KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CapZIP
Full Name:
CapZ-interacting protein
Alias:
MGC21854; MK2S4; Protein kinase substrate CapZIP; RCSD domain containing 1; RCSD1; RP3-503M14.1
Type:
Cytoskeletal protein
Mass (Da):
44504
Number AA:
416
UniProt ID:
Q6JBY9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0016301
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
T
N
A
N
V
D
N
S
A
S
P
S
V
A
Q
Site 2
S17
A
N
V
D
N
S
A
S
P
S
V
A
Q
L
A
Site 3
S19
V
D
N
S
A
S
P
S
V
A
Q
L
A
G
R
Site 4
T37
Q
A
A
A
A
K
E
T
P
A
S
K
P
T
R
Site 5
S40
A
A
K
E
T
P
A
S
K
P
T
R
R
K
P
Site 6
T43
E
T
P
A
S
K
P
T
R
R
K
P
P
C
S
Site 7
S50
T
R
R
K
P
P
C
S
L
P
L
F
P
P
K
Site 8
S68
G
Q
N
G
E
E
K
S
P
P
N
A
S
H
P
Site 9
S73
E
K
S
P
P
N
A
S
H
P
P
K
F
K
V
Site 10
S82
P
P
K
F
K
V
K
S
S
P
L
I
E
K
L
Site 11
S83
P
K
F
K
V
K
S
S
P
L
I
E
K
L
Q
Site 12
T94
E
K
L
Q
A
N
L
T
F
D
P
A
A
L
L
Site 13
S105
A
A
L
L
P
G
A
S
P
K
S
P
G
L
K
Site 14
S108
L
P
G
A
S
P
K
S
P
G
L
K
A
M
V
Site 15
S116
P
G
L
K
A
M
V
S
P
F
H
S
P
P
S
Site 16
S120
A
M
V
S
P
F
H
S
P
P
S
T
P
S
S
Site 17
S123
S
P
F
H
S
P
P
S
T
P
S
S
P
G
V
Site 18
T124
P
F
H
S
P
P
S
T
P
S
S
P
G
V
R
Site 19
S126
H
S
P
P
S
T
P
S
S
P
G
V
R
S
R
Site 20
S127
S
P
P
S
T
P
S
S
P
G
V
R
S
R
P
Site 21
S132
P
S
S
P
G
V
R
S
R
P
S
E
A
E
E
Site 22
S135
P
G
V
R
S
R
P
S
E
A
E
E
V
P
V
Site 23
S143
E
A
E
E
V
P
V
S
F
D
Q
P
P
E
G
Site 24
S151
F
D
Q
P
P
E
G
S
H
L
P
C
Y
N
K
Site 25
Y156
E
G
S
H
L
P
C
Y
N
K
V
R
T
R
G
Site 26
S164
N
K
V
R
T
R
G
S
I
K
R
R
P
P
S
Site 27
S171
S
I
K
R
R
P
P
S
R
R
F
R
R
S
Q
Site 28
S177
P
S
R
R
F
R
R
S
Q
S
D
C
G
E
L
Site 29
S179
R
R
F
R
R
S
Q
S
D
C
G
E
L
G
D
Site 30
S193
D
F
R
A
V
E
S
S
Q
Q
N
G
A
K
E
Site 31
S209
D
G
D
E
V
L
P
S
K
S
K
A
P
G
S
Site 32
S211
D
E
V
L
P
S
K
S
K
A
P
G
S
P
L
Site 33
S216
S
K
S
K
A
P
G
S
P
L
S
S
E
G
A
Site 34
S219
K
A
P
G
S
P
L
S
S
E
G
A
A
G
E
Site 35
S220
A
P
G
S
P
L
S
S
E
G
A
A
G
E
G
Site 36
T230
A
A
G
E
G
V
R
T
L
G
P
A
E
K
P
Site 37
S242
E
K
P
P
L
R
R
S
P
S
R
T
E
K
Q
Site 38
S244
P
P
L
R
R
S
P
S
R
T
E
K
Q
E
E
Site 39
T246
L
R
R
S
P
S
R
T
E
K
Q
E
E
D
R
Site 40
T255
K
Q
E
E
D
R
A
T
E
E
A
K
N
G
E
Site 41
S267
N
G
E
K
A
R
R
S
S
E
E
V
D
G
Q
Site 42
S268
G
E
K
A
R
R
S
S
E
E
V
D
G
Q
H
Site 43
S284
A
Q
E
E
V
P
E
S
P
Q
T
S
G
P
E
Site 44
T287
E
V
P
E
S
P
Q
T
S
G
P
E
A
E
N
Site 45
S288
V
P
E
S
P
Q
T
S
G
P
E
A
E
N
R
Site 46
S298
E
A
E
N
R
C
G
S
P
R
E
E
K
P
A
Site 47
S333
E
V
G
P
E
H
D
S
Q
E
T
K
K
L
E
Site 48
T348
E
G
A
A
V
K
E
T
P
H
S
P
P
G
G
Site 49
S351
A
V
K
E
T
P
H
S
P
P
G
G
V
K
G
Site 50
S382
A
V
L
E
P
G
C
S
P
Q
T
G
P
A
Q
Site 51
S394
P
A
Q
L
E
T
S
S
E
V
Q
S
E
P
A
Site 52
S398
E
T
S
S
E
V
Q
S
E
P
A
V
P
K
P
Site 53
T409
V
P
K
P
E
D
D
T
P
V
Q
D
T
K
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation