PhosphoNET

           
Protein Info 
   
Short Name:  GDF6
Full Name:  Growth/differentiation factor 6
Alias:  Growth/differentiation factor 16
Type: 
Mass (Da):  50662
Number AA:  455
UniProt ID:  Q6KF10
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S27LPGFQQASISSSSSS
Site 2S29GFQQASISSSSSSAE
Site 3S30FQQASISSSSSSAEL
Site 4S31QQASISSSSSSAELG
Site 5S32QASISSSSSSAELGS
Site 6S33ASISSSSSSAELGST
Site 7S34SISSSSSSAELGSTK
Site 8S39SSSAELGSTKGMRSR
Site 9T40SSAELGSTKGMRSRK
Site 10S58MQRAPRDSDAGREGQ
Site 11Y102HEYMLSIYRTYSIAE
Site 12S116EKLGINASFFQSSKS
Site 13S120INASFFQSSKSANTI
Site 14S123SFFQSSKSANTITSF
Site 15S129KSANTITSFVDRGLD
Site 16S139DRGLDDLSHTPLRRQ
Site 17T141GLDDLSHTPLRRQKY
Site 18Y148TPLRRQKYLFDVSML
Site 19S153QKYLFDVSMLSDKEE
Site 20S174RLFRQAPSAPWGPPA
Site 21T201PLLLDARTLDPQGAP
Site 22S262PPPPDLRSLGFGRRV
Site 23S299EMREQLGSAEAAGPG
Site 24S312PGAGAEGSWPPPSGA
Site 25S317EGSWPPPSGAPDARP
Site 26S328DARPWLPSPGRRRRR
Site 27T336PGRRRRRTAFASRHG
Site 28S340RRRTAFASRHGKRHG
Site 29S350GKRHGKKSRLRCSKK
Site 30S355KKSRLRCSKKPLHVN
Site 31Y381APLEYEAYHCEGVCD
Site 32S393VCDFPLRSHLEPTNH
Site 33T405TNHAIIQTLMNSMDP
Site 34S409IIQTLMNSMDPGSTP
Site 35S414MNSMDPGSTPPSCCV
Site 36T415NSMDPGSTPPSCCVP
Site 37S418DPGSTPPSCCVPTKL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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