
S599
E
L
Y
S
I
H
N
S
G
D
K
S
D
I
Q
Site 87
S603
I
H
N
S
G
D
K
S
D
I
Q
D
L
L
E
Site 88
S611
D
I
Q
D
L
L
E
S
V
R
L
D
K
E
K
Site 89
T621
L
D
K
E
K
A
E
T
L
A
S
S
L
Q
E
Site 90
S624
E
K
A
E
T
L
A
S
S
L
Q
E
D
L
A
Site 91
S625
K
A
E
T
L
A
S
S
L
Q
E
D
L
A
H
Site 92
Y651
I
A
K
V
E
D
E
Y
R
A
F
Q
E
E
A
Site 93
S674
M
T
L
E
K
L
R
S
D
L
D
E
K
E
T
Site 94
S684
D
E
K
E
T
E
R
S
D
M
K
E
T
I
F
Site 95
S712
L
H
D
N
L
I
I
S
D
L
E
N
T
V
K
Site 96
T734
D
M
E
R
E
I
K
T
L
H
R
R
L
R
E
Site 97
S743
H
R
R
L
R
E
E
S
A
E
W
R
Q
F
Q
Site 98
S765
V
I
A
N
D
I
K
S
E
A
Q
E
E
I
G
Site 99
S797
K
E
L
E
E
I
K
S
R
K
Q
E
E
E
R
Site 100
Y808
E
E
E
R
G
R
V
Y
N
Y
M
N
A
V
E
Site 101
Y810
E
R
G
R
V
Y
N
Y
M
N
A
V
E
R
D
Site 102
S828
L
R
Q
G
M
G
L
S
R
R
S
S
T
S
S
Site 103
S831
G
M
G
L
S
R
R
S
S
T
S
S
E
P
T
Site 104
S832
M
G
L
S
R
R
S
S
T
S
S
E
P
T
P
Site 105
T833
G
L
S
R
R
S
S
T
S
S
E
P
T
P
T
Site 106
S834
L
S
R
R
S
S
T
S
S
E
P
T
P
T
V
Site 107
S835
S
R
R
S
S
T
S
S
E
P
T
P
T
V
K
Site 108
T838
S
S
T
S
S
E
P
T
P
T
V
K
T
L
I
Site 109
T840
T
S
S
E
P
T
P
T
V
K
T
L
I
K
S
Site 110
T843
E
P
T
P
T
V
K
T
L
I
K
S
F
D
S
Site 111
S847
T
V
K
T
L
I
K
S
F
D
S
A
S
Q
V
Site 112
S850
T
L
I
K
S
F
D
S
A
S
Q
V
P
N
P
Site 113
S852
I
K
S
F
D
S
A
S
Q
V
P
N
P
A
A
Site 114
S868
A
I
P
R
T
P
L
S
P
S
P
M
K
T
P
Site 115
S870
P
R
T
P
L
S
P
S
P
M
K
T
P
P
A
Site 116
T874
L
S
P
S
P
M
K
T
P
P
A
A
A
V
S
Site 117
S881
T
P
P
A
A
A
V
S
P
M
Q
R
H
S
I
Site 118
S887
V
S
P
M
Q
R
H
S
I
S
G
P
I
S
T
Site 119
S889
P
M
Q
R
H
S
I
S
G
P
I
S
T
S
K
Site 120
S893
H
S
I
S
G
P
I
S
T
S
K
P
L
T
A
Site 121
T899
I
S
T
S
K
P
L
T
A
L
S
D
K
R
P
Site 122
S902
S
K
P
L
T
A
L
S
D
K
R
P
N
Y
G
Site 123
Y908
L
S
D
K
R
P
N
Y
G
E
I
P
V
Q
E
Site 124
T920
V
Q
E
H
L
L
R
T
S
S
A
S
R
P
A
Site 125
S921
Q
E
H
L
L
R
T
S
S
A
S
R
P
A
S
Site 126
S922
E
H
L
L
R
T
S
S
A
S
R
P
A
S
L
Site 127
S924
L
L
R
T
S
S
A
S
R
P
A
S
L
P
R
Site 128
S928
S
S
A
S
R
P
A
S
L
P
R
V
P
A
M
Site 129
S937
P
R
V
P
A
M
E
S
A
K
T
L
S
V
S
Site 130
T940
P
A
M
E
S
A
K
T
L
S
V
S
R
R
S
Site 131
S942
M
E
S
A
K
T
L
S
V
S
R
R
S
S
E
Site 132
S944
S
A
K
T
L
S
V
S
R
R
S
S
E
E
M
Site 133
S947
T
L
S
V
S
R
R
S
S
E
E
M
K
R
D
Site 134
S948
L
S
V
S
R
R
S
S
E
E
M
K
R
D
I
Site 135
S956
E
E
M
K
R
D
I
S
A
Q
E
G
A
S
P
Site 136
S965
Q
E
G
A
S
P
A
S
L
M
A
M
G
T
T
Site 137
S973
L
M
A
M
G
T
T
S
P
Q
L
S
L
S
S
Site 138
S977
G
T
T
S
P
Q
L
S
L
S
S
S
P
T
A
Site 139
S979
T
S
P
Q
L
S
L
S
S
S
P
T
A
S
V
Site 140
S980
S
P
Q
L
S
L
S
S
S
P
T
A
S
V
T
Site 141
S981
P
Q
L
S
L
S
S
S
P
T
A
S
V
T
P
Site 142
T983
L
S
L
S
S
S
P
T
A
S
V
T
P
T
T
Site 143
S985
L
S
S
S
P
T
A
S
V
T
P
T
T
R
S
Site 144
T987
S
S
P
T
A
S
V
T
P
T
T
R
S
R
I
Site 145
T989
P
T
A
S
V
T
P
T
T
R
S
R
I
R
E
Site 146
S992
S
V
T
P
T
T
R
S
R
I
R
E
E
R
K
Site 147
S1003
E
E
R
K
D
P
L
S
A
L
A
R
E
Y
G
Site 148
Y1009
L
S
A
L
A
R
E
Y
G
G
S
K
R
N
A
Site 149
S1012
L
A
R
E
Y
G
G
S
K
R
N
A
L
L
K
Site 150
S1039
D
I
T
N
F
S
S
S
W
N
D
G
L
A
F
Site 151
S1065
I
P
Y
Q
E
L
N
S
Q
D
K
R
R
N
F
Site 152
S1081
L
A
F
Q
A
A
E
S
V
G
I
K
S
T
L
Site 153
S1086
A
E
S
V
G
I
K
S
T
L
D
I
N
E
M
Site 154
Y1107
D
W
Q
N
V
M
L
Y
V
T
A
I
Y
K
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation