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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NADSYN1
Full Name:
Glutamine-dependent NAD(+) synthetase
Alias:
NAD(+) synthase [glutamine-hydrolyzing];NAD(+) synthetase
Type:
Mass (Da):
79285
Number AA:
706
UniProt ID:
Q6IA69
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S29
N
L
Q
R
I
L
K
S
I
E
I
A
K
N
R
Site 2
Y57
G
Y
G
C
W
D
H
Y
Y
E
S
D
T
L
L
Site 3
T62
D
H
Y
Y
E
S
D
T
L
L
H
S
F
Q
V
Site 4
T130
Y
R
E
L
R
W
F
T
P
W
S
R
S
R
H
Site 5
S133
L
R
W
F
T
P
W
S
R
S
R
H
T
E
E
Site 6
T138
P
W
S
R
S
R
H
T
E
E
Y
F
L
P
R
Site 7
Y141
R
S
R
H
T
E
E
Y
F
L
P
R
M
I
Q
Site 8
T151
P
R
M
I
Q
D
L
T
K
Q
E
T
V
P
F
Site 9
T155
Q
D
L
T
K
Q
E
T
V
P
F
G
D
A
V
Site 10
T180
E
I
C
E
E
L
W
T
P
H
S
P
H
I
D
Site 11
S183
E
E
L
W
T
P
H
S
P
H
I
D
M
G
L
Site 12
T197
L
D
G
V
E
I
I
T
N
A
S
G
S
H
Q
Site 13
T217
N
T
R
V
D
L
V
T
M
V
T
S
K
N
G
Site 14
Y241
G
C
D
G
D
R
L
Y
Y
D
G
C
A
M
I
Site 15
Y242
C
D
G
D
R
L
Y
Y
D
G
C
A
M
I
A
Site 16
S259
G
S
V
F
A
Q
G
S
Q
F
S
L
D
D
V
Site 17
S280
L
D
L
E
D
V
R
S
Y
R
A
E
I
S
S
Site 18
Y281
D
L
E
D
V
R
S
Y
R
A
E
I
S
S
R
Site 19
S286
R
S
Y
R
A
E
I
S
S
R
N
L
A
A
S
Site 20
S287
S
Y
R
A
E
I
S
S
R
N
L
A
A
S
R
Site 21
S293
S
S
R
N
L
A
A
S
R
A
S
P
Y
P
R
Site 22
S296
N
L
A
A
S
R
A
S
P
Y
P
R
V
K
V
Site 23
Y298
A
A
S
R
A
S
P
Y
P
R
V
K
V
D
F
Site 24
S318
E
D
L
L
A
P
I
S
E
P
I
E
W
K
Y
Site 25
Y325
S
E
P
I
E
W
K
Y
H
S
P
E
E
E
I
Site 26
S327
P
I
E
W
K
Y
H
S
P
E
E
E
I
S
L
Site 27
S333
H
S
P
E
E
E
I
S
L
G
P
A
C
W
L
Site 28
S347
L
W
D
F
L
R
R
S
Q
Q
A
G
F
L
L
Site 29
S382
Q
V
C
E
A
V
R
S
G
N
E
E
V
L
A
Site 30
S399
R
T
I
V
N
Q
I
S
Y
T
P
Q
D
P
R
Site 31
T401
I
V
N
Q
I
S
Y
T
P
Q
D
P
R
D
L
Site 32
Y417
G
R
I
L
T
T
C
Y
M
A
S
K
N
S
S
Site 33
S424
Y
M
A
S
K
N
S
S
Q
E
T
C
T
R
A
Site 34
T427
S
K
N
S
S
Q
E
T
C
T
R
A
R
E
L
Site 35
S440
E
L
A
Q
Q
I
G
S
H
H
I
S
L
N
I
Site 36
S521
G
S
A
N
V
D
E
S
L
L
G
Y
L
T
K
Site 37
Y525
V
D
E
S
L
L
G
Y
L
T
K
Y
D
C
S
Site 38
T527
E
S
L
L
G
Y
L
T
K
Y
D
C
S
S
A
Site 39
S532
Y
L
T
K
Y
D
C
S
S
A
D
I
N
P
I
Site 40
S533
L
T
K
Y
D
C
S
S
A
D
I
N
P
I
G
Site 41
S584
P
L
A
D
G
Q
V
S
Q
T
D
E
E
D
M
Site 42
Y595
E
E
D
M
G
M
T
Y
A
E
L
S
V
Y
G
Site 43
S599
G
M
T
Y
A
E
L
S
V
Y
G
K
L
R
K
Site 44
Y601
T
Y
A
E
L
S
V
Y
G
K
L
R
K
V
A
Site 45
T628
G
M
W
R
H
I
C
T
P
R
Q
V
A
D
K
Site 46
S641
D
K
V
K
R
F
F
S
K
Y
S
M
N
R
H
Site 47
Y643
V
K
R
F
F
S
K
Y
S
M
N
R
H
K
M
Site 48
T652
M
N
R
H
K
M
T
T
L
T
P
A
Y
H
A
Site 49
T654
R
H
K
M
T
T
L
T
P
A
Y
H
A
E
N
Site 50
Y657
M
T
T
L
T
P
A
Y
H
A
E
N
Y
S
P
Site 51
S663
A
Y
H
A
E
N
Y
S
P
E
D
N
R
F
D
Site 52
S701
L
E
R
A
E
P
Q
S
L
D
G
V
D
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation