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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MCTP2
Full Name:
Multiple C2 and transmembrane domain-containing protein 2
Alias:
Multiple C2 domains, transmembrane 2
Type:
Mass (Da):
99605
Number AA:
878
UniProt ID:
Q6DN12
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0019722
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
D
L
D
K
P
S
V
W
G
S
L
K
Q
Site 2
S11
D
K
P
S
V
W
G
S
L
K
Q
R
T
R
P
Site 3
S24
R
P
L
L
I
N
L
S
K
K
K
V
K
K
N
Site 4
S33
K
K
V
K
K
N
P
S
K
P
P
D
L
R
A
Site 5
S49
H
H
L
D
R
R
L
S
L
S
V
P
D
L
L
Site 6
Y68
L
A
P
E
G
R
P
Y
S
G
P
Q
S
S
Y
Site 7
S69
A
P
E
G
R
P
Y
S
G
P
Q
S
S
Y
T
Site 8
S73
R
P
Y
S
G
P
Q
S
S
Y
T
S
V
P
S
Site 9
S74
P
Y
S
G
P
Q
S
S
Y
T
S
V
P
S
S
Site 10
Y75
Y
S
G
P
Q
S
S
Y
T
S
V
P
S
S
L
Site 11
T76
S
G
P
Q
S
S
Y
T
S
V
P
S
S
L
S
Site 12
S77
G
P
Q
S
S
Y
T
S
V
P
S
S
L
S
T
Site 13
S80
S
S
Y
T
S
V
P
S
S
L
S
T
A
G
I
Site 14
S91
T
A
G
I
F
P
K
S
S
S
S
S
L
K
Q
Site 15
S92
A
G
I
F
P
K
S
S
S
S
S
L
K
Q
S
Site 16
S93
G
I
F
P
K
S
S
S
S
S
L
K
Q
S
E
Site 17
S94
I
F
P
K
S
S
S
S
S
L
K
Q
S
E
E
Site 18
S95
F
P
K
S
S
S
S
S
L
K
Q
S
E
E
E
Site 19
S99
S
S
S
S
L
K
Q
S
E
E
E
L
D
W
S
Site 20
S106
S
E
E
E
L
D
W
S
Q
E
E
A
S
H
L
Site 21
T118
S
H
L
H
V
V
E
T
D
S
E
E
A
Y
A
Site 22
S120
L
H
V
V
E
T
D
S
E
E
A
Y
A
S
P
Site 23
Y124
E
T
D
S
E
E
A
Y
A
S
P
A
E
R
R
Site 24
S126
D
S
E
E
A
Y
A
S
P
A
E
R
R
R
V
Site 25
S134
P
A
E
R
R
R
V
S
S
N
G
I
F
D
L
Site 26
S135
A
E
R
R
R
V
S
S
N
G
I
F
D
L
Q
Site 27
S166
G
S
S
D
L
N
A
S
M
T
S
Q
H
F
E
Site 28
T168
S
D
L
N
A
S
M
T
S
Q
H
F
E
E
Q
Site 29
S176
S
Q
H
F
E
E
Q
S
V
P
G
E
A
S
D
Site 30
S182
Q
S
V
P
G
E
A
S
D
G
L
S
N
L
P
Site 31
S186
G
E
A
S
D
G
L
S
N
L
P
S
P
F
A
Site 32
T197
S
P
F
A
Y
L
L
T
I
H
L
K
E
G
R
Site 33
T214
V
V
R
D
R
C
G
T
S
D
P
Y
V
K
F
Site 34
S215
V
R
D
R
C
G
T
S
D
P
Y
V
K
F
K
Site 35
Y218
R
C
G
T
S
D
P
Y
V
K
F
K
L
N
G
Site 36
T227
K
F
K
L
N
G
K
T
L
Y
K
S
K
V
I
Site 37
Y229
K
L
N
G
K
T
L
Y
K
S
K
V
I
Y
K
Site 38
S231
N
G
K
T
L
Y
K
S
K
V
I
Y
K
N
L
Site 39
Y235
L
Y
K
S
K
V
I
Y
K
N
L
N
P
V
W
Site 40
Y262
Q
K
L
R
V
K
V
Y
D
R
D
L
T
T
S
Site 41
T267
K
V
Y
D
R
D
L
T
T
S
D
F
M
G
S
Site 42
T268
V
Y
D
R
D
L
T
T
S
D
F
M
G
S
A
Site 43
S269
Y
D
R
D
L
T
T
S
D
F
M
G
S
A
F
Site 44
T287
S
D
L
E
L
N
R
T
T
E
H
I
L
K
L
Site 45
T288
D
L
E
L
N
R
T
T
E
H
I
L
K
L
E
Site 46
S299
L
K
L
E
D
P
N
S
L
E
D
D
M
G
V
Site 47
S326
D
F
K
R
H
R
W
S
N
R
K
R
L
S
A
Site 48
S332
W
S
N
R
K
R
L
S
A
S
K
S
S
L
I
Site 49
S334
N
R
K
R
L
S
A
S
K
S
S
L
I
R
N
Site 50
S336
K
R
L
S
A
S
K
S
S
L
I
R
N
L
R
Site 51
S337
R
L
S
A
S
K
S
S
L
I
R
N
L
R
L
Site 52
S345
L
I
R
N
L
R
L
S
E
S
L
K
K
N
Q
Site 53
S347
R
N
L
R
L
S
E
S
L
K
K
N
Q
L
W
Site 54
Y387
L
K
L
G
D
Q
R
Y
K
S
K
T
L
C
K
Site 55
S389
L
G
D
Q
R
Y
K
S
K
T
L
C
K
S
A
Site 56
T391
D
Q
R
Y
K
S
K
T
L
C
K
S
A
N
P
Site 57
S395
K
S
K
T
L
C
K
S
A
N
P
Q
W
Q
E
Site 58
T434
K
H
E
E
R
L
G
T
C
K
V
D
I
S
A
Site 59
S487
V
C
P
L
A
D
L
S
E
R
K
Q
I
T
Q
Site 60
T493
L
S
E
R
K
Q
I
T
Q
R
Y
C
L
Q
N
Site 61
Y496
R
K
Q
I
T
Q
R
Y
C
L
Q
N
S
L
K
Site 62
S501
Q
R
Y
C
L
Q
N
S
L
K
D
V
K
D
V
Site 63
S527
D
L
L
A
A
D
F
S
G
K
S
D
P
F
C
Site 64
S530
A
A
D
F
S
G
K
S
D
P
F
C
L
L
E
Site 65
T545
L
G
N
D
R
L
Q
T
H
T
V
Y
K
N
L
Site 66
T547
N
D
R
L
Q
T
H
T
V
Y
K
N
L
N
P
Site 67
Y549
R
L
Q
T
H
T
V
Y
K
N
L
N
P
E
W
Site 68
T574
I
H
D
V
L
E
V
T
V
F
D
E
D
G
D
Site 69
S596
K
V
A
I
P
L
L
S
I
R
D
G
Q
P
N
Site 70
Y605
R
D
G
Q
P
N
C
Y
V
L
K
N
K
D
L
Site 71
S634
I
Y
N
P
V
K
A
S
I
R
T
F
T
P
R
Site 72
T637
P
V
K
A
S
I
R
T
F
T
P
R
E
K
R
Site 73
T639
K
A
S
I
R
T
F
T
P
R
E
K
R
F
V
Site 74
S649
E
K
R
F
V
E
D
S
R
K
L
S
K
K
I
Site 75
S653
V
E
D
S
R
K
L
S
K
K
I
L
S
R
D
Site 76
S686
K
S
C
F
Q
W
E
S
T
L
R
S
T
I
A
Site 77
T687
S
C
F
Q
W
E
S
T
L
R
S
T
I
A
F
Site 78
S731
P
V
K
G
K
V
S
S
I
Q
D
S
Q
E
S
Site 79
S735
K
V
S
S
I
Q
D
S
Q
E
S
T
D
I
D
Site 80
S738
S
I
Q
D
S
Q
E
S
T
D
I
D
D
E
E
Site 81
T739
I
Q
D
S
Q
E
S
T
D
I
D
D
E
E
D
Site 82
S752
E
D
E
D
D
K
E
S
E
K
K
G
L
I
E
Site 83
S780
N
V
L
E
E
I
A
S
F
G
E
R
I
K
N
Site 84
Y818
L
Y
F
I
P
L
R
Y
I
I
L
I
W
G
I
Site 85
Y836
T
K
K
L
R
N
P
Y
S
I
D
N
N
E
L
Site 86
S837
K
K
L
R
N
P
Y
S
I
D
N
N
E
L
L
Site 87
S848
N
E
L
L
D
F
L
S
R
V
P
S
D
V
Q
Site 88
S852
D
F
L
S
R
V
P
S
D
V
Q
K
V
Q
Y
Site 89
Y859
S
D
V
Q
K
V
Q
Y
A
E
L
K
L
C
S
Site 90
S866
Y
A
E
L
K
L
C
S
S
H
S
P
L
R
K
Site 91
S867
A
E
L
K
L
C
S
S
H
S
P
L
R
K
K
Site 92
S869
L
K
L
C
S
S
H
S
P
L
R
K
K
R
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation