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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FLJ20581
Full Name:
Acyl-coenzyme A synthetase ACSM5, mitochondrial
Alias:
ACSM5; Acyl-CoA synthetase medium-chain family member 5
Type:
Ligase; Mitochondrial; EC 6.2.1.2; Carbohydrate Metabolism - butanoate
Mass (Da):
64730
Number AA:
UniProt ID:
Q6NUN0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005525
GO:0047760
PhosphoSite+
KinaseNET
Biological Process:
GO:0006631
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
V
L
Q
A
L
R
N
S
R
A
F
C
G
S
H
Site 2
S22
N
S
R
A
F
C
G
S
H
G
K
P
A
P
L
Site 3
Y52
G
R
Q
L
V
P
E
Y
F
N
F
A
H
D
V
Site 4
S91
T
G
A
E
I
K
W
S
F
E
E
L
G
K
Q
Site 5
T138
V
S
V
A
C
M
R
T
G
T
V
M
I
P
G
Site 6
T147
T
V
M
I
P
G
V
T
Q
L
T
E
K
D
L
Site 7
Y156
L
T
E
K
D
L
K
Y
R
L
Q
A
S
R
A
Site 8
S165
L
Q
A
S
R
A
K
S
I
I
T
S
D
S
L
Site 9
S169
R
A
K
S
I
I
T
S
D
S
L
A
P
R
V
Site 10
S171
K
S
I
I
T
S
D
S
L
A
P
R
V
D
A
Site 11
S180
A
P
R
V
D
A
I
S
A
E
C
P
S
L
Q
Site 12
S193
L
Q
T
K
L
L
V
S
D
S
S
R
P
G
W
Site 13
S195
T
K
L
L
V
S
D
S
S
R
P
G
W
L
N
Site 14
S196
K
L
L
V
S
D
S
S
R
P
G
W
L
N
F
Site 15
S211
R
E
L
L
R
E
A
S
T
E
H
N
C
M
R
Site 16
Y228
S
R
D
P
L
A
I
Y
F
T
S
G
T
T
G
Site 17
S243
A
P
K
M
V
E
H
S
Q
S
S
Y
G
L
G
Site 18
S245
K
M
V
E
H
S
Q
S
S
Y
G
L
G
F
V
Site 19
Y247
V
E
H
S
Q
S
S
Y
G
L
G
F
V
A
S
Site 20
T333
L
L
V
Q
E
D
L
T
R
Y
Q
F
Q
S
L
Site 21
Y335
V
Q
E
D
L
T
R
Y
Q
F
Q
S
L
R
H
Site 22
S339
L
T
R
Y
Q
F
Q
S
L
R
H
C
L
T
G
Site 23
T345
Q
S
L
R
H
C
L
T
G
G
E
A
L
N
P
Site 24
Y367
H
Q
T
G
V
E
L
Y
E
G
Y
G
Q
S
E
Site 25
T375
E
G
Y
G
Q
S
E
T
V
V
I
C
A
N
P
Site 26
S389
P
K
G
M
K
I
K
S
G
S
M
G
K
A
S
Site 27
S391
G
M
K
I
K
S
G
S
M
G
K
A
S
P
P
Site 28
S396
S
G
S
M
G
K
A
S
P
P
Y
D
V
Q
I
Site 29
Y399
M
G
K
A
S
P
P
Y
D
V
Q
I
V
D
D
Site 30
Y451
A
S
E
Q
G
D
F
Y
I
T
G
D
R
A
R
Site 31
Y464
A
R
M
D
K
D
G
Y
F
W
F
M
G
R
N
Site 32
S479
D
D
V
I
N
S
S
S
Y
R
I
G
P
V
E
Site 33
S500
E
H
P
A
V
L
E
S
A
A
V
S
S
P
D
Site 34
S504
V
L
E
S
A
A
V
S
S
P
D
P
I
R
G
Site 35
S505
L
E
S
A
A
V
S
S
P
D
P
I
R
G
E
Site 36
Y524
F
I
V
L
T
P
A
Y
S
S
H
D
P
E
A
Site 37
T544
Q
E
H
V
K
R
V
T
A
P
Y
K
Y
P
R
Site 38
Y547
V
K
R
V
T
A
P
Y
K
Y
P
R
K
V
A
Site 39
Y549
R
V
T
A
P
Y
K
Y
P
R
K
V
A
F
V
Site 40
S557
P
R
K
V
A
F
V
S
E
L
P
K
T
V
S
Site 41
T562
F
V
S
E
L
P
K
T
V
S
G
K
I
Q
R
Site 42
S564
S
E
L
P
K
T
V
S
G
K
I
Q
R
S
K
Site 43
S570
V
S
G
K
I
Q
R
S
K
L
R
S
Q
E
W
Site 44
S574
I
Q
R
S
K
L
R
S
Q
E
W
G
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation