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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
REEP3
Full Name:
Receptor expression-enhancing protein 3
Alias:
C10orf74; Em:AC022387.1; receptor accessory 3; receptor accessory protein 3; receptor expression-enhancing 3
Type:
Membrane protein, integral
Mass (Da):
29264
Number AA:
255
UniProt ID:
Q6NUK4
International Prot ID:
IPI00164434
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y21
F
G
M
L
Y
P
A
Y
Y
S
Y
K
A
V
K
Site 2
T29
Y
S
Y
K
A
V
K
T
K
N
V
K
E
Y
V
Site 3
S97
K
F
L
H
P
L
L
S
S
K
E
R
E
I
D
Site 4
S98
F
L
H
P
L
L
S
S
K
E
R
E
I
D
D
Site 5
Y106
K
E
R
E
I
D
D
Y
I
V
Q
A
K
E
R
Site 6
Y115
V
Q
A
K
E
R
G
Y
E
T
M
V
N
F
G
Site 7
T117
A
K
E
R
G
Y
E
T
M
V
N
F
G
R
Q
Site 8
T135
L
A
A
T
A
A
V
T
A
A
V
K
S
Q
G
Site 9
T145
V
K
S
Q
G
A
I
T
E
R
L
R
S
F
S
Site 10
S150
A
I
T
E
R
L
R
S
F
S
M
H
D
L
T
Site 11
S152
T
E
R
L
R
S
F
S
M
H
D
L
T
T
I
Site 12
T157
S
F
S
M
H
D
L
T
T
I
Q
G
D
E
P
Site 13
T158
F
S
M
H
D
L
T
T
I
Q
G
D
E
P
V
Site 14
Y170
E
P
V
G
Q
R
P
Y
Q
P
L
P
E
A
K
Site 15
S180
L
P
E
A
K
K
K
S
K
P
A
P
S
E
S
Site 16
S185
K
K
S
K
P
A
P
S
E
S
A
G
Y
G
I
Site 17
S187
S
K
P
A
P
S
E
S
A
G
Y
G
I
P
L
Site 18
Y190
A
P
S
E
S
A
G
Y
G
I
P
L
K
D
G
Site 19
T201
L
K
D
G
D
E
K
T
D
E
E
A
E
G
P
Site 20
Y209
D
E
E
A
E
G
P
Y
S
D
N
E
M
L
T
Site 21
S210
E
E
A
E
G
P
Y
S
D
N
E
M
L
T
H
Site 22
T216
Y
S
D
N
E
M
L
T
H
K
G
L
R
R
S
Site 23
S223
T
H
K
G
L
R
R
S
Q
S
M
K
S
V
K
Site 24
S225
K
G
L
R
R
S
Q
S
M
K
S
V
K
T
T
Site 25
S228
R
R
S
Q
S
M
K
S
V
K
T
T
K
G
R
Site 26
T232
S
M
K
S
V
K
T
T
K
G
R
K
E
V
R
Site 27
Y240
K
G
R
K
E
V
R
Y
G
S
L
K
Y
K
V
Site 28
S242
R
K
E
V
R
Y
G
S
L
K
Y
K
V
K
K
Site 29
Y254
V
K
K
R
P
Q
V
Y
F
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation