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Updated November 2019
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Protein Info
Short Name:
DPY19L2
Full Name:
Protein dpy-19 homolog 2
Alias:
Dpy-19-like protein 2
Type:
Mass (Da):
87374
Number AA:
758
UniProt ID:
Q6NUT2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
R
K
Q
G
V
S
S
K
R
L
Q
S
S
Site 2
S8
M
R
K
Q
G
V
S
S
K
R
L
Q
S
S
G
Site 3
S13
V
S
S
K
R
L
Q
S
S
G
R
S
Q
S
K
Site 4
S14
S
S
K
R
L
Q
S
S
G
R
S
Q
S
K
G
Site 5
S17
R
L
Q
S
S
G
R
S
Q
S
K
G
R
R
G
Site 6
S19
Q
S
S
G
R
S
Q
S
K
G
R
R
G
A
S
Site 7
S26
S
K
G
R
R
G
A
S
L
A
R
E
P
E
V
Site 8
S40
V
E
E
E
M
E
K
S
A
L
G
G
G
K
L
Site 9
S51
G
G
K
L
P
R
G
S
W
R
S
S
P
G
R
Site 10
S54
L
P
R
G
S
W
R
S
S
P
G
R
I
Q
S
Site 11
S55
P
R
G
S
W
R
S
S
P
G
R
I
Q
S
L
Site 12
S61
S
S
P
G
R
I
Q
S
L
K
E
R
K
G
L
Site 13
S88
P
F
Q
F
V
R
N
S
L
A
Q
L
R
E
K
Site 14
S105
E
L
Q
A
R
R
F
S
S
R
T
T
L
G
I
Site 15
S106
L
Q
A
R
R
F
S
S
R
T
T
L
G
I
A
Site 16
S135
F
E
N
D
R
H
F
S
H
L
S
S
L
E
R
Site 17
S138
D
R
H
F
S
H
L
S
S
L
E
R
E
M
T
Site 18
S139
R
H
F
S
H
L
S
S
L
E
R
E
M
T
F
Site 19
T145
S
S
L
E
R
E
M
T
F
R
T
E
M
G
L
Site 20
Y153
F
R
T
E
M
G
L
Y
Y
S
Y
F
K
T
I
Site 21
Y154
R
T
E
M
G
L
Y
Y
S
Y
F
K
T
I
I
Site 22
S234
E
P
L
N
E
V
Q
S
C
E
G
L
G
D
P
Site 23
T294
E
A
T
R
V
M
W
T
P
P
L
R
E
S
F
Site 24
S300
W
T
P
P
L
R
E
S
F
S
Y
P
F
L
V
Site 25
S302
P
P
L
R
E
S
F
S
Y
P
F
L
V
L
Q
Site 26
S320
L
T
L
I
L
R
T
S
S
N
D
R
R
P
F
Site 27
S321
T
L
I
L
R
T
S
S
N
D
R
R
P
F
I
Site 28
Y393
L
M
F
G
N
S
M
Y
L
S
S
Y
Y
S
S
Site 29
S395
F
G
N
S
M
Y
L
S
S
Y
Y
S
S
S
L
Site 30
S396
G
N
S
M
Y
L
S
S
Y
Y
S
S
S
L
L
Site 31
Y397
N
S
M
Y
L
S
S
Y
Y
S
S
S
L
L
M
Site 32
S451
T
S
K
I
L
G
V
S
D
H
I
R
L
S
D
Site 33
Y475
T
D
F
D
T
L
I
Y
T
C
A
P
E
F
D
Site 34
T488
F
D
F
M
E
K
A
T
P
L
R
Y
T
K
T
Site 35
S517
K
K
T
V
R
D
I
S
Y
V
L
A
T
N
I
Site 36
Y525
Y
V
L
A
T
N
I
Y
L
R
K
Q
L
L
E
Site 37
Y602
T
V
M
S
I
Q
G
Y
A
N
L
R
N
Q
W
Site 38
Y629
E
L
L
Q
W
I
K
Y
S
T
T
S
D
A
V
Site 39
T643
V
F
A
G
A
M
P
T
M
A
S
I
K
L
S
Site 40
S646
G
A
M
P
T
M
A
S
I
K
L
S
T
L
H
Site 41
Y661
P
I
V
N
H
P
H
Y
E
D
A
D
L
R
A
Site 42
T670
D
A
D
L
R
A
R
T
K
I
V
Y
S
T
Y
Site 43
Y674
R
A
R
T
K
I
V
Y
S
T
Y
S
R
K
S
Site 44
T676
R
T
K
I
V
Y
S
T
Y
S
R
K
S
A
K
Site 45
Y677
T
K
I
V
Y
S
T
Y
S
R
K
S
A
K
E
Site 46
S681
Y
S
T
Y
S
R
K
S
A
K
E
V
R
D
K
Site 47
S724
I
W
D
V
E
D
P
S
N
A
A
N
P
P
L
Site 48
Y742
L
L
E
D
A
R
P
Y
F
T
T
V
F
Q
N
Site 49
T745
D
A
R
P
Y
F
T
T
V
F
Q
N
S
V
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation