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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OVOS1
Full Name:
Ovostatin homolog 1
Alias:
Type:
Mass (Da):
134499
Number AA:
1185
UniProt ID:
Q6IE37
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S69
A
M
V
C
Q
E
R
S
Q
N
E
T
Y
E
V
Site 2
T73
Q
E
R
S
Q
N
E
T
Y
E
V
K
M
N
N
Site 3
Y74
E
R
S
Q
N
E
T
Y
E
V
K
M
N
N
D
Site 4
T82
E
V
K
M
N
N
D
T
E
A
C
R
A
T
L
Site 5
T88
D
T
E
A
C
R
A
T
L
N
L
E
E
R
R
Site 6
S96
L
N
L
E
E
R
R
S
V
A
I
R
S
R
E
Site 7
S101
R
R
S
V
A
I
R
S
R
E
N
V
V
F
V
Site 8
T114
F
V
Q
T
D
K
P
T
Y
K
P
G
Q
K
D
Site 9
Y137
L
D
T
Y
T
F
T
Y
P
N
I
T
L
K
D
Site 10
S158
F
Q
R
Q
N
V
T
S
F
R
N
I
T
Q
L
Site 11
S166
F
R
N
I
T
Q
L
S
F
Q
L
I
S
E
P
Site 12
S171
Q
L
S
F
Q
L
I
S
E
P
M
F
G
D
Y
Site 13
Y178
S
E
P
M
F
G
D
Y
W
I
V
V
K
R
N
Site 14
S186
W
I
V
V
K
R
N
S
R
E
T
V
T
H
Q
Site 15
T189
V
K
R
N
S
R
E
T
V
T
H
Q
F
A
V
Site 16
Y199
H
Q
F
A
V
K
R
Y
V
L
P
K
F
E
V
Site 17
T213
V
T
V
N
A
P
Q
T
V
T
I
S
D
D
E
Site 18
S217
A
P
Q
T
V
T
I
S
D
D
E
F
Q
V
D
Site 19
Y246
Q
I
R
V
C
R
E
Y
F
S
S
S
N
C
E
Site 20
S249
V
C
R
E
Y
F
S
S
S
N
C
E
K
N
E
Site 21
Y311
F
E
N
M
D
T
F
Y
R
R
G
I
S
Y
F
Site 22
S316
T
F
Y
R
R
G
I
S
Y
F
G
Q
L
K
F
Site 23
Y317
F
Y
R
R
G
I
S
Y
F
G
Q
L
K
F
S
Site 24
Y348
N
D
E
F
I
G
N
Y
T
T
D
E
N
G
E
Site 25
S359
E
N
G
E
A
Q
F
S
I
D
T
S
D
I
F
Site 26
S363
A
Q
F
S
I
D
T
S
D
I
F
D
P
E
F
Site 27
Y383
H
Q
R
T
E
E
C
Y
L
P
S
W
L
T
P
Site 28
S400
L
D
A
H
F
L
V
S
R
F
Y
S
R
T
N
Site 29
Y403
H
F
L
V
S
R
F
Y
S
R
T
N
S
F
L
Site 30
S404
F
L
V
S
R
F
Y
S
R
T
N
S
F
L
K
Site 31
T406
V
S
R
F
Y
S
R
T
N
S
F
L
K
I
V
Site 32
S408
R
F
Y
S
R
T
N
S
F
L
K
I
V
P
E
Site 33
T428
C
N
Q
Q
K
V
V
T
V
H
Y
S
L
N
S
Site 34
S432
K
V
V
T
V
H
Y
S
L
N
S
E
A
Y
E
Site 35
Y438
Y
S
L
N
S
E
A
Y
E
D
D
S
N
V
K
Site 36
S442
S
E
A
Y
E
D
D
S
N
V
K
F
F
Y
L
Site 37
Y448
D
S
N
V
K
F
F
Y
L
N
G
N
F
S
F
Site 38
S484
S
G
E
I
V
A
D
S
V
R
F
Q
V
D
K
Site 39
S502
H
K
V
N
I
K
F
S
N
E
Q
G
L
P
G
Site 40
S510
N
E
Q
G
L
P
G
S
N
A
S
L
C
L
Q
Site 41
S538
R
N
V
L
L
L
K
S
E
Q
Q
L
S
A
E
Site 42
S543
L
K
S
E
Q
Q
L
S
A
E
S
V
S
S
L
Site 43
S546
E
Q
Q
L
S
A
E
S
V
S
S
L
Y
N
M
Site 44
Y562
P
S
I
E
P
Y
G
Y
F
Y
H
G
L
N
L
Site 45
Y585
I
P
Q
R
D
M
F
Y
N
G
L
Y
Y
T
P
Site 46
Y589
D
M
F
Y
N
G
L
Y
Y
T
P
V
S
N
Y
Site 47
Y590
M
F
Y
N
G
L
Y
Y
T
P
V
S
N
Y
G
Site 48
T591
F
Y
N
G
L
Y
Y
T
P
V
S
N
Y
G
D
Site 49
S594
G
L
Y
Y
T
P
V
S
N
Y
G
D
G
D
I
Site 50
Y602
N
Y
G
D
G
D
I
Y
N
I
V
R
V
R
S
Site 51
T727
L
P
G
K
V
N
I
T
V
V
A
E
S
K
Q
Site 52
S735
V
V
A
E
S
K
Q
S
S
A
C
P
N
E
G
Site 53
S736
V
A
E
S
K
Q
S
S
A
C
P
N
E
G
M
Site 54
T753
Q
K
L
N
W
K
D
T
V
V
Q
S
F
L
V
Site 55
Y802
S
D
T
Y
V
L
D
Y
L
K
S
T
E
Q
L
Site 56
S805
Y
V
L
D
Y
L
K
S
T
E
Q
L
T
E
E
Site 57
S821
Q
S
K
A
F
F
L
S
I
L
G
Y
Q
R
Q
Site 58
S830
L
G
Y
Q
R
Q
L
S
F
K
N
S
D
G
S
Site 59
S834
R
Q
L
S
F
K
N
S
D
G
S
Y
S
V
F
Site 60
S837
S
F
K
N
S
D
G
S
Y
S
V
F
W
Q
Q
Site 61
Y838
F
K
N
S
D
G
S
Y
S
V
F
W
Q
Q
S
Site 62
S839
K
N
S
D
G
S
Y
S
V
F
W
Q
Q
S
Q
Site 63
S849
W
Q
Q
S
Q
K
G
S
I
W
L
S
A
L
T
Site 64
T859
L
S
A
L
T
F
K
T
L
E
R
M
K
K
Y
Site 65
Y866
T
L
E
R
M
K
K
Y
V
F
I
D
E
N
V
Site 66
S882
K
Q
T
L
I
W
L
S
S
Q
Q
K
T
S
G
Site 67
S883
Q
T
L
I
W
L
S
S
Q
Q
K
T
S
G
C
Site 68
T887
W
L
S
S
Q
Q
K
T
S
G
C
F
K
N
D
Site 69
S888
L
S
S
Q
Q
K
T
S
G
C
F
K
N
D
G
Site 70
S915
C
L
E
A
A
L
D
S
G
V
T
N
G
Y
N
Site 71
Y921
D
S
G
V
T
N
G
Y
N
H
A
I
L
A
Y
Site 72
S941
G
K
E
K
Q
V
E
S
L
L
Q
T
L
D
Q
Site 73
T945
Q
V
E
S
L
L
Q
T
L
D
Q
S
A
P
K
Site 74
S949
L
L
Q
T
L
D
Q
S
A
P
K
L
S
K
R
Site 75
S954
D
Q
S
A
P
K
L
S
K
R
Y
Y
W
E
R
Site 76
Y958
P
K
L
S
K
R
Y
Y
W
E
R
E
R
K
P
Site 77
T967
E
R
E
R
K
P
K
T
E
E
F
P
S
F
I
Site 78
S972
P
K
T
E
E
F
P
S
F
I
P
W
A
P
S
Site 79
S979
S
F
I
P
W
A
P
S
A
Q
T
E
K
S
C
Site 80
T1001
S
R
K
I
P
D
L
T
Y
A
S
K
I
V
Q
Site 81
Y1002
R
K
I
P
D
L
T
Y
A
S
K
I
V
Q
W
Site 82
S1016
W
L
A
Q
R
M
N
S
H
G
G
F
S
S
N
Site 83
S1022
N
S
H
G
G
F
S
S
N
Q
V
I
N
V
G
Site 84
S1043
R
G
E
E
G
L
F
S
K
D
Q
N
T
V
T
Site 85
T1048
L
F
S
K
D
Q
N
T
V
T
F
S
S
E
G
Site 86
T1050
S
K
D
Q
N
T
V
T
F
S
S
E
G
S
S
Site 87
S1052
D
Q
N
T
V
T
F
S
S
E
G
S
S
E
I
Site 88
S1053
Q
N
T
V
T
F
S
S
E
G
S
S
E
I
F
Site 89
S1056
V
T
F
S
S
E
G
S
S
E
I
F
Q
V
N
Site 90
S1057
T
F
S
S
E
G
S
S
E
I
F
Q
V
N
G
Site 91
S1073
N
R
L
L
V
Q
R
S
E
V
T
Q
A
P
G
Site 92
T1076
L
V
Q
R
S
E
V
T
Q
A
P
G
E
Y
T
Site 93
T1083
T
Q
A
P
G
E
Y
T
V
D
V
E
G
H
G
Site 94
T1100
F
I
Q
I
F
R
Y
T
G
I
R
N
K
S
S
Site 95
S1106
Y
T
G
I
R
N
K
S
S
M
V
V
I
D
V
Site 96
S1107
T
G
I
R
N
K
S
S
M
V
V
I
D
V
K
Site 97
S1124
S
G
F
T
P
T
M
S
S
I
E
E
V
N
N
Site 98
S1125
G
F
T
P
T
M
S
S
I
E
E
V
N
N
R
Site 99
Y1142
I
F
Q
H
K
D
S
Y
I
E
Y
K
R
A
D
Site 100
Y1145
H
K
D
S
Y
I
E
Y
K
R
A
D
S
F
P
Site 101
S1150
I
E
Y
K
R
A
D
S
F
P
F
S
V
E
Q
Site 102
S1154
R
A
D
S
F
P
F
S
V
E
Q
S
N
L
V
Site 103
Y1172
Q
P
A
P
A
M
V
Y
D
Y
Y
E
K
G
R
Site 104
Y1174
A
P
A
M
V
Y
D
Y
Y
E
K
G
R
Q
A
Site 105
Y1175
P
A
M
V
Y
D
Y
Y
E
K
G
R
Q
A
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation