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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LIN54
Full Name:
Protein lin-54 homolog
Alias:
CXC domain-containing protein 1
Type:
Uncharacterized
Mass (Da):
79423
Number AA:
749
UniProt ID:
Q6MZP7
International Prot ID:
IPI00789941
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005694
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S52
E
E
I
V
N
I
N
S
T
G
D
S
T
A
T
Site 2
S56
N
I
N
S
T
G
D
S
T
A
T
P
I
S
T
Site 3
T57
I
N
S
T
G
D
S
T
A
T
P
I
S
T
E
Site 4
T59
S
T
G
D
S
T
A
T
P
I
S
T
E
P
I
Site 5
S62
D
S
T
A
T
P
I
S
T
E
P
I
T
V
Y
Site 6
T67
P
I
S
T
E
P
I
T
V
Y
S
N
H
T
N
Site 7
Y69
S
T
E
P
I
T
V
Y
S
N
H
T
N
Q
V
Site 8
T90
T
K
A
D
S
N
T
T
V
K
P
A
F
P
S
Site 9
T106
L
Q
K
L
G
A
Q
T
P
V
T
I
S
A
N
Site 10
S121
Q
I
I
L
N
K
V
S
Q
T
S
D
L
K
L
Site 11
T132
D
L
K
L
G
N
Q
T
L
K
P
D
G
Q
K
Site 12
T143
D
G
Q
K
L
I
L
T
T
L
G
K
S
G
S
Site 13
T144
G
Q
K
L
I
L
T
T
L
G
K
S
G
S
P
Site 14
S148
I
L
T
T
L
G
K
S
G
S
P
I
V
L
A
Site 15
S150
T
T
L
G
K
S
G
S
P
I
V
L
A
L
P
Site 16
T212
P
G
S
Q
L
I
N
T
T
T
Q
P
S
V
L
Site 17
T213
G
S
Q
L
I
N
T
T
T
Q
P
S
V
L
Q
Site 18
T214
S
Q
L
I
N
T
T
T
Q
P
S
V
L
Q
T
Site 19
T221
T
Q
P
S
V
L
Q
T
Q
Q
L
K
T
V
Q
Site 20
T226
L
Q
T
Q
Q
L
K
T
V
Q
I
A
K
K
P
Site 21
T235
Q
I
A
K
K
P
R
T
P
T
S
G
P
V
I
Site 22
T237
A
K
K
P
R
T
P
T
S
G
P
V
I
T
K
Site 23
S238
K
K
P
R
T
P
T
S
G
P
V
I
T
K
L
Site 24
S253
I
F
A
K
P
I
N
S
K
A
V
T
G
Q
T
Site 25
T260
S
K
A
V
T
G
Q
T
T
Q
V
S
P
P
V
Site 26
S264
T
G
Q
T
T
Q
V
S
P
P
V
I
A
G
R
Site 27
S274
V
I
A
G
R
V
L
S
Q
S
T
P
G
T
P
Site 28
S276
A
G
R
V
L
S
Q
S
T
P
G
T
P
S
K
Site 29
T277
G
R
V
L
S
Q
S
T
P
G
T
P
S
K
T
Site 30
T280
L
S
Q
S
T
P
G
T
P
S
K
T
I
T
I
Site 31
S282
Q
S
T
P
G
T
P
S
K
T
I
T
I
S
E
Site 32
T284
T
P
G
T
P
S
K
T
I
T
I
S
E
S
G
Site 33
S288
P
S
K
T
I
T
I
S
E
S
G
V
I
G
S
Site 34
S295
S
E
S
G
V
I
G
S
T
L
N
S
T
T
Q
Site 35
T296
E
S
G
V
I
G
S
T
L
N
S
T
T
Q
T
Site 36
S299
V
I
G
S
T
L
N
S
T
T
Q
T
P
N
K
Site 37
T303
T
L
N
S
T
T
Q
T
P
N
K
I
A
I
S
Site 38
S310
T
P
N
K
I
A
I
S
P
L
K
S
P
N
K
Site 39
S314
I
A
I
S
P
L
K
S
P
N
K
A
V
K
S
Site 40
S321
S
P
N
K
A
V
K
S
T
V
Q
T
I
T
V
Site 41
S356
Q
Q
I
Q
V
P
G
S
K
F
H
Y
V
R
L
Site 42
T367
Y
V
R
L
V
T
A
T
S
A
S
S
S
T
Q
Site 43
S368
V
R
L
V
T
A
T
S
A
S
S
S
T
Q
P
Site 44
S372
T
A
T
S
A
S
S
S
T
Q
P
V
S
Q
N
Site 45
T373
A
T
S
A
S
S
S
T
Q
P
V
S
Q
N
P
Site 46
S377
S
S
S
T
Q
P
V
S
Q
N
P
S
T
N
T
Site 47
S381
Q
P
V
S
Q
N
P
S
T
N
T
Q
P
L
Q
Site 48
T382
P
V
S
Q
N
P
S
T
N
T
Q
P
L
Q
Q
Site 49
S424
P
K
P
I
N
P
T
S
Q
I
V
T
T
S
Q
Site 50
T428
N
P
T
S
Q
I
V
T
T
S
Q
P
Q
Q
R
Site 51
S430
T
S
Q
I
V
T
T
S
Q
P
Q
Q
R
L
I
Site 52
T441
Q
R
L
I
M
P
A
T
P
L
P
Q
I
Q
P
Site 53
T451
P
Q
I
Q
P
N
L
T
N
L
P
P
G
T
V
Site 54
Y477
Y
A
V
L
P
A
Q
Y
V
T
Q
L
Q
Q
S
Site 55
S484
Y
V
T
Q
L
Q
Q
S
S
Y
V
S
I
A
S
Site 56
S485
V
T
Q
L
Q
Q
S
S
Y
V
S
I
A
S
N
Site 57
Y486
T
Q
L
Q
Q
S
S
Y
V
S
I
A
S
N
S
Site 58
S488
L
Q
Q
S
S
Y
V
S
I
A
S
N
S
T
F
Site 59
S491
S
S
Y
V
S
I
A
S
N
S
T
F
T
G
T
Site 60
S493
Y
V
S
I
A
S
N
S
T
F
T
G
T
S
G
Site 61
T503
T
G
T
S
G
I
Q
T
Q
A
R
L
P
F
N
Site 62
S515
P
F
N
G
I
I
P
S
E
S
A
S
R
P
R
Site 63
S519
I
I
P
S
E
S
A
S
R
P
R
K
P
C
N
Site 64
S591
G
K
G
K
E
G
E
S
D
R
R
H
S
K
G
Site 65
S596
G
E
S
D
R
R
H
S
K
G
C
N
C
K
R
Site 66
Y610
R
S
G
C
L
K
N
Y
C
E
C
Y
E
A
K
Site 67
S635
G
C
K
N
F
E
E
S
P
E
R
K
T
L
M
Site 68
T640
E
E
S
P
E
R
K
T
L
M
H
L
A
D
A
Site 69
T656
E
V
R
V
Q
Q
Q
T
A
A
K
T
K
L
S
Site 70
T660
Q
Q
Q
T
A
A
K
T
K
L
S
S
Q
I
S
Site 71
S663
T
A
A
K
T
K
L
S
S
Q
I
S
D
L
L
Site 72
S664
A
A
K
T
K
L
S
S
Q
I
S
D
L
L
T
Site 73
S667
T
K
L
S
S
Q
I
S
D
L
L
T
R
P
T
Site 74
T671
S
Q
I
S
D
L
L
T
R
P
T
P
A
L
N
Site 75
T674
S
D
L
L
T
R
P
T
P
A
L
N
S
G
G
Site 76
S679
R
P
T
P
A
L
N
S
G
G
G
K
L
P
F
Site 77
S736
C
L
M
S
V
I
N
S
A
G
K
A
K
S
D
Site 78
S742
N
S
A
G
K
A
K
S
D
P
C
A
M
N
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation