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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANO7
Full Name:
Anoctamin-7
Alias:
Dresden transmembrane protein of the prostate;IPCA-5;New gene expressed in prostate;Prostate cancer-associated protein 5;Transmembrane protein 16G
Type:
Mass (Da):
105531
Number AA:
933
UniProt ID:
Q6IWH7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y28
P
A
V
R
T
G
L
Y
C
R
D
Q
A
H
A
Site 2
T41
H
A
E
R
W
A
M
T
S
E
T
S
S
G
S
Site 3
S42
A
E
R
W
A
M
T
S
E
T
S
S
G
S
H
Site 4
T44
R
W
A
M
T
S
E
T
S
S
G
S
H
C
A
Site 5
S46
A
M
T
S
E
T
S
S
G
S
H
C
A
R
S
Site 6
S48
T
S
E
T
S
S
G
S
H
C
A
R
S
R
M
Site 7
T66
R
A
Q
E
E
D
S
T
V
L
I
D
V
S
P
Site 8
S72
S
T
V
L
I
D
V
S
P
P
E
A
E
K
R
Site 9
S81
P
E
A
E
K
R
G
S
Y
G
S
T
A
H
A
Site 10
Y82
E
A
E
K
R
G
S
Y
G
S
T
A
H
A
S
Site 11
S84
E
K
R
G
S
Y
G
S
T
A
H
A
S
E
P
Site 12
T85
K
R
G
S
Y
G
S
T
A
H
A
S
E
P
G
Site 13
S89
Y
G
S
T
A
H
A
S
E
P
G
G
Q
Q
A
Site 14
S103
A
A
A
C
R
A
G
S
P
A
K
P
R
I
A
Site 15
S128
K
L
D
R
Q
Q
D
S
A
A
R
D
R
T
D
Site 16
T134
D
S
A
A
R
D
R
T
D
M
H
R
T
W
R
Site 17
T166
D
V
Q
D
G
N
T
T
V
H
Y
A
L
L
S
Site 18
Y169
D
G
N
T
T
V
H
Y
A
L
L
S
A
S
W
Site 19
S200
Q
E
L
P
N
Q
A
S
N
W
S
A
G
L
L
Site 20
Y227
V
P
D
V
P
P
E
Y
Y
S
C
R
F
R
V
Site 21
Y228
P
D
V
P
P
E
Y
Y
S
C
R
F
R
V
N
Site 22
S243
K
L
P
R
F
L
G
S
D
N
Q
D
T
F
F
Site 23
T248
L
G
S
D
N
Q
D
T
F
F
T
S
T
K
R
Site 24
T253
Q
D
T
F
F
T
S
T
K
R
H
Q
I
L
F
Site 25
T266
L
F
E
I
L
A
K
T
P
Y
G
H
E
K
K
Site 26
T300
L
H
D
G
P
F
K
T
P
P
E
G
P
Q
A
Site 27
Y329
R
W
G
K
W
N
K
Y
Q
P
L
D
H
V
R
Site 28
Y338
P
L
D
H
V
R
R
Y
F
G
E
K
V
A
L
Site 29
S387
P
T
Q
E
L
C
G
S
K
D
S
F
E
M
C
Site 30
S390
E
L
C
G
S
K
D
S
F
E
M
C
P
L
C
Site 31
Y457
Y
R
W
D
C
S
D
Y
E
D
T
E
E
R
P
Site 32
T460
D
C
S
D
Y
E
D
T
E
E
R
P
R
P
Q
Site 33
S471
P
R
P
Q
F
A
A
S
A
P
M
T
A
P
N
Site 34
T481
M
T
A
P
N
P
I
T
G
E
D
E
P
Y
F
Site 35
Y487
I
T
G
E
D
E
P
Y
F
P
E
R
S
R
A
Site 36
S492
E
P
Y
F
P
E
R
S
R
A
R
R
M
L
A
Site 37
S546
A
W
A
S
R
I
A
S
L
T
G
S
V
V
N
Site 38
T579
T
R
W
E
M
H
R
T
Q
T
K
F
E
D
A
Site 39
Y605
N
F
Y
S
S
P
V
Y
I
A
F
F
K
G
R
Site 40
Y616
F
K
G
R
F
V
G
Y
P
G
N
Y
H
T
L
Site 41
Y620
F
V
G
Y
P
G
N
Y
H
T
L
F
G
V
R
Site 42
S676
W
Q
K
F
R
L
R
S
K
K
R
K
A
G
A
Site 43
S684
K
K
R
K
A
G
A
S
A
G
A
S
Q
G
P
Site 44
S688
A
G
A
S
A
G
A
S
Q
G
P
W
E
D
D
Site 45
Y696
Q
G
P
W
E
D
D
Y
E
L
V
P
C
E
G
Site 46
Y751
A
R
K
F
V
C
E
Y
R
R
P
V
A
E
R
Site 47
Y795
S
D
F
L
P
R
A
Y
Y
R
W
T
R
A
H
Site 48
Y796
D
F
L
P
R
A
Y
Y
R
W
T
R
A
H
D
Site 49
S818
T
L
A
R
A
P
S
S
F
A
A
A
H
N
R
Site 50
Y839
F
R
D
D
D
G
H
Y
S
Q
T
Y
W
N
L
Site 51
Y843
D
G
H
Y
S
Q
T
Y
W
N
L
L
A
I
R
Site 52
S878
L
V
P
D
I
P
E
S
V
E
I
K
V
K
R
Site 53
Y887
E
I
K
V
K
R
E
Y
Y
L
A
K
Q
A
L
Site 54
Y888
I
K
V
K
R
E
Y
Y
L
A
K
Q
A
L
A
Site 55
S914
K
D
E
Q
P
K
G
S
E
L
S
S
H
W
T
Site 56
S918
P
K
G
S
E
L
S
S
H
W
T
P
F
T
V
Site 57
T921
S
E
L
S
S
H
W
T
P
F
T
V
P
K
A
Site 58
T924
S
S
H
W
T
P
F
T
V
P
K
A
S
Q
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation