PhosphoNET

           
Protein Info 
   
Short Name:  DMKN
Full Name:  Dermokine
Alias:  Epidermis-specific secreted protein SK30/SK89
Type: 
Mass (Da):  47082
Number AA:  476
UniProt ID:  Q6E0U4
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S26GEAGPLQSGEESTGT
Site 2S30PLQSGEESTGTNIGE
Site 3T33SGEESTGTNIGEALG
Site 4S65EAGGAAGSKVSEALG
Site 5T81GTREAVGTGVRQVPG
Site 6S131GADAVRGSWQGVPGH
Site 7S153GGHGIFGSQGGLGGQ
Site 8T170GNPGGLGTPWVHGYP
Site 9Y176GTPWVHGYPGNSAGS
Site 10S180VHGYPGNSAGSFGMN
Site 11S183YPGNSAGSFGMNPQG
Site 12Y217GAVAQPGYGSVRASN
Site 13S219VAQPGYGSVRASNQN
Site 14S223GYGSVRASNQNEGCT
Site 15T230SNQNEGCTNPPPSGS
Site 16S235GCTNPPPSGSGGGSS
Site 17S237TNPPPSGSGGGSSNS
Site 18S241PSGSGGGSSNSGGGS
Site 19S242SGSGGGSSNSGGGSG
Site 20S244SGGGSSNSGGGSGSQ
Site 21S248SSNSGGGSGSQSGSS
Site 22S250NSGGGSGSQSGSSGS
Site 23S252GGGSGSQSGSSGSGS
Site 24S254GSGSQSGSSGSGSNG
Site 25S255SGSQSGSSGSGSNGD
Site 26S257SQSGSSGSGSNGDNN
Site 27S259SGSSGSGSNGDNNNG
Site 28S267NGDNNNGSSSGGSSS
Site 29S268GDNNNGSSSGGSSSG
Site 30S269DNNNGSSSGGSSSGS
Site 31S272NGSSSGGSSSGSSSG
Site 32S273GSSSGGSSSGSSSGG
Site 33S274SSSGGSSSGSSSGGS
Site 34S276SGGSSSGSSSGGSSG
Site 35S277GGSSSGSSSGGSSGG
Site 36S278GSSSGSSSGGSSGGS
Site 37S281SGSSSGGSSGGSSGG
Site 38S282GSSSGGSSGGSSGGS
Site 39S285SGGSSGGSSGGSSGN
Site 40S286GGSSGGSSGGSSGNS
Site 41S289SGGSSGGSSGNSGGS
Site 42S290GGSSGGSSGNSGGSR
Site 43S293SGGSSGNSGGSRGDS
Site 44S296SSGNSGGSRGDSGSE
Site 45S300SGGSRGDSGSESSWG
Site 46S302GSRGDSGSESSWGSS
Site 47S304RGDSGSESSWGSSTG
Site 48S305GDSGSESSWGSSTGS
Site 49S308GSESSWGSSTGSSSG
Site 50S309SESSWGSSTGSSSGN
Site 51T310ESSWGSSTGSSSGNH
Site 52S312SWGSSTGSSSGNHGG
Site 53S313WGSSTGSSSGNHGGS
Site 54S314GSSTGSSSGNHGGSG
Site 55S320SSGNHGGSGGGNGHK
Site 56S340PGNEARGSGESGIQN
Site 57S343EARGSGESGIQNSET
Site 58S348GESGIQNSETSPGMF
Site 59T350SGIQNSETSPGMFNF
Site 60S351GIQNSETSPGMFNFD
Site 61S385KNQVPPPSTRALLYF
Site 62Y391PSTRALLYFSRLWED
Site 63S418IIEGADASSLQKRAG
Site 64S419IEGADASSLQKRAGR
Site 65Y431AGRDDQNYNYNQHAY
Site 66Y433RDDQNYNYNQHAYPT
Site 67Y438YNYNQHAYPTAYGGK
Site 68Y446PTAYGGKYSVKTPAK
Site 69S447TAYGGKYSVKTPAKG
Site 70T450GGKYSVKTPAKGGVS
Site 71S457TPAKGGVSPSSSASR
Site 72S459AKGGVSPSSSASRVQ
Site 73S460KGGVSPSSSASRVQP
Site 74S461GGVSPSSSASRVQPG
Site 75S463VSPSSSASRVQPGLL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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