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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IQCE
Full Name:
IQ domain-containing protein E
Alias:
IQ motif containing E; KIAA1023
Type:
Unknown function
Mass (Da):
77298
Number AA:
695
UniProt ID:
Q6IPM2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
T
G
E
P
A
L
D
T
G
D
D
S
L
S
A
Site 2
S16
A
L
D
T
G
D
D
S
L
S
A
V
T
F
D
Site 3
S18
D
T
G
D
D
S
L
S
A
V
T
F
D
S
D
Site 4
S24
L
S
A
V
T
F
D
S
D
V
E
T
K
A
K
Site 5
T28
T
F
D
S
D
V
E
T
K
A
K
R
K
A
F
Site 6
T41
A
F
H
K
P
P
P
T
S
P
K
S
P
Y
L
Site 7
S42
F
H
K
P
P
P
T
S
P
K
S
P
Y
L
S
Site 8
S45
P
P
P
T
S
P
K
S
P
Y
L
S
K
P
R
Site 9
Y47
P
T
S
P
K
S
P
Y
L
S
K
P
R
K
V
Site 10
S49
S
P
K
S
P
Y
L
S
K
P
R
K
V
A
S
Site 11
S56
S
K
P
R
K
V
A
S
W
R
S
L
R
T
A
Site 12
S59
R
K
V
A
S
W
R
S
L
R
T
A
G
S
M
Site 13
S65
R
S
L
R
T
A
G
S
M
P
L
G
G
R
A
Site 14
S73
M
P
L
G
G
R
A
S
L
T
P
Q
K
L
W
Site 15
T75
L
G
G
R
A
S
L
T
P
Q
K
L
W
L
G
Site 16
T83
P
Q
K
L
W
L
G
T
A
K
P
G
S
L
T
Site 17
S88
L
G
T
A
K
P
G
S
L
T
Q
A
L
N
S
Site 18
T90
T
A
K
P
G
S
L
T
Q
A
L
N
S
P
L
Site 19
S95
S
L
T
Q
A
L
N
S
P
L
T
W
E
H
A
Site 20
T98
Q
A
L
N
S
P
L
T
W
E
H
A
W
T
G
Site 21
T104
L
T
W
E
H
A
W
T
G
V
P
G
G
T
P
Site 22
T110
W
T
G
V
P
G
G
T
P
D
C
L
T
D
T
Site 23
T115
G
G
T
P
D
C
L
T
D
T
F
R
V
K
R
Site 24
T117
T
P
D
C
L
T
D
T
F
R
V
K
R
P
H
Site 25
S128
K
R
P
H
L
R
R
S
A
S
N
G
H
V
P
Site 26
S130
P
H
L
R
R
S
A
S
N
G
H
V
P
G
T
Site 27
T137
S
N
G
H
V
P
G
T
P
V
Y
R
E
K
E
Site 28
Y140
H
V
P
G
T
P
V
Y
R
E
K
E
D
M
Y
Site 29
Y147
Y
R
E
K
E
D
M
Y
D
E
I
I
E
L
K
Site 30
S156
E
I
I
E
L
K
K
S
L
H
V
Q
K
S
D
Site 31
S162
K
S
L
H
V
Q
K
S
D
V
D
L
M
R
T
Site 32
S179
R
R
L
E
E
E
N
S
R
K
D
R
Q
I
E
Site 33
T195
L
L
D
P
S
R
G
T
D
F
V
R
T
L
A
Site 34
T200
R
G
T
D
F
V
R
T
L
A
E
K
R
P
D
Site 35
S209
A
E
K
R
P
D
A
S
W
V
I
N
G
L
K
Site 36
T232
Q
C
K
E
K
D
G
T
I
S
K
L
Q
T
D
Site 37
T238
G
T
I
S
K
L
Q
T
D
M
K
T
T
N
L
Site 38
T242
K
L
Q
T
D
M
K
T
T
N
L
E
E
M
R
Site 39
Y256
R
I
A
M
E
T
Y
Y
E
E
V
H
R
L
Q
Site 40
T264
E
E
V
H
R
L
Q
T
L
L
A
S
S
E
T
Site 41
T282
K
P
L
G
E
K
K
T
G
A
K
R
Q
K
K
Site 42
S292
K
R
Q
K
K
M
G
S
A
L
L
S
L
S
R
Site 43
S296
K
M
G
S
A
L
L
S
L
S
R
S
V
Q
E
Site 44
S298
G
S
A
L
L
S
L
S
R
S
V
Q
E
L
T
Site 45
S300
A
L
L
S
L
S
R
S
V
Q
E
L
T
E
E
Site 46
T305
S
R
S
V
Q
E
L
T
E
E
N
Q
S
L
K
Site 47
S310
E
L
T
E
E
N
Q
S
L
K
E
D
L
D
R
Site 48
S320
E
D
L
D
R
V
L
S
T
S
P
T
I
S
K
Site 49
S322
L
D
R
V
L
S
T
S
P
T
I
S
K
T
Q
Site 50
T324
R
V
L
S
T
S
P
T
I
S
K
T
Q
G
Y
Site 51
S326
L
S
T
S
P
T
I
S
K
T
Q
G
Y
V
E
Site 52
T328
T
S
P
T
I
S
K
T
Q
G
Y
V
E
W
S
Site 53
Y331
T
I
S
K
T
Q
G
Y
V
E
W
S
K
P
R
Site 54
S335
T
Q
G
Y
V
E
W
S
K
P
R
L
L
R
R
Site 55
S351
V
E
L
E
K
K
L
S
V
M
E
S
S
K
S
Site 56
S355
K
K
L
S
V
M
E
S
S
K
S
H
A
A
E
Site 57
S358
S
V
M
E
S
S
K
S
H
A
A
E
P
V
R
Site 58
S366
H
A
A
E
P
V
R
S
H
P
P
A
C
L
A
Site 59
S374
H
P
P
A
C
L
A
S
S
S
A
L
H
R
Q
Site 60
S376
P
A
C
L
A
S
S
S
A
L
H
R
Q
P
R
Site 61
T455
V
L
R
E
E
I
Q
T
L
T
S
K
L
Q
E
Site 62
T488
A
Q
E
L
P
A
P
T
P
S
S
R
H
C
E
Site 63
S490
E
L
P
A
P
T
P
S
S
R
H
C
E
Q
D
Site 64
S491
L
P
A
P
T
P
S
S
R
H
C
E
Q
D
W
Site 65
S502
E
Q
D
W
P
P
D
S
S
E
E
G
L
P
R
Site 66
S503
Q
D
W
P
P
D
S
S
E
E
G
L
P
R
P
Site 67
S512
E
G
L
P
R
P
R
S
P
C
S
D
G
R
R
Site 68
S515
P
R
P
R
S
P
C
S
D
G
R
R
D
A
A
Site 69
T558
A
A
F
R
G
H
L
T
R
T
K
L
L
A
S
Site 70
S565
T
R
T
K
L
L
A
S
K
A
H
G
S
E
P
Site 71
S570
L
A
S
K
A
H
G
S
E
P
P
S
V
P
G
Site 72
S574
A
H
G
S
E
P
P
S
V
P
G
L
P
D
Q
Site 73
S582
V
P
G
L
P
D
Q
S
S
P
V
P
R
V
P
Site 74
S583
P
G
L
P
D
Q
S
S
P
V
P
R
V
P
S
Site 75
S590
S
P
V
P
R
V
P
S
P
I
A
Q
A
T
G
Site 76
T596
P
S
P
I
A
Q
A
T
G
S
P
V
Q
E
E
Site 77
S598
P
I
A
Q
A
T
G
S
P
V
Q
E
E
A
I
Site 78
S622
H
L
A
R
A
R
H
S
A
T
G
K
R
T
T
Site 79
T629
S
A
T
G
K
R
T
T
T
A
A
S
T
R
R
Site 80
T630
A
T
G
K
R
T
T
T
A
A
S
T
R
R
R
Site 81
S633
K
R
T
T
T
A
A
S
T
R
R
R
S
A
S
Site 82
T634
R
T
T
T
A
A
S
T
R
R
R
S
A
S
A
Site 83
S638
A
A
S
T
R
R
R
S
A
S
A
T
H
G
D
Site 84
S640
S
T
R
R
R
S
A
S
A
T
H
G
D
A
S
Site 85
T642
R
R
R
S
A
S
A
T
H
G
D
A
S
S
P
Site 86
S647
S
A
T
H
G
D
A
S
S
P
P
F
L
A
A
Site 87
S648
A
T
H
G
D
A
S
S
P
P
F
L
A
A
L
Site 88
S659
L
A
A
L
P
D
P
S
P
S
G
P
Q
A
L
Site 89
S661
A
L
P
D
P
S
P
S
G
P
Q
A
L
A
P
Site 90
S676
L
P
G
D
D
V
N
S
D
D
S
D
D
I
V
Site 91
S679
D
D
V
N
S
D
D
S
D
D
I
V
I
A
P
Site 92
S687
D
D
I
V
I
A
P
S
L
P
T
K
N
F
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation