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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MCTP1
Full Name:
Multiple C2 and transmembrane domain-containing protein 1
Alias:
FLJ22344; multiple C2 domains, transmembrane 1
Type:
Mass (Da):
111620
Number AA:
UniProt ID:
Q6DN14
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0019722
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
E
P
P
A
A
S
S
S
F
Q
A
R
L
W
K
Site 2
S35
L
Q
L
G
V
G
R
S
K
G
G
G
G
G
R
Site 3
T50
A
G
G
P
E
R
R
T
A
D
T
P
S
P
S
Site 4
T53
P
E
R
R
T
A
D
T
P
S
P
S
P
P
P
Site 5
S55
R
R
T
A
D
T
P
S
P
S
P
P
P
P
V
Site 6
S57
T
A
D
T
P
S
P
S
P
P
P
P
V
G
T
Site 7
S72
G
N
A
P
A
R
G
S
G
A
G
S
R
W
S
Site 8
S76
A
R
G
S
G
A
G
S
R
W
S
G
F
K
K
Site 9
S79
S
G
A
G
S
R
W
S
G
F
K
K
R
K
Q
Site 10
S93
Q
V
L
D
R
V
F
S
S
S
Q
P
N
L
C
Site 11
S95
L
D
R
V
F
S
S
S
Q
P
N
L
C
C
S
Site 12
S102
S
Q
P
N
L
C
C
S
S
P
E
P
L
E
P
Site 13
S103
Q
P
N
L
C
C
S
S
P
E
P
L
E
P
G
Site 14
S119
A
G
R
A
E
Q
G
S
T
L
R
R
R
I
R
Site 15
T120
G
R
A
E
Q
G
S
T
L
R
R
R
I
R
E
Site 16
T146
A
S
G
A
A
G
G
T
P
P
G
G
R
S
P
Site 17
S152
G
T
P
P
G
G
R
S
P
D
S
A
P
S
S
Site 18
S155
P
G
G
R
S
P
D
S
A
P
S
S
S
S
A
Site 19
S158
R
S
P
D
S
A
P
S
S
S
S
A
S
S
S
Site 20
S159
S
P
D
S
A
P
S
S
S
S
A
S
S
S
L
Site 21
S160
P
D
S
A
P
S
S
S
S
A
S
S
S
L
S
Site 22
S161
D
S
A
P
S
S
S
S
A
S
S
S
L
S
S
Site 23
S163
A
P
S
S
S
S
A
S
S
S
L
S
S
S
P
Site 24
S164
P
S
S
S
S
A
S
S
S
L
S
S
S
P
Q
Site 25
S165
S
S
S
S
A
S
S
S
L
S
S
S
P
Q
P
Site 26
S167
S
S
A
S
S
S
L
S
S
S
P
Q
P
P
P
Site 27
S168
S
A
S
S
S
L
S
S
S
P
Q
P
P
P
R
Site 28
S169
A
S
S
S
L
S
S
S
P
Q
P
P
P
R
G
Site 29
S198
A
H
L
C
R
Q
K
S
S
S
L
P
G
T
A
Site 30
S199
H
L
C
R
Q
K
S
S
S
L
P
G
T
A
C
Site 31
S200
L
C
R
Q
K
S
S
S
L
P
G
T
A
C
L
Site 32
S223
P
P
A
E
P
A
R
S
P
A
E
S
R
A
P
Site 33
S227
P
A
R
S
P
A
E
S
R
A
P
E
T
G
E
Site 34
S238
E
T
G
E
E
H
G
S
S
Q
K
I
I
N
T
Site 35
S239
T
G
E
E
H
G
S
S
Q
K
I
I
N
T
A
Site 36
T245
S
S
Q
K
I
I
N
T
A
G
T
S
N
A
E
Site 37
T266
G
M
Y
Q
L
D
I
T
L
R
R
G
Q
S
L
Site 38
S272
I
T
L
R
R
G
Q
S
L
A
A
R
D
R
G
Site 39
T281
A
A
R
D
R
G
G
T
S
D
P
Y
V
K
F
Site 40
Y285
R
G
G
T
S
D
P
Y
V
K
F
K
I
G
G
Site 41
S298
G
G
K
E
V
F
R
S
K
I
I
H
K
N
L
Site 42
Y325
D
H
L
R
E
P
L
Y
I
K
V
F
D
Y
D
Site 43
Y331
L
Y
I
K
V
F
D
Y
D
F
G
L
Q
D
D
Site 44
T348
G
S
A
F
L
D
L
T
Q
L
E
L
N
R
P
Site 45
T356
Q
L
E
L
N
R
P
T
D
V
T
L
T
L
K
Site 46
T359
L
N
R
P
T
D
V
T
L
T
L
K
D
P
H
Site 47
T361
R
P
T
D
V
T
L
T
L
K
D
P
H
Y
P
Site 48
Y367
L
T
L
K
D
P
H
Y
P
D
H
D
L
G
I
Site 49
T392
E
G
E
S
R
D
V
T
M
L
M
R
K
S
W
Site 50
S398
V
T
M
L
M
R
K
S
W
K
R
S
S
K
E
Site 51
S402
M
R
K
S
W
K
R
S
S
K
E
L
S
E
N
Site 52
S403
R
K
S
W
K
R
S
S
K
E
L
S
E
N
E
Site 53
S407
K
R
S
S
K
E
L
S
E
N
E
V
V
G
S
Site 54
S414
S
E
N
E
V
V
G
S
Y
F
S
V
K
S
L
Site 55
T453
C
K
N
V
Q
F
Q
T
Q
S
L
R
L
S
D
Site 56
S455
N
V
Q
F
Q
T
Q
S
L
R
L
S
D
L
H
Site 57
S459
Q
T
Q
S
L
R
L
S
D
L
H
R
K
S
H
Site 58
S465
L
S
D
L
H
R
K
S
H
L
W
R
G
I
V
Site 59
S487
R
D
L
K
A
M
D
S
N
G
L
S
D
P
Y
Site 60
S491
A
M
D
S
N
G
L
S
D
P
Y
V
K
F
R
Site 61
Y494
S
N
G
L
S
D
P
Y
V
K
F
R
L
G
H
Site 62
Y504
F
R
L
G
H
Q
K
Y
K
S
K
I
M
P
K
Site 63
S506
L
G
H
Q
K
Y
K
S
K
I
M
P
K
T
L
Site 64
T512
K
S
K
I
M
P
K
T
L
N
P
Q
W
R
E
Site 65
Y526
E
Q
F
D
F
H
L
Y
E
E
R
G
G
V
I
Site 66
T536
R
G
G
V
I
D
I
T
A
W
D
K
D
A
G
Site 67
S557
G
R
C
Q
V
D
L
S
A
L
S
R
E
Q
T
Site 68
T564
S
A
L
S
R
E
Q
T
H
K
L
E
L
Q
L
Site 69
S596
T
V
S
I
S
D
L
S
V
N
S
L
E
D
Q
Site 70
S599
I
S
D
L
S
V
N
S
L
E
D
Q
K
E
R
Site 71
S614
E
E
I
L
K
R
Y
S
P
L
R
I
F
H
N
Site 72
T662
L
N
N
D
R
L
L
T
H
T
V
Y
K
N
L
Site 73
T664
N
D
R
L
L
T
H
T
V
Y
K
N
L
N
P
Site 74
Y666
R
L
L
T
H
T
V
Y
K
N
L
N
P
E
W
Site 75
T691
I
H
S
V
L
E
V
T
V
Y
D
E
D
R
D
Site 76
Y693
S
V
L
E
V
T
V
Y
D
E
D
R
D
R
S
Site 77
S700
Y
D
E
D
R
D
R
S
A
D
F
L
G
K
V
Site 78
Y722
Q
N
G
E
Q
K
A
Y
V
L
K
N
K
Q
L
Site 79
Y762
L
I
P
K
E
Q
K
Y
I
E
E
E
N
R
L
Site 80
S770
I
E
E
E
N
R
L
S
K
Q
L
L
L
R
N
Site 81
S803
N
S
C
F
D
W
D
S
P
P
R
S
L
A
A
Site 82
T852
K
D
N
R
Q
R
D
T
V
V
E
D
M
L
E
Site 83
S872
D
D
K
D
D
K
D
S
E
K
K
G
F
I
N
Site 84
S900
N
I
L
D
E
V
A
S
F
G
E
R
I
K
N
Site 85
S954
K
F
T
K
K
L
R
S
P
Y
A
I
D
N
N
Site 86
Y956
T
K
K
L
R
S
P
Y
A
I
D
N
N
E
L
Site 87
S968
N
E
L
L
D
F
L
S
R
V
P
S
D
V
Q
Site 88
S972
D
F
L
S
R
V
P
S
D
V
Q
V
V
Q
Y
Site 89
Y979
S
D
V
Q
V
V
Q
Y
Q
E
L
K
P
D
P
Site 90
S987
Q
E
L
K
P
D
P
S
H
S
P
Y
K
R
K
Site 91
S989
L
K
P
D
P
S
H
S
P
Y
K
R
K
K
N
Site 92
Y991
P
D
P
S
H
S
P
Y
K
R
K
K
N
N
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation