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Updated November 2019
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Protein Info
Short Name:
ZNF746
Full Name:
Zinc finger protein 746
Alias:
Type:
Mass (Da):
69136
Number AA:
644
UniProt ID:
Q6NUN9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
A
M
E
R
K
I
E
S
Q
A
A
R
L
L
S
Site 2
S34
S
Q
A
A
R
L
L
S
L
E
G
R
T
G
M
Site 3
T52
K
L
A
D
C
E
K
T
A
V
E
F
G
N
Q
Site 4
T69
G
K
W
A
V
L
G
T
L
L
Q
E
Y
G
L
Site 5
Y74
L
G
T
L
L
Q
E
Y
G
L
L
Q
R
R
L
Site 6
S102
I
L
R
L
P
P
G
S
K
G
E
S
P
K
E
Site 7
S106
P
P
G
S
K
G
E
S
P
K
E
W
G
K
L
Site 8
Y121
E
D
W
Q
K
E
L
Y
K
H
V
M
R
G
N
Site 9
Y129
K
H
V
M
R
G
N
Y
E
T
L
V
S
L
D
Site 10
T131
V
M
R
G
N
Y
E
T
L
V
S
L
D
Y
A
Site 11
S134
G
N
Y
E
T
L
V
S
L
D
Y
A
I
S
K
Site 12
Y137
E
T
L
V
S
L
D
Y
A
I
S
K
P
E
V
Site 13
S140
V
S
L
D
Y
A
I
S
K
P
E
V
L
S
Q
Site 14
S146
I
S
K
P
E
V
L
S
Q
I
E
Q
G
K
E
Site 15
S172
P
D
V
P
V
D
P
S
P
G
S
G
P
P
V
Site 16
S175
P
V
D
P
S
P
G
S
G
P
P
V
P
A
P
Site 17
S222
G
E
E
P
W
G
L
S
Q
L
D
S
G
A
G
Site 18
S226
W
G
L
S
Q
L
D
S
G
A
G
D
I
S
T
Site 19
S232
D
S
G
A
G
D
I
S
T
D
A
T
S
G
V
Site 20
T233
S
G
A
G
D
I
S
T
D
A
T
S
G
V
H
Site 21
T236
G
D
I
S
T
D
A
T
S
G
V
H
S
N
F
Site 22
S237
D
I
S
T
D
A
T
S
G
V
H
S
N
F
S
Site 23
S241
D
A
T
S
G
V
H
S
N
F
S
T
T
I
P
Site 24
S244
S
G
V
H
S
N
F
S
T
T
I
P
P
T
S
Site 25
T245
G
V
H
S
N
F
S
T
T
I
P
P
T
S
W
Site 26
T246
V
H
S
N
F
S
T
T
I
P
P
T
S
W
Q
Site 27
S251
S
T
T
I
P
P
T
S
W
Q
T
D
L
P
P
Site 28
T254
I
P
P
T
S
W
Q
T
D
L
P
P
H
H
P
Site 29
S262
D
L
P
P
H
H
P
S
S
A
C
S
D
G
T
Site 30
S263
L
P
P
H
H
P
S
S
A
C
S
D
G
T
L
Site 31
S266
H
H
P
S
S
A
C
S
D
G
T
L
K
L
N
Site 32
T269
S
S
A
C
S
D
G
T
L
K
L
N
T
A
A
Site 33
T297
Q
E
E
E
V
V
A
T
P
V
H
P
T
D
L
Site 34
T309
T
D
L
E
A
H
G
T
L
F
G
P
G
Q
A
Site 35
S322
Q
A
T
R
F
F
P
S
P
A
Q
E
G
A
W
Site 36
S331
A
Q
E
G
A
W
E
S
Q
G
S
S
F
P
S
Site 37
S334
G
A
W
E
S
Q
G
S
S
F
P
S
Q
D
P
Site 38
S335
A
W
E
S
Q
G
S
S
F
P
S
Q
D
P
V
Site 39
S338
S
Q
G
S
S
F
P
S
Q
D
P
V
L
G
L
Site 40
S359
E
R
D
M
G
E
L
S
P
A
V
A
Q
E
E
Site 41
T367
P
A
V
A
Q
E
E
T
P
P
G
D
W
L
F
Site 42
T395
P
V
G
L
N
P
R
T
G
P
E
G
L
P
Y
Site 43
Y402
T
G
P
E
G
L
P
Y
S
S
P
D
N
G
E
Site 44
S403
G
P
E
G
L
P
Y
S
S
P
D
N
G
E
A
Site 45
S404
P
E
G
L
P
Y
S
S
P
D
N
G
E
A
I
Site 46
S415
G
E
A
I
L
D
P
S
Q
A
P
R
P
F
N
Site 47
Y427
P
F
N
E
P
C
K
Y
P
G
R
T
K
G
F
Site 48
T454
P
P
G
G
R
P
F
T
C
A
T
C
G
K
S
Site 49
S467
K
S
F
Q
L
Q
V
S
L
S
A
H
Q
R
S
Site 50
S469
F
Q
L
Q
V
S
L
S
A
H
Q
R
S
C
G
Site 51
S474
S
L
S
A
H
Q
R
S
C
G
A
P
D
G
S
Site 52
S481
S
C
G
A
P
D
G
S
G
P
G
T
G
G
G
Site 53
T485
P
D
G
S
G
P
G
T
G
G
G
G
S
G
S
Site 54
S490
P
G
T
G
G
G
G
S
G
S
G
G
G
G
G
Site 55
S492
T
G
G
G
G
S
G
S
G
G
G
G
G
G
S
Site 56
S499
S
G
G
G
G
G
G
S
G
G
G
S
A
R
D
Site 57
S503
G
G
G
S
G
G
G
S
A
R
D
G
S
A
L
Site 58
S508
G
G
S
A
R
D
G
S
A
L
R
C
G
E
C
Site 59
T520
G
E
C
G
R
C
F
T
R
P
A
H
L
I
R
Site 60
T541
G
E
R
P
F
P
C
T
E
C
E
K
R
F
T
Site 61
T548
T
E
C
E
K
R
F
T
E
R
S
K
L
I
D
Site 62
S551
E
K
R
F
T
E
R
S
K
L
I
D
H
Y
R
Site 63
Y557
R
S
K
L
I
D
H
Y
R
T
H
T
G
V
R
Site 64
T561
I
D
H
Y
R
T
H
T
G
V
R
P
F
T
C
Site 65
T567
H
T
G
V
R
P
F
T
C
T
V
C
G
K
S
Site 66
T594
N
H
A
A
G
A
K
T
P
A
R
G
Q
P
L
Site 67
T603
A
R
G
Q
P
L
P
T
P
P
A
P
P
D
P
Site 68
S613
A
P
P
D
P
F
K
S
P
A
S
K
G
P
L
Site 69
S616
D
P
F
K
S
P
A
S
K
G
P
L
A
S
T
Site 70
S634
T
D
W
T
C
G
L
S
V
L
G
P
T
D
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation