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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM53A
Full Name:
Protein FAM53A
Alias:
DNTNP; Dorsal neural-tube nuclear protein; FA53A
Type:
Nucleus protein
Mass (Da):
42585
Number AA:
398
UniProt ID:
Q6NSI3
International Prot ID:
IPI00095578
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
L
I
T
E
K
L
Q
S
Q
S
L
D
D
L
T
Site 2
S13
T
E
K
L
Q
S
Q
S
L
D
D
L
T
C
K
Site 3
T18
S
Q
S
L
D
D
L
T
C
K
A
E
A
G
P
Site 4
S29
E
A
G
P
L
Q
Y
S
A
E
T
L
N
K
S
Site 5
T32
P
L
Q
Y
S
A
E
T
L
N
K
S
G
R
L
Site 6
S36
S
A
E
T
L
N
K
S
G
R
L
F
P
L
E
Site 7
S48
P
L
E
L
N
D
Q
S
P
W
K
V
F
S
G
Site 8
S54
Q
S
P
W
K
V
F
S
G
G
P
P
V
R
S
Site 9
S61
S
G
G
P
P
V
R
S
Q
A
A
T
G
P
D
Site 10
T65
P
V
R
S
Q
A
A
T
G
P
D
F
S
F
L
Site 11
S90
G
L
Q
W
Q
P
Q
S
P
R
P
G
A
G
L
Site 12
S101
G
A
G
L
G
A
A
S
T
V
D
P
S
E
S
Site 13
T102
A
G
L
G
A
A
S
T
V
D
P
S
E
S
T
Site 14
S106
A
A
S
T
V
D
P
S
E
S
T
G
S
S
T
Site 15
S108
S
T
V
D
P
S
E
S
T
G
S
S
T
A
P
Site 16
S111
D
P
S
E
S
T
G
S
S
T
A
P
P
T
K
Site 17
S112
P
S
E
S
T
G
S
S
T
A
P
P
T
K
R
Site 18
T113
S
E
S
T
G
S
S
T
A
P
P
T
K
R
H
Site 19
T117
G
S
S
T
A
P
P
T
K
R
H
C
R
S
L
Site 20
S123
P
T
K
R
H
C
R
S
L
S
E
P
E
E
L
Site 21
S125
K
R
H
C
R
S
L
S
E
P
E
E
L
V
R
Site 22
S135
E
E
L
V
R
C
R
S
P
W
R
P
G
S
S
Site 23
S141
R
S
P
W
R
P
G
S
S
K
V
W
T
P
V
Site 24
S142
S
P
W
R
P
G
S
S
K
V
W
T
P
V
S
Site 25
T146
P
G
S
S
K
V
W
T
P
V
S
K
R
R
C
Site 26
S149
S
K
V
W
T
P
V
S
K
R
R
C
D
S
G
Site 27
S155
V
S
K
R
R
C
D
S
G
G
S
A
T
R
Q
Site 28
S158
R
R
C
D
S
G
G
S
A
T
R
Q
G
S
P
Site 29
T160
C
D
S
G
G
S
A
T
R
Q
G
S
P
G
A
Site 30
S164
G
S
A
T
R
Q
G
S
P
G
A
V
L
P
R
Site 31
S176
L
P
R
S
A
V
W
S
T
G
P
T
S
P
A
Site 32
T177
P
R
S
A
V
W
S
T
G
P
T
S
P
A
T
Site 33
T180
A
V
W
S
T
G
P
T
S
P
A
T
P
R
P
Site 34
S181
V
W
S
T
G
P
T
S
P
A
T
P
R
P
S
Site 35
T184
T
G
P
T
S
P
A
T
P
R
P
S
S
A
S
Site 36
S188
S
P
A
T
P
R
P
S
S
A
S
G
G
F
V
Site 37
S189
P
A
T
P
R
P
S
S
A
S
G
G
F
V
D
Site 38
S191
T
P
R
P
S
S
A
S
G
G
F
V
D
S
S
Site 39
S197
A
S
G
G
F
V
D
S
S
E
G
S
A
G
S
Site 40
S198
S
G
G
F
V
D
S
S
E
G
S
A
G
S
G
Site 41
S201
F
V
D
S
S
E
G
S
A
G
S
G
P
L
W
Site 42
S204
S
S
E
G
S
A
G
S
G
P
L
W
C
S
A
Site 43
S210
G
S
G
P
L
W
C
S
A
E
S
C
L
P
S
Site 44
S213
P
L
W
C
S
A
E
S
C
L
P
S
T
R
R
Site 45
S217
S
A
E
S
C
L
P
S
T
R
R
R
P
S
L
Site 46
T218
A
E
S
C
L
P
S
T
R
R
R
P
S
L
S
Site 47
S223
P
S
T
R
R
R
P
S
L
S
Q
E
R
L
A
Site 48
S225
T
R
R
R
P
S
L
S
Q
E
R
L
A
G
A
Site 49
T234
E
R
L
A
G
A
G
T
P
L
P
W
A
S
S
Site 50
S240
G
T
P
L
P
W
A
S
S
S
P
T
S
T
P
Site 51
S241
T
P
L
P
W
A
S
S
S
P
T
S
T
P
A
Site 52
S242
P
L
P
W
A
S
S
S
P
T
S
T
P
A
L
Site 53
T244
P
W
A
S
S
S
P
T
S
T
P
A
L
G
G
Site 54
S245
W
A
S
S
S
P
T
S
T
P
A
L
G
G
R
Site 55
T246
A
S
S
S
P
T
S
T
P
A
L
G
G
R
R
Site 56
S260
R
G
L
L
R
C
R
S
Q
P
C
V
L
S
G
Site 57
S266
R
S
Q
P
C
V
L
S
G
K
R
S
R
R
K
Site 58
S270
C
V
L
S
G
K
R
S
R
R
K
R
R
R
E
Site 59
T283
R
E
E
D
A
R
W
T
R
P
S
L
D
F
L
Site 60
S286
D
A
R
W
T
R
P
S
L
D
F
L
K
M
T
Site 61
T293
S
L
D
F
L
K
M
T
Q
T
L
K
N
S
K
Site 62
T295
D
F
L
K
M
T
Q
T
L
K
N
S
K
S
L
Site 63
S301
Q
T
L
K
N
S
K
S
L
C
S
L
N
Y
E
Site 64
S304
K
N
S
K
S
L
C
S
L
N
Y
E
D
D
D
Site 65
Y307
K
S
L
C
S
L
N
Y
E
D
D
D
E
D
D
Site 66
T315
E
D
D
D
E
D
D
T
P
V
K
T
V
L
S
Site 67
T319
E
D
D
T
P
V
K
T
V
L
S
S
P
C
D
Site 68
S322
T
P
V
K
T
V
L
S
S
P
C
D
S
R
G
Site 69
S323
P
V
K
T
V
L
S
S
P
C
D
S
R
G
L
Site 70
T334
S
R
G
L
P
G
I
T
M
P
G
C
S
Q
R
Site 71
S339
G
I
T
M
P
G
C
S
Q
R
G
L
R
T
S
Site 72
S346
S
Q
R
G
L
R
T
S
P
V
H
P
N
L
W
Site 73
S355
V
H
P
N
L
W
A
S
R
E
S
V
T
S
D
Site 74
S358
N
L
W
A
S
R
E
S
V
T
S
D
G
S
R
Site 75
S361
A
S
R
E
S
V
T
S
D
G
S
R
R
S
S
Site 76
S364
E
S
V
T
S
D
G
S
R
R
S
S
G
D
P
Site 77
S367
T
S
D
G
S
R
R
S
S
G
D
P
R
D
G
Site 78
S368
S
D
G
S
R
R
S
S
G
D
P
R
D
G
D
Site 79
S376
G
D
P
R
D
G
D
S
V
G
E
E
G
V
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation