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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FSTL4
Full Name:
Follistatin-related protein 4
Alias:
Follistatin-like protein 4
Type:
Mass (Da):
93096
Number AA:
842
UniProt ID:
Q6MZW2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T28
L
G
W
M
D
P
G
T
S
R
G
P
D
V
G
Site 2
S29
G
W
M
D
P
G
T
S
R
G
P
D
V
G
V
Site 3
S39
P
D
V
G
V
G
E
S
Q
A
E
E
P
R
S
Site 4
S46
S
Q
A
E
E
P
R
S
F
E
V
T
R
R
E
Site 5
T50
E
P
R
S
F
E
V
T
R
R
E
G
L
S
S
Site 6
S56
V
T
R
R
E
G
L
S
S
H
N
K
L
L
A
Site 7
S57
T
R
R
E
G
L
S
S
H
N
K
L
L
A
S
Site 8
S64
S
H
N
K
L
L
A
S
C
G
K
K
F
C
S
Site 9
S74
K
K
F
C
S
R
G
S
R
C
V
L
S
R
K
Site 10
S79
R
G
S
R
C
V
L
S
R
K
T
G
E
P
E
Site 11
T82
R
C
V
L
S
R
K
T
G
E
P
E
C
Q
C
Site 12
Y97
L
E
A
C
R
P
S
Y
V
P
V
C
G
S
D
Site 13
S103
S
Y
V
P
V
C
G
S
D
G
R
F
Y
E
N
Site 14
Y108
C
G
S
D
G
R
F
Y
E
N
H
C
K
L
H
Site 15
S130
K
R
I
T
V
I
H
S
K
D
C
F
L
K
G
Site 16
T139
D
C
F
L
K
G
D
T
C
T
M
A
G
Y
A
Site 17
T141
F
L
K
G
D
T
C
T
M
A
G
Y
A
R
L
Site 18
Y145
D
T
C
T
M
A
G
Y
A
R
L
K
N
V
L
Site 19
T157
N
V
L
L
A
L
Q
T
R
L
Q
P
L
Q
E
Site 20
S167
Q
P
L
Q
E
G
D
S
R
Q
D
P
A
S
Q
Site 21
S173
D
S
R
Q
D
P
A
S
Q
K
R
L
L
V
E
Site 22
S181
Q
K
R
L
L
V
E
S
L
F
R
D
L
D
A
Site 23
S195
A
D
G
N
G
H
L
S
S
S
E
L
A
Q
H
Site 24
S196
D
G
N
G
H
L
S
S
S
E
L
A
Q
H
V
Site 25
S197
G
N
G
H
L
S
S
S
E
L
A
Q
H
V
L
Site 26
S217
D
E
D
L
L
G
C
S
P
G
D
L
L
R
F
Site 27
Y227
D
L
L
R
F
D
D
Y
N
S
D
S
S
L
T
Site 28
S229
L
R
F
D
D
Y
N
S
D
S
S
L
T
L
R
Site 29
S231
F
D
D
Y
N
S
D
S
S
L
T
L
R
E
F
Site 30
S232
D
D
Y
N
S
D
S
S
L
T
L
R
E
F
Y
Site 31
S305
N
D
F
G
E
D
D
S
L
Y
I
T
K
V
T
Site 32
Y307
F
G
E
D
D
S
L
Y
I
T
K
V
T
T
I
Site 33
T309
E
D
D
S
L
Y
I
T
K
V
T
T
I
H
M
Site 34
Y346
V
P
P
V
I
R
V
Y
P
E
S
Q
A
Q
E
Site 35
S349
V
I
R
V
Y
P
E
S
Q
A
Q
E
P
G
V
Site 36
S359
Q
E
P
G
V
A
A
S
L
R
C
H
A
E
G
Site 37
T373
G
I
P
M
P
R
I
T
W
L
K
N
G
V
D
Site 38
S382
L
K
N
G
V
D
V
S
T
Q
M
S
K
Q
L
Site 39
T383
K
N
G
V
D
V
S
T
Q
M
S
K
Q
L
S
Site 40
S390
T
Q
M
S
K
Q
L
S
L
L
A
N
G
S
E
Site 41
S401
N
G
S
E
L
H
I
S
S
V
R
Y
E
D
T
Site 42
S402
G
S
E
L
H
I
S
S
V
R
Y
E
D
T
G
Site 43
Y405
L
H
I
S
S
V
R
Y
E
D
T
G
A
Y
T
Site 44
T408
S
S
V
R
Y
E
D
T
G
A
Y
T
C
I
A
Site 45
S427
G
V
D
E
D
I
S
S
L
F
I
E
D
S
A
Site 46
S433
S
S
L
F
I
E
D
S
A
R
K
T
L
A
N
Site 47
T437
I
E
D
S
A
R
K
T
L
A
N
I
L
W
R
Site 48
T479
I
Q
R
H
L
K
P
T
E
K
I
F
M
S
Y
Site 49
S485
P
T
E
K
I
F
M
S
Y
E
E
I
C
P
Q
Site 50
Y486
T
E
K
I
F
M
S
Y
E
E
I
C
P
Q
R
Site 51
T498
P
Q
R
E
K
N
A
T
Q
P
C
Q
W
V
S
Site 52
Y513
A
V
N
V
R
N
R
Y
I
Y
V
A
Q
P
A
Site 53
Y515
N
V
R
N
R
Y
I
Y
V
A
Q
P
A
L
S
Site 54
S548
D
P
L
P
A
K
L
S
Y
D
K
S
H
D
Q
Site 55
S552
A
K
L
S
Y
D
K
S
H
D
Q
V
W
V
L
Site 56
S567
S
W
G
D
V
H
K
S
R
P
S
L
Q
V
I
Site 57
S570
D
V
H
K
S
R
P
S
L
Q
V
I
T
E
A
Site 58
S582
T
E
A
S
T
G
Q
S
Q
H
L
I
R
T
P
Site 59
T588
Q
S
Q
H
L
I
R
T
P
F
A
G
V
D
D
Site 60
Y655
A
H
T
H
L
G
G
Y
F
F
I
Q
C
R
Q
Site 61
S664
F
I
Q
C
R
Q
D
S
P
A
S
A
A
R
Q
Site 62
S667
C
R
Q
D
S
P
A
S
A
A
R
Q
L
L
V
Site 63
S680
L
V
D
S
V
T
D
S
V
L
G
P
N
G
D
Site 64
T689
L
G
P
N
G
D
V
T
G
T
P
H
T
S
P
Site 65
T691
P
N
G
D
V
T
G
T
P
H
T
S
P
D
G
Site 66
S695
V
T
G
T
P
H
T
S
P
D
G
R
F
I
V
Site 67
S703
P
D
G
R
F
I
V
S
A
A
A
D
S
P
W
Site 68
T717
W
L
H
V
Q
E
I
T
V
R
G
E
I
Q
T
Site 69
T724
T
V
R
G
E
I
Q
T
L
Y
D
L
Q
I
N
Site 70
Y726
R
G
E
I
Q
T
L
Y
D
L
Q
I
N
S
G
Site 71
S742
S
D
L
A
F
Q
R
S
F
T
E
S
N
Q
Y
Site 72
T744
L
A
F
Q
R
S
F
T
E
S
N
Q
Y
N
I
Site 73
Y749
S
F
T
E
S
N
Q
Y
N
I
Y
A
A
L
H
Site 74
S798
T
H
R
I
M
R
D
S
G
L
F
G
Q
Y
L
Site 75
T822
L
I
N
G
R
Q
N
T
L
R
C
E
V
S
G
Site 76
S828
N
T
L
R
C
E
V
S
G
I
K
G
G
T
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation