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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KRT40
Full Name:
Keratin, type I cytoskeletal 40
Alias:
Cytokeratin-40;Keratin-40;Type I hair keratin Ka36
Type:
Mass (Da):
48139
Number AA:
431
UniProt ID:
Q6A162
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
T
S
D
C
S
S
T
H
C
S
P
E
S
Site 2
T8
M
T
S
D
C
S
S
T
H
C
S
P
E
S
C
Site 3
S11
D
C
S
S
T
H
C
S
P
E
S
C
G
T
A
Site 4
S14
S
T
H
C
S
P
E
S
C
G
T
A
S
G
C
Site 5
T17
C
S
P
E
S
C
G
T
A
S
G
C
A
P
A
Site 6
S19
P
E
S
C
G
T
A
S
G
C
A
P
A
S
S
Site 7
T37
E
T
A
C
L
P
G
T
C
A
T
S
R
C
Q
Site 8
S41
L
P
G
T
C
A
T
S
R
C
Q
T
P
S
F
Site 9
T45
C
A
T
S
R
C
Q
T
P
S
F
L
S
R
S
Site 10
S47
T
S
R
C
Q
T
P
S
F
L
S
R
S
R
G
Site 11
S50
C
Q
T
P
S
F
L
S
R
S
R
G
L
T
G
Site 12
S52
T
P
S
F
L
S
R
S
R
G
L
T
G
C
L
Site 13
S102
F
L
N
D
R
L
A
S
Y
L
E
K
V
R
S
Site 14
Y103
L
N
D
R
L
A
S
Y
L
E
K
V
R
S
L
Site 15
S109
S
Y
L
E
K
V
R
S
L
E
E
T
N
A
E
Site 16
T113
K
V
R
S
L
E
E
T
N
A
E
L
E
S
R
Site 17
Y136
I
P
M
V
C
P
D
Y
Q
R
Y
F
N
T
I
Site 18
Y139
V
C
P
D
Y
Q
R
Y
F
N
T
I
E
D
L
Site 19
T171
L
D
N
C
K
L
A
T
D
D
F
K
S
K
Y
Site 20
S176
L
A
T
D
D
F
K
S
K
Y
E
S
E
L
S
Site 21
Y178
T
D
D
F
K
S
K
Y
E
S
E
L
S
L
R
Site 22
S180
D
F
K
S
K
Y
E
S
E
L
S
L
R
Q
L
Site 23
S183
S
K
Y
E
S
E
L
S
L
R
Q
L
L
E
A
Site 24
T203
H
G
I
L
E
E
L
T
L
C
K
S
D
L
E
Site 25
S207
E
E
L
T
L
C
K
S
D
L
E
A
H
V
E
Site 26
S243
E
Q
L
G
D
R
L
S
V
E
L
D
T
A
P
Site 27
S294
L
N
Q
Q
Q
L
S
S
A
E
Q
L
Q
G
C
Site 28
T311
E
I
L
E
L
K
R
T
A
S
A
L
E
I
E
Site 29
S313
L
E
L
K
R
T
A
S
A
L
E
I
E
L
Q
Site 30
S324
I
E
L
Q
A
Q
Q
S
L
T
E
S
L
E
C
Site 31
S328
A
Q
Q
S
L
T
E
S
L
E
C
T
V
A
E
Site 32
T332
L
T
E
S
L
E
C
T
V
A
E
T
E
A
Q
Site 33
S342
E
T
E
A
Q
Y
S
S
Q
L
A
Q
I
Q
C
Site 34
Y372
L
E
R
Q
N
Q
E
Y
Q
V
L
L
D
V
K
Site 35
Y389
L
E
G
E
I
N
T
Y
W
G
L
L
D
S
E
Site 36
S395
T
Y
W
G
L
L
D
S
E
D
S
R
L
S
C
Site 37
S398
G
L
L
D
S
E
D
S
R
L
S
C
S
P
C
Site 38
S401
D
S
E
D
S
R
L
S
C
S
P
C
S
T
T
Site 39
S403
E
D
S
R
L
S
C
S
P
C
S
T
T
C
T
Site 40
S406
R
L
S
C
S
P
C
S
T
T
C
T
S
S
N
Site 41
T407
L
S
C
S
P
C
S
T
T
C
T
S
S
N
T
Site 42
T408
S
C
S
P
C
S
T
T
C
T
S
S
N
T
C
Site 43
T410
S
P
C
S
T
T
C
T
S
S
N
T
C
E
P
Site 44
T414
T
T
C
T
S
S
N
T
C
E
P
C
S
A
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation