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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC25A25
Full Name:
Calcium-binding mitochondrial carrier protein SCaMC-2
Alias:
APC3; KIAA1896; MCSC3; Mitochondrial ATP-Mg/Pi carrier protein 3; Pcscl; Scamc2; Scmc2; Slc25a25; Small calcium-binding mitochondrial carrier protein 2; Solute carrier family 25 member 25
Type:
Mitochondrial solute carrier protein
Mass (Da):
52663
Number AA:
469
UniProt ID:
Q6KCM7
International Prot ID:
IPI00173346
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005743
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
L
C
L
C
L
Y
V
P
V
I
G
E
A
Site 2
Y20
E
A
Q
T
E
F
Q
Y
F
E
S
K
G
L
P
Site 3
S42
K
L
S
V
F
I
P
S
Q
E
F
S
T
Y
R
Site 4
Y48
P
S
Q
E
F
S
T
Y
R
Q
W
K
Q
K
I
Site 5
Y75
D
F
E
E
F
V
H
Y
L
Q
D
H
E
K
K
Site 6
S89
K
L
R
L
V
F
K
S
L
D
K
K
N
D
G
Site 7
S106
D
A
Q
E
I
M
Q
S
L
R
D
L
G
V
K
Site 8
S115
R
D
L
G
V
K
I
S
E
Q
Q
A
E
K
I
Site 9
S125
Q
A
E
K
I
L
K
S
M
D
K
N
G
T
M
Site 10
Y142
D
W
N
E
W
R
D
Y
H
L
L
H
P
V
E
Site 11
T177
L
T
V
P
D
E
F
T
V
E
E
R
Q
T
G
Site 12
T204
G
A
V
S
R
T
C
T
A
P
L
D
R
L
K
Site 13
S241
I
R
E
G
G
A
R
S
L
W
R
G
N
G
I
Site 14
S257
V
L
K
I
A
P
E
S
A
I
K
F
M
A
Y
Site 15
Y264
S
A
I
K
F
M
A
Y
E
Q
I
K
R
L
V
Site 16
S273
Q
I
K
R
L
V
G
S
D
Q
E
T
L
R
I
Site 17
T277
L
V
G
S
D
Q
E
T
L
R
I
H
E
R
L
Site 18
T306
Y
P
M
E
V
L
K
T
R
M
A
L
R
K
T
Site 19
T313
T
R
M
A
L
R
K
T
G
Q
Y
S
G
M
L
Site 20
Y316
A
L
R
K
T
G
Q
Y
S
G
M
L
D
C
A
Site 21
S317
L
R
K
T
G
Q
Y
S
G
M
L
D
C
A
R
Site 22
Y336
R
E
G
V
A
A
F
Y
K
G
Y
V
P
N
M
Site 23
Y368
K
N
A
W
L
Q
H
Y
A
V
N
S
A
D
P
Site 24
S410
T
R
M
Q
A
Q
A
S
I
E
G
A
P
E
V
Site 25
S420
G
A
P
E
V
T
M
S
S
L
F
K
H
I
L
Site 26
T429
L
F
K
H
I
L
R
T
E
G
A
F
G
L
Y
Site 27
Y436
T
E
G
A
F
G
L
Y
R
G
L
A
P
N
F
Site 28
T463
V
Y
E
N
L
K
I
T
L
G
V
Q
S
R
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation