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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SFRP4
Full Name:
Secreted frizzled-related protein 4
Alias:
frizzled protein, human endometrium; FRP-4; FRPHE
Type:
Extracellular space, Extracellular region protein
Mass (Da):
39827
Number AA:
346
UniProt ID:
Q6FHJ7
International Prot ID:
IPI00017557
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0016055
GO:0030154
GO:0007566
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S99
D
P
I
K
P
C
K
S
V
C
Q
R
A
R
D
Site 2
S122
Y
N
H
S
W
P
E
S
L
A
C
D
E
L
P
Site 3
T144
I
S
P
E
A
I
V
T
D
L
P
E
D
V
K
Site 4
S174
D
V
D
C
K
R
L
S
P
D
R
C
K
C
K
Site 5
Y190
V
K
P
T
L
A
T
Y
L
S
K
N
Y
S
Y
Site 6
S192
P
T
L
A
T
Y
L
S
K
N
Y
S
Y
V
I
Site 7
Y197
Y
L
S
K
N
Y
S
Y
V
I
H
A
K
I
K
Site 8
S226
D
V
K
E
I
F
K
S
S
S
P
I
P
R
T
Site 9
S228
K
E
I
F
K
S
S
S
P
I
P
R
T
Q
V
Site 10
T233
S
S
S
P
I
P
R
T
Q
V
P
L
I
T
N
Site 11
T239
R
T
Q
V
P
L
I
T
N
S
S
C
Q
C
P
Site 12
S281
E
K
W
R
D
Q
L
S
K
R
S
I
Q
W
E
Site 13
T297
R
L
Q
E
Q
R
R
T
V
Q
D
K
K
K
T
Site 14
T304
T
V
Q
D
K
K
K
T
A
G
R
T
S
R
S
Site 15
T308
K
K
K
T
A
G
R
T
S
R
S
N
P
P
K
Site 16
S309
K
K
T
A
G
R
T
S
R
S
N
P
P
K
P
Site 17
S311
T
A
G
R
T
S
R
S
N
P
P
K
P
K
G
Site 18
S327
P
P
A
P
K
P
A
S
P
K
K
N
I
K
T
Site 19
S336
K
K
N
I
K
T
R
S
A
Q
K
R
T
N
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation