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Updated November 2019
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Protein Info
Short Name:
TET2
Full Name:
Methylcytosine dioxygenase TET2
Alias:
FLJ20032; KIAA1546; LOC54790; Probable methylcytosine dioxygenase TET2: Probable methylcytosine dioxygenase TET2: Probable methylcytosine dioxygenase TET2: TET2 protein; Tet oncogene family member 2
Type:
Mass (Da):
223811
Number AA:
2002
UniProt ID:
Q6N021
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005506
GO:0016706
GO:0016702
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
H
V
E
G
N
R
L
S
P
F
L
I
P
S
P
Site 2
T32
C
Q
T
E
P
L
A
T
K
L
Q
N
G
S
P
Site 3
S38
A
T
K
L
Q
N
G
S
P
L
P
E
R
A
H
Site 4
S69
G
I
P
C
M
K
G
S
Q
N
S
R
V
S
P
Site 5
S75
G
S
Q
N
S
R
V
S
P
D
F
T
Q
E
S
Site 6
T79
S
R
V
S
P
D
F
T
Q
E
S
R
G
Y
S
Site 7
S82
S
P
D
F
T
Q
E
S
R
G
Y
S
K
C
L
Site 8
Y85
F
T
Q
E
S
R
G
Y
S
K
C
L
Q
N
G
Site 9
S86
T
Q
E
S
R
G
Y
S
K
C
L
Q
N
G
G
Site 10
T97
Q
N
G
G
I
K
R
T
V
S
E
P
S
L
S
Site 11
S99
G
G
I
K
R
T
V
S
E
P
S
L
S
G
L
Site 12
S102
K
R
T
V
S
E
P
S
L
S
G
L
L
Q
I
Site 13
S104
T
V
S
E
P
S
L
S
G
L
L
Q
I
K
K
Site 14
S128
E
R
R
N
F
G
V
S
Q
E
R
N
P
G
E
Site 15
S136
Q
E
R
N
P
G
E
S
S
Q
P
N
V
S
D
Site 16
S137
E
R
N
P
G
E
S
S
Q
P
N
V
S
D
L
Site 17
S145
Q
P
N
V
S
D
L
S
D
K
K
E
S
V
S
Site 18
S150
D
L
S
D
K
K
E
S
V
S
S
V
A
Q
E
Site 19
S153
D
K
K
E
S
V
S
S
V
A
Q
E
N
A
V
Site 20
T164
E
N
A
V
K
D
F
T
S
F
S
T
H
N
C
Site 21
S165
N
A
V
K
D
F
T
S
F
S
T
H
N
C
S
Site 22
S167
V
K
D
F
T
S
F
S
T
H
N
C
S
G
P
Site 23
T168
K
D
F
T
S
F
S
T
H
N
C
S
G
P
E
Site 24
S172
S
F
S
T
H
N
C
S
G
P
E
N
P
E
L
Site 25
S214
M
P
N
G
A
T
V
S
A
S
S
V
E
H
T
Site 26
S216
N
G
A
T
V
S
A
S
S
V
E
H
T
H
G
Site 27
T221
S
A
S
S
V
E
H
T
H
G
E
L
L
E
K
Site 28
T229
H
G
E
L
L
E
K
T
L
S
Q
Y
Y
P
D
Site 29
S231
E
L
L
E
K
T
L
S
Q
Y
Y
P
D
C
V
Site 30
Y233
L
E
K
T
L
S
Q
Y
Y
P
D
C
V
S
I
Site 31
Y234
E
K
T
L
S
Q
Y
Y
P
D
C
V
S
I
A
Site 32
S254
S
H
I
N
A
I
N
S
Q
A
T
N
E
L
S
Site 33
S261
S
Q
A
T
N
E
L
S
C
E
I
T
H
P
S
Site 34
T265
N
E
L
S
C
E
I
T
H
P
S
H
T
S
G
Site 35
S268
S
C
E
I
T
H
P
S
H
T
S
G
Q
I
N
Site 36
S276
H
T
S
G
Q
I
N
S
A
Q
T
S
N
S
E
Site 37
S280
Q
I
N
S
A
Q
T
S
N
S
E
L
P
P
K
Site 38
S282
N
S
A
Q
T
S
N
S
E
L
P
P
K
P
A
Site 39
S305
A
D
D
A
D
N
A
S
K
L
A
A
M
L
N
Site 40
S315
A
A
M
L
N
T
C
S
F
Q
K
P
E
Q
L
Site 41
S327
E
Q
L
Q
Q
Q
K
S
V
F
E
I
C
P
S
Site 42
S334
S
V
F
E
I
C
P
S
P
A
E
N
N
I
Q
Site 43
S348
Q
G
T
T
K
L
A
S
G
E
E
F
C
S
G
Site 44
S354
A
S
G
E
E
F
C
S
G
S
S
S
N
L
Q
Site 45
S356
G
E
E
F
C
S
G
S
S
S
N
L
Q
A
P
Site 46
S358
E
F
C
S
G
S
S
S
N
L
Q
A
P
G
G
Site 47
S367
L
Q
A
P
G
G
S
S
E
R
Y
L
K
Q
N
Site 48
Y370
P
G
G
S
S
E
R
Y
L
K
Q
N
E
M
N
Site 49
Y380
Q
N
E
M
N
G
A
Y
F
K
Q
S
S
V
F
Site 50
S385
G
A
Y
F
K
Q
S
S
V
F
T
K
D
S
F
Site 51
T388
F
K
Q
S
S
V
F
T
K
D
S
F
S
A
T
Site 52
S391
S
S
V
F
T
K
D
S
F
S
A
T
T
T
P
Site 53
S393
V
F
T
K
D
S
F
S
A
T
T
T
P
P
P
Site 54
T395
T
K
D
S
F
S
A
T
T
T
P
P
P
P
S
Site 55
T396
K
D
S
F
S
A
T
T
T
P
P
P
P
S
Q
Site 56
T397
D
S
F
S
A
T
T
T
P
P
P
P
S
Q
L
Site 57
S402
T
T
T
P
P
P
P
S
Q
L
L
L
S
P
P
Site 58
S407
P
P
S
Q
L
L
L
S
P
P
P
P
L
P
Q
Site 59
S420
P
Q
V
P
Q
L
P
S
E
G
K
S
T
L
N
Site 60
S424
Q
L
P
S
E
G
K
S
T
L
N
G
G
V
L
Site 61
T425
L
P
S
E
G
K
S
T
L
N
G
G
V
L
E
Site 62
Y437
V
L
E
E
H
H
H
Y
P
N
Q
S
N
T
T
Site 63
S460
G
K
P
E
A
P
P
S
Q
S
P
N
P
S
T
Site 64
S462
P
E
A
P
P
S
Q
S
P
N
P
S
T
H
V
Site 65
S466
P
S
Q
S
P
N
P
S
T
H
V
C
S
P
S
Site 66
T467
S
Q
S
P
N
P
S
T
H
V
C
S
P
S
P
Site 67
S471
N
P
S
T
H
V
C
S
P
S
P
M
L
S
E
Site 68
S473
S
T
H
V
C
S
P
S
P
M
L
S
E
R
P
Site 69
S477
C
S
P
S
P
M
L
S
E
R
P
Q
N
N
C
Site 70
T492
V
N
R
N
D
I
Q
T
A
G
T
M
T
V
P
Site 71
T505
V
P
L
C
S
E
K
T
R
P
M
S
E
H
L
Site 72
S509
S
E
K
T
R
P
M
S
E
H
L
K
H
N
P
Site 73
T549
K
G
R
D
K
E
Q
T
R
D
L
V
P
P
T
Site 74
T556
T
R
D
L
V
P
P
T
Q
H
Y
L
K
P
G
Site 75
Y559
L
V
P
P
T
Q
H
Y
L
K
P
G
W
I
E
Site 76
S585
H
L
K
R
N
E
A
S
L
P
S
I
L
Q
Y
Site 77
Y592
S
L
P
S
I
L
Q
Y
Q
P
N
L
S
N
Q
Site 78
S597
L
Q
Y
Q
P
N
L
S
N
Q
M
T
S
K
Q
Site 79
T601
P
N
L
S
N
Q
M
T
S
K
Q
Y
T
G
N
Site 80
T606
Q
M
T
S
K
Q
Y
T
G
N
S
N
M
P
G
Site 81
S609
S
K
Q
Y
T
G
N
S
N
M
P
G
G
L
P
Site 82
Y620
G
G
L
P
R
Q
A
Y
T
Q
K
T
T
Q
L
Site 83
T646
N
Q
G
Q
S
Q
G
T
V
D
Q
H
L
Q
F
Site 84
S663
P
S
H
Q
V
H
F
S
K
T
D
H
L
P
K
Site 85
S675
L
P
K
A
H
V
Q
S
L
C
G
T
R
F
H
Site 86
S689
H
F
Q
Q
R
A
D
S
Q
T
E
K
L
M
S
Site 87
T691
Q
Q
R
A
D
S
Q
T
E
K
L
M
S
P
V
Site 88
S696
S
Q
T
E
K
L
M
S
P
V
L
K
Q
H
L
Site 89
T710
L
N
Q
Q
A
S
E
T
E
P
F
S
N
S
H
Site 90
S714
A
S
E
T
E
P
F
S
N
S
H
L
L
Q
H
Site 91
T730
P
H
K
Q
A
A
Q
T
Q
P
S
Q
S
S
H
Site 92
S733
Q
A
A
Q
T
Q
P
S
Q
S
S
H
L
P
Q
Site 93
T759
N
K
E
E
I
L
Q
T
F
P
H
P
Q
S
N
Site 94
S765
Q
T
F
P
H
P
Q
S
N
N
D
Q
Q
R
E
Site 95
S774
N
D
Q
Q
R
E
G
S
F
F
G
Q
T
K
V
Site 96
S792
F
H
G
E
N
Q
Y
S
K
S
S
E
F
E
T
Site 97
S794
G
E
N
Q
Y
S
K
S
S
E
F
E
T
H
N
Site 98
T799
S
K
S
S
E
F
E
T
H
N
V
Q
M
G
L
Site 99
S817
Q
N
I
N
R
R
N
S
P
Y
S
Q
T
M
K
Site 100
Y819
I
N
R
R
N
S
P
Y
S
Q
T
M
K
S
S
Site 101
S820
N
R
R
N
S
P
Y
S
Q
T
M
K
S
S
A
Site 102
T822
R
N
S
P
Y
S
Q
T
M
K
S
S
A
C
K
Site 103
S825
P
Y
S
Q
T
M
K
S
S
A
C
K
I
Q
V
Site 104
S826
Y
S
Q
T
M
K
S
S
A
C
K
I
Q
V
S
Site 105
T848
V
S
E
N
K
E
Q
T
T
H
P
E
L
F
A
Site 106
T859
E
L
F
A
G
N
K
T
Q
N
L
H
H
M
Q
Site 107
S890
F
Q
E
Q
E
Q
K
S
Q
Q
A
S
V
L
Q
Site 108
S894
E
Q
K
S
Q
Q
A
S
V
L
Q
G
Y
K
N
Site 109
S907
K
N
R
N
Q
D
M
S
G
Q
Q
A
A
Q
L
Site 110
Y919
A
Q
L
A
Q
Q
R
Y
L
I
H
N
H
A
N
Site 111
S936
P
V
P
D
Q
G
G
S
H
T
Q
T
P
P
Q
Site 112
T938
P
D
Q
G
G
S
H
T
Q
T
P
P
Q
K
D
Site 113
T940
Q
G
G
S
H
T
Q
T
P
P
Q
K
D
T
Q
Site 114
T965
Q
K
Q
E
Q
Q
Q
T
Q
Q
P
Q
T
E
S
Site 115
T970
Q
Q
T
Q
Q
P
Q
T
E
S
C
H
S
Q
M
Site 116
S975
P
Q
T
E
S
C
H
S
Q
M
H
R
P
I
K
Site 117
S1015
K
Q
E
N
P
P
A
S
C
D
N
V
Q
Q
K
Site 118
T1027
Q
Q
K
S
I
I
E
T
M
E
Q
H
L
K
Q
Site 119
S1039
L
K
Q
F
H
A
K
S
L
F
D
H
K
A
L
Site 120
T1047
L
F
D
H
K
A
L
T
L
K
S
Q
K
Q
V
Site 121
S1050
H
K
A
L
T
L
K
S
Q
K
Q
V
K
V
E
Site 122
T1063
V
E
M
S
G
P
V
T
V
L
T
R
Q
T
T
Site 123
T1069
V
T
V
L
T
R
Q
T
T
A
A
E
L
D
S
Site 124
T1070
T
V
L
T
R
Q
T
T
A
A
E
L
D
S
H
Site 125
S1076
T
T
A
A
E
L
D
S
H
T
P
A
L
E
Q
Site 126
T1078
A
A
E
L
D
S
H
T
P
A
L
E
Q
Q
T
Site 127
T1086
P
A
L
E
Q
Q
T
T
S
S
E
K
T
P
T
Site 128
S1087
A
L
E
Q
Q
T
T
S
S
E
K
T
P
T
K
Site 129
T1091
Q
T
T
S
S
E
K
T
P
T
K
R
T
A
A
Site 130
T1093
T
S
S
E
K
T
P
T
K
R
T
A
A
S
V
Site 131
S1107
V
L
N
N
F
I
E
S
P
S
K
L
L
D
T
Site 132
S1109
N
N
F
I
E
S
P
S
K
L
L
D
T
P
I
Site 133
T1114
S
P
S
K
L
L
D
T
P
I
K
N
L
L
D
Site 134
T1122
P
I
K
N
L
L
D
T
P
V
K
T
Q
Y
D
Site 135
T1126
L
L
D
T
P
V
K
T
Q
Y
D
F
P
S
C
Site 136
Y1128
D
T
P
V
K
T
Q
Y
D
F
P
S
C
R
C
Site 137
Y1148
E
K
D
E
G
P
F
Y
T
H
L
G
A
G
P
Site 138
Y1182
I
R
I
E
R
V
I
Y
T
G
K
E
G
K
S
Site 139
S1189
Y
T
G
K
E
G
K
S
S
Q
G
C
P
I
A
Site 140
S1190
T
G
K
E
G
K
S
S
Q
G
C
P
I
A
K
Site 141
S1203
A
K
W
V
V
R
R
S
S
S
E
E
K
L
L
Site 142
S1204
K
W
V
V
R
R
S
S
S
E
E
K
L
L
C
Site 143
S1205
W
V
V
R
R
S
S
S
E
E
K
L
L
C
L
Site 144
Y1245
L
S
L
A
D
K
L
Y
S
E
L
T
E
T
L
Site 145
T1251
L
Y
S
E
L
T
E
T
L
R
K
Y
G
T
L
Site 146
Y1255
L
T
E
T
L
R
K
Y
G
T
L
T
N
R
R
Site 147
T1257
E
T
L
R
K
Y
G
T
L
T
N
R
R
C
A
Site 148
T1259
L
R
K
Y
G
T
L
T
N
R
R
C
A
L
N
Site 149
T1280
C
Q
G
L
D
P
E
T
C
G
A
S
F
S
F
Site 150
S1303
N
G
C
K
F
A
R
S
K
I
P
R
K
F
K
Site 151
S1324
K
E
E
E
K
L
E
S
H
L
Q
N
L
S
T
Site 152
S1330
E
S
H
L
Q
N
L
S
T
L
M
A
P
T
Y
Site 153
T1331
S
H
L
Q
N
L
S
T
L
M
A
P
T
Y
K
Site 154
Y1337
S
T
L
M
A
P
T
Y
K
K
L
A
P
D
A
Site 155
Y1345
K
K
L
A
P
D
A
Y
N
N
Q
I
E
Y
E
Site 156
Y1351
A
Y
N
N
Q
I
E
Y
E
H
R
A
P
E
C
Site 157
S1369
L
K
E
G
R
P
F
S
G
V
T
A
C
L
D
Site 158
T1397
N
G
S
T
L
V
C
T
L
T
R
E
D
N
R
Site 159
T1399
S
T
L
V
C
T
L
T
R
E
D
N
R
E
F
Site 160
Y1421
Q
L
H
V
L
P
L
Y
K
V
S
D
V
D
E
Site 161
S1431
S
D
V
D
E
F
G
S
V
E
A
Q
E
E
K
Site 162
S1448
S
G
A
I
Q
V
L
S
S
F
R
R
K
V
R
Site 163
S1449
G
A
I
Q
V
L
S
S
F
R
R
K
V
R
M
Site 164
T1463
M
L
A
E
P
V
K
T
C
R
Q
R
K
L
E
Site 165
S1481
A
A
A
E
K
L
S
S
L
E
N
S
S
N
K
Site 166
S1485
K
L
S
S
L
E
N
S
S
N
K
N
E
K
E
Site 167
S1494
N
K
N
E
K
E
K
S
A
P
S
R
T
K
Q
Site 168
S1506
T
K
Q
T
E
N
A
S
Q
A
K
Q
L
A
E
Site 169
S1525
S
G
P
V
M
Q
Q
S
Q
Q
P
Q
P
L
Q
Site 170
T1554
Q
Q
P
H
H
P
Q
T
E
S
V
N
S
Y
S
Site 171
S1556
P
H
H
P
Q
T
E
S
V
N
S
Y
S
A
S
Site 172
S1559
P
Q
T
E
S
V
N
S
Y
S
A
S
G
S
T
Site 173
Y1560
Q
T
E
S
V
N
S
Y
S
A
S
G
S
T
N
Site 174
S1561
T
E
S
V
N
S
Y
S
A
S
G
S
T
N
P
Site 175
S1563
S
V
N
S
Y
S
A
S
G
S
T
N
P
Y
M
Site 176
S1565
N
S
Y
S
A
S
G
S
T
N
P
Y
M
R
R
Site 177
Y1569
A
S
G
S
T
N
P
Y
M
R
R
P
N
P
V
Site 178
S1577
M
R
R
P
N
P
V
S
P
Y
P
N
S
S
H
Site 179
Y1579
R
P
N
P
V
S
P
Y
P
N
S
S
H
T
S
Site 180
S1582
P
V
S
P
Y
P
N
S
S
H
T
S
D
I
Y
Site 181
S1583
V
S
P
Y
P
N
S
S
H
T
S
D
I
Y
G
Site 182
S1586
Y
P
N
S
S
H
T
S
D
I
Y
G
S
T
S
Site 183
Y1589
S
S
H
T
S
D
I
Y
G
S
T
S
P
M
N
Site 184
S1593
S
D
I
Y
G
S
T
S
P
M
N
F
Y
S
T
Site 185
Y1598
S
T
S
P
M
N
F
Y
S
T
S
S
Q
A
A
Site 186
S1599
T
S
P
M
N
F
Y
S
T
S
S
Q
A
A
G
Site 187
S1601
P
M
N
F
Y
S
T
S
S
Q
A
A
G
S
Y
Site 188
S1602
M
N
F
Y
S
T
S
S
Q
A
A
G
S
Y
L
Site 189
S1607
T
S
S
Q
A
A
G
S
Y
L
N
S
S
N
P
Site 190
Y1608
S
S
Q
A
A
G
S
Y
L
N
S
S
N
P
M
Site 191
S1611
A
A
G
S
Y
L
N
S
S
N
P
M
N
P
Y
Site 192
S1612
A
G
S
Y
L
N
S
S
N
P
M
N
P
Y
P
Site 193
Y1618
S
S
N
P
M
N
P
Y
P
G
L
L
N
Q
N
Site 194
T1626
P
G
L
L
N
Q
N
T
Q
Y
P
S
Y
Q
C
Site 195
Y1628
L
L
N
Q
N
T
Q
Y
P
S
Y
Q
C
N
G
Site 196
Y1631
Q
N
T
Q
Y
P
S
Y
Q
C
N
G
N
L
S
Site 197
S1643
N
L
S
V
D
N
C
S
P
Y
L
G
S
Y
S
Site 198
Y1645
S
V
D
N
C
S
P
Y
L
G
S
Y
S
P
Q
Site 199
S1648
N
C
S
P
Y
L
G
S
Y
S
P
Q
S
Q
P
Site 200
Y1649
C
S
P
Y
L
G
S
Y
S
P
Q
S
Q
P
M
Site 201
S1650
S
P
Y
L
G
S
Y
S
P
Q
S
Q
P
M
D
Site 202
S1653
L
G
S
Y
S
P
Q
S
Q
P
M
D
L
Y
R
Site 203
Y1659
Q
S
Q
P
M
D
L
Y
R
Y
P
S
Q
D
P
Site 204
Y1661
Q
P
M
D
L
Y
R
Y
P
S
Q
D
P
L
S
Site 205
S1663
M
D
L
Y
R
Y
P
S
Q
D
P
L
S
K
L
Site 206
S1668
Y
P
S
Q
D
P
L
S
K
L
S
L
P
P
I
Site 207
S1671
Q
D
P
L
S
K
L
S
L
P
P
I
H
T
L
Site 208
T1677
L
S
L
P
P
I
H
T
L
Y
Q
P
R
F
G
Site 209
Y1679
L
P
P
I
H
T
L
Y
Q
P
R
F
G
N
S
Site 210
S1686
Y
Q
P
R
F
G
N
S
Q
S
F
T
S
K
Y
Site 211
S1688
P
R
F
G
N
S
Q
S
F
T
S
K
Y
L
G
Site 212
T1690
F
G
N
S
Q
S
F
T
S
K
Y
L
G
Y
G
Site 213
Y1693
S
Q
S
F
T
S
K
Y
L
G
Y
G
N
Q
N
Site 214
S1708
M
Q
G
D
G
F
S
S
C
T
I
R
P
N
V
Site 215
Y1724
H
V
G
K
L
P
P
Y
P
T
H
E
M
D
G
Site 216
T1726
G
K
L
P
P
Y
P
T
H
E
M
D
G
H
F
Site 217
T1737
D
G
H
F
M
G
A
T
S
R
L
P
P
N
L
Site 218
S1738
G
H
F
M
G
A
T
S
R
L
P
P
N
L
S
Site 219
S1745
S
R
L
P
P
N
L
S
N
P
N
M
D
Y
K
Site 220
Y1751
L
S
N
P
N
M
D
Y
K
N
G
E
H
H
S
Site 221
Y1766
P
S
H
I
I
H
N
Y
S
A
A
P
G
M
F
Site 222
S1791
N
K
E
N
D
M
L
S
H
T
A
N
G
L
S
Site 223
S1798
S
H
T
A
N
G
L
S
K
M
L
P
A
L
N
Site 224
T1809
P
A
L
N
H
D
R
T
A
C
V
Q
G
G
L
Site 225
S1820
Q
G
G
L
H
K
L
S
D
A
N
G
Q
E
K
Site 226
S1848
E
D
N
D
E
V
W
S
D
S
E
Q
S
F
L
Site 227
S1850
N
D
E
V
W
S
D
S
E
Q
S
F
L
D
P
Site 228
S1853
V
W
S
D
S
E
Q
S
F
L
D
P
D
I
G
Site 229
T1883
A
K
R
E
L
H
A
T
T
P
L
K
N
P
N
Site 230
T1884
K
R
E
L
H
A
T
T
P
L
K
N
P
N
R
Site 231
S1898
R
N
H
P
T
R
I
S
L
V
F
Y
Q
H
K
Site 232
Y1902
T
R
I
S
L
V
F
Y
Q
H
K
S
M
N
E
Site 233
Y1935
K
E
E
E
C
E
K
Y
G
P
D
Y
V
P
Q
Site 234
Y1939
C
E
K
Y
G
P
D
Y
V
P
Q
K
S
H
G
Site 235
S1944
P
D
Y
V
P
Q
K
S
H
G
K
K
V
K
R
Site 236
T1959
E
P
A
E
P
H
E
T
S
E
P
T
Y
L
R
Site 237
Y1964
H
E
T
S
E
P
T
Y
L
R
F
I
K
S
L
Site 238
S1970
T
Y
L
R
F
I
K
S
L
A
E
R
T
M
S
Site 239
S1977
S
L
A
E
R
T
M
S
V
T
T
D
S
T
V
Site 240
T1979
A
E
R
T
M
S
V
T
T
D
S
T
V
T
T
Site 241
S1982
T
M
S
V
T
T
D
S
T
V
T
T
S
P
Y
Site 242
T1983
M
S
V
T
T
D
S
T
V
T
T
S
P
Y
A
Site 243
T1986
T
T
D
S
T
V
T
T
S
P
Y
A
F
T
R
Site 244
S1987
T
D
S
T
V
T
T
S
P
Y
A
F
T
R
V
Site 245
T1995
P
Y
A
F
T
R
V
T
G
P
Y
N
R
Y
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation