KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF774
Full Name:
Zinc finger protein 774
Alias:
Type:
Mass (Da):
55040
Number AA:
483
UniProt ID:
Q6NX45
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
W
L
G
T
S
G
K
S
G
L
P
G
H
C
L
Site 2
S37
E
W
A
L
K
G
I
S
R
P
S
V
I
S
Q
Site 3
S40
L
K
G
I
S
R
P
S
V
I
S
Q
P
E
Q
Site 4
S43
I
S
R
P
S
V
I
S
Q
P
E
Q
K
E
E
Site 5
S68
A
R
K
I
P
R
E
S
H
T
D
C
E
H
Q
Site 6
S83
V
A
K
L
N
Q
D
S
S
E
T
A
E
Q
C
Site 7
S84
A
K
L
N
Q
D
S
S
E
T
A
E
Q
C
G
Site 8
T92
E
T
A
E
Q
C
G
T
S
S
E
R
T
N
K
Site 9
S94
A
E
Q
C
G
T
S
S
E
R
T
N
K
D
L
Site 10
T97
C
G
T
S
S
E
R
T
N
K
D
L
S
H
T
Site 11
S102
E
R
T
N
K
D
L
S
H
T
L
S
W
G
G
Site 12
T104
T
N
K
D
L
S
H
T
L
S
W
G
G
N
W
Site 13
S106
K
D
L
S
H
T
L
S
W
G
G
N
W
E
Q
Site 14
S132
P
G
E
G
Q
L
E
S
F
S
Q
E
R
D
L
Site 15
S134
E
G
Q
L
E
S
F
S
Q
E
R
D
L
N
K
Site 16
Y146
L
N
K
L
L
D
G
Y
V
G
E
K
P
M
C
Site 17
S163
C
G
K
S
F
N
Q
S
S
Y
L
I
R
H
L
Site 18
S164
G
K
S
F
N
Q
S
S
Y
L
I
R
H
L
R
Site 19
T174
I
R
H
L
R
T
H
T
G
E
R
P
Y
T
C
Site 20
Y179
T
H
T
G
E
R
P
Y
T
C
I
E
C
G
K
Site 21
T180
H
T
G
E
R
P
Y
T
C
I
E
C
G
K
G
Site 22
S191
C
G
K
G
F
K
Q
S
S
D
L
V
T
H
R
Site 23
S192
G
K
G
F
K
Q
S
S
D
L
V
T
H
R
R
Site 24
T196
K
Q
S
S
D
L
V
T
H
R
R
T
H
T
G
Site 25
T200
D
L
V
T
H
R
R
T
H
T
G
E
K
P
Y
Site 26
T202
V
T
H
R
R
T
H
T
G
E
K
P
Y
Q
C
Site 27
Y207
T
H
T
G
E
K
P
Y
Q
C
K
G
C
E
K
Site 28
S217
K
G
C
E
K
K
F
S
D
S
S
T
L
I
K
Site 29
S219
C
E
K
K
F
S
D
S
S
T
L
I
K
H
Q
Site 30
T221
K
K
F
S
D
S
S
T
L
I
K
H
Q
R
T
Site 31
T230
I
K
H
Q
R
T
H
T
G
E
R
P
Y
E
C
Site 32
Y235
T
H
T
G
E
R
P
Y
E
C
P
E
C
G
K
Site 33
T243
E
C
P
E
C
G
K
T
F
G
R
K
P
H
L
Site 34
T256
H
L
I
M
H
Q
R
T
H
T
G
E
K
P
Y
Site 35
T258
I
M
H
Q
R
T
H
T
G
E
K
P
Y
A
C
Site 36
Y263
T
H
T
G
E
K
P
Y
A
C
L
E
C
H
K
Site 37
S271
A
C
L
E
C
H
K
S
F
S
R
S
S
N
F
Site 38
S273
L
E
C
H
K
S
F
S
R
S
S
N
F
I
T
Site 39
S275
C
H
K
S
F
S
R
S
S
N
F
I
T
H
Q
Site 40
S276
H
K
S
F
S
R
S
S
N
F
I
T
H
Q
R
Site 41
T280
S
R
S
S
N
F
I
T
H
Q
R
T
H
T
G
Site 42
T286
I
T
H
Q
R
T
H
T
G
V
K
P
Y
R
C
Site 43
S299
R
C
N
D
C
G
E
S
F
S
Q
S
S
D
L
Site 44
S301
N
D
C
G
E
S
F
S
Q
S
S
D
L
I
K
Site 45
S303
C
G
E
S
F
S
Q
S
S
D
L
I
K
H
Q
Site 46
T314
I
K
H
Q
R
T
H
T
G
E
R
P
F
K
C
Site 47
S332
G
K
G
F
R
D
S
S
H
F
V
A
H
M
S
Site 48
S348
H
S
G
E
R
P
F
S
C
P
D
C
H
K
S
Site 49
S355
S
C
P
D
C
H
K
S
F
S
Q
S
S
H
L
Site 50
S357
P
D
C
H
K
S
F
S
Q
S
S
H
L
V
T
Site 51
S359
C
H
K
S
F
S
Q
S
S
H
L
V
T
H
Q
Site 52
T364
S
Q
S
S
H
L
V
T
H
Q
R
T
H
T
G
Site 53
T370
V
T
H
Q
R
T
H
T
G
E
R
P
F
K
C
Site 54
S387
C
G
K
G
F
A
D
S
S
A
L
I
K
H
Q
Site 55
S388
G
K
G
F
A
D
S
S
A
L
I
K
H
Q
R
Site 56
T398
I
K
H
Q
R
I
H
T
G
E
R
P
Y
K
C
Site 57
Y403
I
H
T
G
E
R
P
Y
K
C
G
E
C
G
K
Site 58
S416
G
K
S
F
N
Q
S
S
H
F
I
T
H
Q
R
Site 59
T420
N
Q
S
S
H
F
I
T
H
Q
R
I
H
L
G
Site 60
Y431
I
H
L
G
D
R
P
Y
R
C
P
E
C
G
K
Site 61
T448
N
Q
R
S
H
F
L
T
H
Q
R
T
H
T
G
Site 62
T452
H
F
L
T
H
Q
R
T
H
T
G
E
K
P
F
Site 63
T454
L
T
H
Q
R
T
H
T
G
E
K
P
F
H
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation