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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NAPEPLD
Full Name:
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D
Alias:
Type:
Mass (Da):
45596
Number AA:
393
UniProt ID:
Q6IQ20
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
D
E
N
E
S
N
Q
S
L
M
T
S
S
Q
Y
Site 2
S13
S
N
Q
S
L
M
T
S
S
Q
Y
P
K
E
A
Site 3
S14
N
Q
S
L
M
T
S
S
Q
Y
P
K
E
A
V
Site 4
Y16
S
L
M
T
S
S
Q
Y
P
K
E
A
V
R
K
Site 5
S27
A
V
R
K
R
Q
N
S
A
R
N
S
G
A
S
Site 6
S31
R
Q
N
S
A
R
N
S
G
A
S
D
S
S
R
Site 7
S34
S
A
R
N
S
G
A
S
D
S
S
R
F
S
R
Site 8
S36
R
N
S
G
A
S
D
S
S
R
F
S
R
K
S
Site 9
S37
N
S
G
A
S
D
S
S
R
F
S
R
K
S
F
Site 10
S40
A
S
D
S
S
R
F
S
R
K
S
F
K
L
D
Site 11
S43
S
S
R
F
S
R
K
S
F
K
L
D
Y
R
L
Site 12
Y48
R
K
S
F
K
L
D
Y
R
L
E
E
D
V
T
Site 13
T55
Y
R
L
E
E
D
V
T
K
S
K
K
G
K
D
Site 14
S57
L
E
E
D
V
T
K
S
K
K
G
K
D
G
R
Site 15
S91
L
I
M
E
K
D
H
S
S
V
P
S
S
K
E
Site 16
S92
I
M
E
K
D
H
S
S
V
P
S
S
K
E
E
Site 17
S95
K
D
H
S
S
V
P
S
S
K
E
E
L
D
K
Site 18
S96
D
H
S
S
V
P
S
S
K
E
E
L
D
K
E
Site 19
Y110
E
L
P
V
L
K
P
Y
F
I
T
N
P
E
E
Site 20
S151
F
L
T
D
P
I
F
S
S
R
A
S
P
S
Q
Site 21
S152
L
T
D
P
I
F
S
S
R
A
S
P
S
Q
Y
Site 22
S155
P
I
F
S
S
R
A
S
P
S
Q
Y
M
G
P
Site 23
S157
F
S
S
R
A
S
P
S
Q
Y
M
G
P
K
R
Site 24
Y159
S
R
A
S
P
S
Q
Y
M
G
P
K
R
F
R
Site 25
S168
G
P
K
R
F
R
R
S
P
C
T
I
S
E
L
Site 26
T171
R
F
R
R
S
P
C
T
I
S
E
L
P
P
I
Site 27
S173
R
R
S
P
C
T
I
S
E
L
P
P
I
D
A
Site 28
Y188
V
L
I
S
H
N
H
Y
D
H
L
D
Y
N
S
Site 29
Y193
N
H
Y
D
H
L
D
Y
N
S
V
I
A
L
N
Site 30
S195
Y
D
H
L
D
Y
N
S
V
I
A
L
N
E
R
Site 31
T245
V
P
G
H
D
K
V
T
F
V
F
T
P
S
Q
Site 32
Y319
E
P
R
W
F
M
K
Y
Q
H
V
D
P
E
E
Site 33
T332
E
E
A
V
R
I
H
T
D
V
Q
T
K
K
S
Site 34
Y354
F
A
L
A
N
E
H
Y
L
E
P
P
V
K
L
Site 35
Y385
L
K
H
G
E
S
R
Y
L
N
N
D
D
E
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation